Abstract: A combinatorial drug delivery device is provided for delivering a predetermined selection of drug components, each of the drug components being contained in a drug vial. The device includes a plurality of modules, wherein each of the modules includes: a body having an interior volume formed to accommodate a drug vial; a cannula protruding into the interior volume, the cannula terminating at a free end, first and second openings being formed in the free end with first and second lumens extending therefrom and through the cannula; a socket located on an exterior portion of the body; a first passageway extending between, and in communication with, the socket and the first lumen; a boss protruding from an exterior portion of the body; and, a second passageway extending from, and in communication with the second lumen, the second passageway extending through the boss to terminate at an exit opening formed therein.

Abstract: In one aspect, a drug delivery device is provided herein including: a monolithic body having a plurality of fluid ducts and at least one outlet duct formed therein; a plurality of drug cartridges attached to the body, the drug cartridges each including a reservoir for accommodating at least one drug wherein, the plurality of fluid ducts is arranged to convey the drugs from the drug cartridges to the at least one outlet duct; and, a needle support spaced from the body, the needle support including a needle configured for insertion into a patient for drug delivery, the needle support including adhesive for releasable securement to a patient, wherein, the needle support is connected to the body by a flexible tether through which passes at least one fluid passageway formed to convey drug from the at least one outlet duct to the needle.

Abstract: A computer implemented system and a method for providing user related data, such as reputational information, on users of a blockchain involved in transactions is detailed. The method includes an approach for evaluating fulfilment of transactions, particularly in the context of contracts, and then providing a record of that on the blockchain through reputational information. As a result, at a late time, this reputational information can be retrieved. Similar reputational information for other transactions can be retrieved and linked to the same user, for instance based on the use of a hash of the master public key for a user. Aggregate reputational information can be computed from the pieces of reputational information retrieved.

Abstract: A combinatorial drug delivery device is provided for delivering a predetermined selection of drug components, each of the drug components being contained in a drug vial. The device includes a plurality of modules, wherein each of the modules includes: a body having an interior volume formed to accommodate a drug vial; a cannula protruding into the interior volume, the cannula terminating at a free end, first and second openings being formed in the free end with first and second lumens extending therefrom and through the cannula; a socket located on an exterior portion of the body; a first passageway extending between, and in communication with, the socket and the first lumen; a boss protruding from an exterior portion of the body; and, a second passageway extending from, and in communication with the second lumen, the second passageway extending through the boss to terminate at an exit opening formed therein.

Abstract: In one aspect, a method is provided herein of preparing a drug delivery device, the drug delivery device having a body with at least one fluid duct being open along a first face of the body, the at least one fluid duct for conveying drug from at least one reservoir to a needle configured for injection into a patient, the method including: providing a barrier across the first face of the body to at least cover the at least one fluid duct, wherein the barrier is ultraviolet transmissive; and, exposing the first face of the body to ultraviolet radiation so as to allow the ultraviolet radiation to pass through the barrier and decontaminate the at least one fluid duct.

Abstract: From an unstructured content using an ontology, a forward materialization graph is generated. The forward materialization graph is converted to a set of vector representations comprising multidimensional numbers representing elements of the forward materialization graph. A set of inference paths is computed for the set of vector representations. An inference path in the set of inference paths connecting a first vector representation with a second vector representation. Based on a set of features, the set of vector representations is formed into clusters, a feature in the set of features comprising a relevance probability, the relevance probability corresponding to a relevance of a portion of the unstructured content according to a relevance metric. A structured representation of the unstructured content is placed at an edge location of a content delivery network determined using the set of clusters.

Abstract: The disclosure is directed at a method and system for synchronizing inputs transmitted over the Internet from a set of devices. The disclosure transmits a set of individual timing packets to each of the set of devices and, after receiving a set of return individual timing packets, determines a round trip time for each of the set of return individual timing packets. The round trip time is then used to calculate a timeslot offset for each of the devices which is then used to synchronize the transmission of data between the disclosure and the set of devices.

Abstract: A method is proposed of encoding a change time The change time indicates a change in time of a characteristic luminance of the video data. The characteristic luminance summarizes the set of luminances of pixels the video data. The encoding of the time variation of the characteristic luminance provides a more compact and accurate storage and transmission of content.

Abstract: Protection apparatus for a flexible elongate member. The apparatus comprises a plurality of protection members 10. Each protection member 10 defines an opening 22 through which a flexible elongate member can extend. Each protection member 10 is interconnectable end to end with other such protection members 10 to provide protection along the length of an elongate member. Each protection member 10 comprises two parts 12 which are mountable together to define the opening 22 through which an elongate member can extend. The two parts 12 together form a female formation 18 at one end, and a male formation 20 at the other end, such that the female formation 18 can receive a male formation 20 on an adjacent protection member 10 to interconnect the adjacent projection members 10. The female and male formations 18, 20 are configured to permit a predetermined amount of relative pivotal movement between adjacent protection members 10.

Abstract: A bicycle has a front fork, within which the front wheel is mounted, attached to the head tube. Extending downwardly from each end of a lateral member are downwardly projecting forks, each comprising a primary portion, the respective primary portions extending downwardly and substantially parallel to each other. The longitudinal axes of both the main portion and a rider's lower leg are aligned. By aligning the wakes created by the forks and the lower leg a reduction in overall system drag is provided. Additionally or alternatively, the rear wheel may be provided between downwardly projecting stays, each comprising a primary portion, the respective primary portions extending downwardly and substantially parallel to each other. By aligning the downwardly projecting stays with the lower leg beneficial drag reduction is achieved.

Abstract: Protection apparatus for a flexible elongate member. The apparatus comprises a plurality of protection members 10. Each protection member 10 defines an opening 22 through which a flexible elongate member can extend. Each protection member 10 is interconnectable end to end with other such protection members 10 to provide protection along the length of an elongate member. Each protection member 10 comprises two parts 12 which are mountable together to define the opening 22 through which an elongate member can extend. The two parts 12 together form a female formation 18 at one end, and a male formation 20 at the other end, such that the female formation 18 can receive a male formation 20 on an adjacent protection member 10 to interconnect the adjacent projection members 10. The female and male formations 18, 20 are configured to permit a predetermined amount of relative pivotal movement between adjacent protection members 10.

Abstract: Guide apparatus for an elongate member such as a pipeline or pipe. The apparatus comprising a plurality of first elements in the form of rings with central openings through which the elongate member extends. The first elements are interconnected by link members spaced around the outside of the first elements and locating in T-shaped cross section guide formations. The link members restrict the amount of pivotal movement between the first elements, and hence bending of the elongate member.

Abstract: A mounting arrangement for mounting one or more additional elongate members on a larger existing elongate member. The arrangement includes a base member mountable on the outside of the larger pipe and can be held thereon by a strap engaging with ratchet arrangements on the arrangement. A guide member with a generally n shaped configuration which may include an insert member, guides the smaller pipe or pipes.

Abstract: A clamping arrangement 10 of a buoyancy clamp assembly. The arrangement 10 includes three identical arcuate members 12 engageable together to define a ring. Each of the arcuate members 12 has three discrete resilient members 14 engageable on for instance a pipe 68. Engagement members 42 are provided extendable between adjacent pair of arcuate members 12 to prevent relative twisting of adjacent arcuate members 12.

Abstract: A mounting arrangement 10 for mounting one or more additional elongate members such as pipes 12 on a larger existing elongate member such as a larger pipe 14. The arrangement 10 includes a base member 16 mountable on the outside of the larger pipe 14, and can be held thereon by a strap 96 engaging with ratchet arrangements on the arrangement 10. A guide member 82 with a generally n shaped configuration which may include an insert member 88, guides the smaller pipe or pipes 12.

Abstract: A computing device executes a “night mode” for optimizing the device display's light emission for night-time use. The device stores a dimming filter and/or a color filter to achieve a desired brightness and color temperature of the display. The dimming filter is used to set a display backlight level and to “dim” the display data itself via alpha blending of the screen image with a grey mask. The computing device can blend the image with the grey mask in order to dim the display below system minimums. The color filter is alpha blended with each pixel in the image to reduce the luminance of blue light until the luminance is lower than that of another color of the emitted light. The proper dimming and color filters may be selected according to a desired screen brightness obtained from user input and/or from ambient light sensor data.

Abstract: A clamping arrangement 10 of a buoyancy clamp assembly. The arrangement 10 includes three identical arcuate members 12 engageable together to define a ring. Each of the arcuate members 12 has three discrete resilient members 14 engageable on for instance a pipe 68. Engagement members 42 are provided extendable between adjacent pair of arcuate members 12 to prevent relative twisting of adjacent arcuate members 12.

Abstract: For continuous-time multi-stage noise shaping analog-to-digital converters (CT MASH ADCs), quantization noise cancellation often requires accurate estimation of transfer functions, e.g., a noise transfer function of the front end modulator and a signal transfer function of the back end modulator. To provide quantization noise cancellation, digital quantization noise cancellation filters adaptively tracks transfer function variations due to integrator gain errors, flash-to-DAC timing errors, as well as the inter-stage gain and timing errors. Tracking the transfer functions is performed through the direct cross-correlation between the injected maximum length linear feedback shift registers (LFSR) sequence and modulator outputs and then corrects these non-ideal effects by accurately modeling the transfer functions with programmable finite impulse response (PFIR) filters.

Abstract: For small cells, transceivers demand high performance while maintaining system efficiency. The present disclosure describes a highly integrated cellular transceiver that offers such features by providing one or more digital functions on-chip, onto the same die in the cellular transceiver. Effectively, the scope and boundary of the cellular transceiver is expanded to move beyond the data converters of the transceiver to include a variety of digital functions, thus integrating more of the signal chain in the cellular transceiver. Integration can greatly reduce complexity for the baseband processing, lower the cost of the overall transceiver system, reduce power consumption, and at the same time, benefit from improvements on the digital functions through integration.

Abstract: For continuous-time multi-stage noise shaping analog-to-digital converters (CT MASH ADCs), quantization noise cancellation often requires accurate estimation of transfer functions, e.g., a noise transfer function of the front end modulator and a signal transfer function of the back end modulator. To provide quantization noise cancellation, digital quantization noise cancellation filters adaptively tracks transfer function variations due to integrator gain errors, flash-to-DAC timing errors, as well as the inter-stage gain and timing errors. Tracking the transfer functions is performed through the direct cross-correlation between the injected maximum length linear feedback shift registers (LFSR) sequence and modulator outputs and then corrects these non-ideal effects by accurately modeling the transfer functions with programmable finite impulse response (PFIR) filters.