Patents by Inventor Martin SMIESKO

Martin SMIESKO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HALOALKYL FUCOSE-CONTAINING SELECTIN ANTAGONISTS
    Publication number: 20200316100
    Abstract: Compounds, compositions, and methods for treatment and/or prevention of at least one disease, disorder, and/or condition by inhibiting binding of an E-selectin to an E-selectin ligand are disclosed. For example, haloalkyl fucose-containing E-selectin antagonists and compositions comprising at least one such agent are described.
    Type: Application
    Filed: May 22, 2017
    Publication date: October 8, 2020
    Applicant: GycoMimetics, Inc.
    Inventors: Beat ERNST, Norbert VARGA, Martin SMIESKO, Beatrice WAGNER, John M. PETERSON, John L. MAGNANI
  • E-Selectin Antagonists Modified By Macrocycle Formation to the Galactose
    Publication number: 20160333043
    Abstract: Provided herein are glycomimetic E-selectin antagonist compounds of formula (I)) and pharmaceutical compositions comprising at least one of the same. The compounds of the present disclosure include trisaccharide domain mimics comprising at least one macrocycle created through the 2nd and 3rd positions on a galactose within the mimic. Methods are also provided comprising using at least one of such compounds and compositions comprising at least one of the same to treat and/or prevent diseases and disorders treatable by inhibiting binding of an E-selectin to an E-selectin ligand.
    Type: Application
    Filed: January 15, 2015
    Publication date: November 17, 2016
    Applicant: GLYCOMIMETICS, INC.
    Inventors: John L. MAGNANI, John M. PETERSON, Mirko ZIERKE, Martin SMIESKO, Beat ERNST