Abstract: Novel dry powder compositions comprising and methods relating thereto are provided. The dry powder compositions comprise PDE5 inhibitors, such as vardenafil, or pharmaceutically acceptable salts or esters thereof. The dry powder compositions may optionally include an carrier/excipient. The concentration of active agent may be at least about 2% by weight. Methods of aerosolizing the dry powder compositions and using them to treat various diseases are also disclosed.

Abstract: Novel dry powder compositions comprising and methods relating thereto are provided. The dry powder compositions comprise PDE5 inhibitors, such as vardenafil, or pharmaceutically acceptable salts or esters thereof. The dry powder compositions may optionally include an carrier/excipient. The concentration of active agent may be at least about 2% by weight. Methods of aerosolizing the dry powder compositions and using them to treat various diseases are also disclosed.

Abstract: Cyanoacrylate compositions are provided, which when cured provide improved hot strength performance without compromising thermal resistance performance.

Abstract: A container for curable cyanoacrylate composition comprising: a reservoir for holding curable cyanoacrylate composition, the reservoir having an outlet through which the curable cyanoacrylate composition can be dispensed; the reservoir being defined by walls of plastics material, the plastics material being formed by a polymer material that is transmissive to both visible light and UV light; and a UV blocking agent dispersed in the plastics material the UV blocking agent comprising at least one benzotriazole; the walls of the container being transmissive to visible light and non-transmissive to UV light. Curable cyanoacrylate compositions held within such a container are thus storage stable in ambient conditions and yet the curable cyanoacrylate compositions can be seen through the walls of the container. A pack comprising the container and a curable cyanoacrylate composition is also described.

Abstract: Photocurable (meth)acrylate compositions with low viscosity when uncured, and high flexibility and shear/tensile strength when cured, further possessing rapid tack-free fixture times, comprising mixtures of urethane acrylate resin, isobornyl acrylate, N,N-dimethylacrylamide, a photoinitiator component, and a low percentage of tetrahydrofurfuryl acrylate, for example from about 9% to about 15% by weight based on the weight of the composition. Applications can include adhesive bonding of medical tubing, UV/Visible transparent plastics material medical devices or equipment, or other flexible UV/Visible transparent material substrates.

Abstract: Methods for manufacturing three-dimensional articles having reduced surface haze, by applying a coating to the surface of a three-dimensional article made by additive manufacturing are described.

Abstract: Photocurable (meth)acrylate compositions with low viscosity when uncured, and high flexibility and shear/tensile strength when cured, further possessing rapid tack-free fixture times, comprising mixtures of urethane acrylate resin, isobornyl acrylate, N,N-dimethylacrylamide, a photoinitiator component, and a low percentage of tetrahydrofurfuryl acrylate, for example from about 9% to about 15% by weight based on the weight of the composition. Applications can include adhesive bonding of medical tubing, UV/Visible transparent plastics material medical devices or equipment, or other flexible UV/Visible transparent material substrates.