Patents by Inventor MARTIN SILL

MARTIN SILL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240331864
    Abstract: The present disclosure relates to a computer-implemented method for cancer diagnosis, comprising: a) selectively sequencing polymers of a biological sample according to at least one target gene site by translocating the polymers through nanopores of a nanopore sequencing system, including: (i) analyzing an initial nucleotide sequence of a first polymer of the biological sample while the first polymer is translocating through a nanopore of the nanopore sequencing system to determine whether the initial nucleotide sequence corresponds to the at least one target gene site; and (ii) continuing the sequencing of the first polymer to obtain measurement data of the first polymer only if the initial nucleotide sequence of the first polymer corresponds to the at least one target gene site: b) determining, based on the measurement data, a biological state of a nucleotide sequence of the first polymer corresponding to the at least one target gene site; and c) classifying a cancer using a classification algorithm based o
    Type: Application
    Filed: August 4, 2022
    Publication date: October 3, 2024
    Applicants: DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OEFFENTLICHEN RECHTS, UNIVERSITAET HEIDELBERG, OXFORD NANOPORE TECHNOLOGIES PLC
    Inventors: Felix SAHM, Martin SILL, Andreas VON DEIMLING, Stefan PFISTER, David JONES, Areeba PATEL, Helin DOGAN, Matt LOOSE, Alexander PAYNE
  • Publication number: 20180066317
    Abstract: The present invention pertains to methods for classifying tumorous diseases based on their specific genomic DNA methylation profile. The invention provides a method that allows for a classification of a tumor sample obtained from a patient by analysing a multitude, preferably genome wide, collection of CpG positions by comparison to a classification rule derived from a set of methylation data acquired from pre-classified tumor species. The invention is in particular useful for classifying brain tumor samples since brain tumors are characterized by a large variety of distinct tumor species which have different prognostic values and require in the clinic a for each species developed treatment regime.
    Type: Application
    Filed: September 15, 2016
    Publication date: March 8, 2018
    Applicants: Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts, Ruprecht-Karls-Universität Heidelberg
    Inventors: STEFAN PFISTER, ANDREAS VON DEIMLING, DAVID JONES, DAVID CAPPER, VOLKER HOVESTADT, MARTIN SILL, MELANIE BEWERUNGE-HUDLER, MATTHIAS SCHICK
  • Patent number: 8030629
    Abstract: The invention relates to an adaptive optical device for the reflection of impinging radiation, the adaptive optical device comprising at least one actuator and at least one partially reflective volume. The at least one partially reflective volume has a first surface that is oriented to the impinging radiation. The at least one partially reflective volume is at least partially deformable by said at least one actuator such that the impinging radiation is reflected at the at least one partially reflective volume substantially in accordance with Bragg's law. Further, the invention relates to a method and apparatus for controlling the shape of an adaptive optical device.
    Type: Grant
    Filed: December 6, 2007
    Date of Patent: October 4, 2011
    Assignee: Westfälische Wilhelms-Universität Münster
    Inventors: Zacharias Helmut, Martin Silles