Patents by Inventor Martin Szelagiewicz

Martin Szelagiewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6939992
    Abstract: A crystalline form of sertraline hydrochloride was found, referred to hereinafter as polymorphic form CSC2 having a dissolution rate which surprisingly will increase rate of absorption of a drug. Furthermore, different crystalline forms of sertraline hydrochloride alcohol solvates, crystalline forms of sertraline hydrochloride hydrates, referred to hereinafter as polymorphic form CSC1, a process for the preparation of the amorphous form of sertraline hydrochloride, and different processes for the preparation of polymorphic forms I, II, V, and T1 are disclosed.
    Type: Grant
    Filed: December 15, 2003
    Date of Patent: September 6, 2005
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Paul Adriaan Van Der Schaaf, Franz Schwarzenbach, Hans-Jörg Kirner, Martin Szelagiewicz, Claudia Marcolli, Andreas Burkhard
  • Patent number: 6906087
    Abstract: Crystalline forms of Venlafaxine hydrochloride were found, referred to hereinafter as polymorphic Forms A, B and D. Furthermore, the present invention is directed to processes for the preparation of these crystalline forms and pharmaceutical compositions comprising the crystalline forms.
    Type: Grant
    Filed: October 23, 2001
    Date of Patent: June 14, 2005
    Assignee: Ciba Specialty Chemicals Corpation
    Inventors: Paul Adriaan Van Der Schaaf, Claudia Marcolli, Martin Szelagiewicz, Beat Freiermuth
  • Publication number: 20050119351
    Abstract: An improved process for the preparation of sertraline hydrochloride polymorphic form II is described, which process comprises seeding a solution of sertraline free amine in a ketone with some crystals of polymorphic form II and addition of hydrogen chloride, and wherein the solution is heated before addition of the hydrogen chloride. According to the present process, the metastable form II may be obtained in a reliable way with good yield and high purity with respect to other polymorphic forms as well as preparative residues such as educts or solvents.
    Type: Application
    Filed: September 21, 2004
    Publication date: June 2, 2005
    Inventors: Paul Van Der Schaaf, Franz Schwarzenbach, Hans-Jorg Kirner, Martin Szelagiewicz, Claudia Marcolli, Andreas Burkhard
  • Publication number: 20050107359
    Abstract: The present invention is directed to the polymorphic Form B and the amorphous form of Benazepril hydrochloride. The present invention is also directed to processes for the preparation of Form B and the amorphous form of Benazepril hydrochloride, as well as novel processes for the preparation of Form A. Furthermore, the present invention is directed to pharmaceutical compositions comprising these crystalline forms.
    Type: Application
    Filed: July 17, 2003
    Publication date: May 19, 2005
    Inventors: Paul Van Der Schaaf, Claudia Marcolli, Fritz Blatter, Martin Szelagiewicz
  • Patent number: 6872853
    Abstract: A cystalline form of sertraline hydrochloride was found, referred to hereinafter as polymorphic form CSC2 having a dissolution rate which surprisingly will increase rate of absorption of a drug. Furthermore, different crystalline forms of sertraline hydrochloride alcohol solvates, crystalline forms of sertraline hydrochloride hydrates, referred to hereinafter as polymorphic form CSC1, a process for the preparation of the amorphous form of sertraline hydrochloride, and different processes for the preparation of polymorphic forms I, II, V, and T1 are disclosed.
    Type: Grant
    Filed: October 23, 2000
    Date of Patent: March 29, 2005
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Paul Adriaan Van Der Schaaf, Franz Schwarzenbach, Hans-Jörg Kirner, Martin Szelagiewicz, Claudia Marcolli, Andreas Burkhard, Regine Peter
  • Patent number: 6858643
    Abstract: Crystalline forms of the (3R,5S)- and the (3S,5R)-enantiomers of fluvastatin, referred to as polymorphic Forms A, B1, B2, C, D and E, processes for the preparation of these crystalline forms and pharmaceutical compositions comprising them are disclosed.
    Type: Grant
    Filed: October 23, 2001
    Date of Patent: February 22, 2005
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Paul Adriaan Van Der Schaaf, Heinz Wolleb, Annemarie Wolleb, Claudia Marcolli, Martin Szelagiewicz, Andreas Burkhard, Beat Freiermuth
  • Publication number: 20040239044
    Abstract: Device consisting of a support (1) and at least two seals (2), which are arranged in a row and are hermetically fitted into cavities, and protrude from the support laterally with respect to inlet and outlet openings, one end of the support being provided with an inlet opening (3) and one end being provided with an outlet opening (4), and the seals being provided with a least one inlet opening and one outlet opening, and the support containing at least one first channel (5) which starts at the inlet opening (3) and is continuous, and is arranged in such a way that it opens into the inlet openings in the side walls of the seals arranged in a row, and one second channel (6) which starts at the outlet opening and is continuous, and is arranged in such a way that it opens into the outlet openings in the side walls of the seals arranged in a row.
    Type: Application
    Filed: March 10, 2004
    Publication date: December 2, 2004
    Inventors: Fritz Blatter, Brigitte Cron-Eckhardt, Urs Christoph Hofmeier, Peter Koller, Claudia Marcolli, Martin Szelagiewicz
  • Publication number: 20040220255
    Abstract: The present invention is directed to new crystalline forms of Atorvastatin calcium (2:1), referred to hereinafter as polymorphic Forms X, A, B1, B2, C, D and E. Furthermore, the present invention is directed to processes for the preparation of these crystalline forms and pharmaceutical compositions comprising the crystalline forms.
    Type: Application
    Filed: June 2, 2004
    Publication date: November 4, 2004
    Inventors: Paul Adriaan Van Der Schaaf, Fritz Blatter, Martin Szelagiewicz, Kai-Uwe Schoning
  • Publication number: 20040167186
    Abstract: The invention relates to the novel modification A or A′ of the compound 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide of the formula 1
    Type: Application
    Filed: February 26, 2004
    Publication date: August 26, 2004
    Inventors: Robert Portmann, Urs Christoph Hofmeier, Andreas Burkhard, Walter Scherrer, Martin Szelagiewicz
  • Publication number: 20040132828
    Abstract: A crystalline form of sertraline hydrochloride was found, referred to hereinafter as polymorphic form CSC2 having a dissolution rate which surprisingly will increase rate of absorption of a drug.
    Type: Application
    Filed: December 15, 2003
    Publication date: July 8, 2004
    Inventors: Paul Adriaan Van Der Schaaf, Franz Schwarzenbach, Hans-Jorg Kirner, Martin Szelagiewicz, Claudia Marcolli, Andreas Burkhard, Regine Peter
  • Publication number: 20040106670
    Abstract: The present invention is directed to the novel polymorphic Form F of Atorvastatin calcium, processes for the preparation therof and pharmaceutical compositions comprising this crystalline form.
    Type: Application
    Filed: December 18, 2002
    Publication date: June 3, 2004
    Inventors: Fritz Blatter, Martin Szelagiewicz, Paul Adriaan Van Der Schaaf
  • Patent number: 6740669
    Abstract: The invention relates to the novel modification A or A′ of the compound 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide of the formula its use and pharmaceutical preparations comprising this crystal modification.
    Type: Grant
    Filed: September 8, 1998
    Date of Patent: May 25, 2004
    Assignee: Novartis AG
    Inventors: Robert Portmann, Urs Christoph Hofmeier, Andreas Burkhard, Walter Scherrer, Martin Szelagiewicz
  • Publication number: 20040063961
    Abstract: Crystalline forms of Cerivastatin sodium were found, referred to hereinafter as polymorphic Forms X, A1, A2, B, C, D1, D3, D4, E and F. Furthermore, the present invention is directed to processes for the preparation of these crystalline forms and pharmaceutical compositions comprising the crystalline forms.
    Type: Application
    Filed: June 19, 2003
    Publication date: April 1, 2004
    Inventors: Paul Adriaan Van Der Schaaf, Fritz Blatter, Martin Szelagiewicz, Nicole End
  • Patent number: 6696479
    Abstract: Novel crystalline forms of Fluvastatin sodium hydrates were found, referred to hereinafter as polymorphic Forms C, D, E and F. Furthermore, the present invention is directed to processes for the preparation of these crystalline forms, a process for the preparation of highly crystalline Fluvastatin sodium Form A, and pharmaceutical compositions comprising the crystalline forms.
    Type: Grant
    Filed: July 30, 2002
    Date of Patent: February 24, 2004
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Paul Adriaan Van Der Schaaf, Claudia Marcolli, Martin Szelagiewicz, Andreas Burkhard, Heinz Wolleb, Annemarie Wolleb
  • Publication number: 20030125569
    Abstract: Crystalline forms of the (3R,5S)- and the (3S,5R)-enantiomer of fluvastatin were found, referred to hereinafter as polymorphic Forms A, B1, B2, C, D and E. Furthermore, the present invention is directed to processes for the preparation of these crystalline forms and pharmaceutical compositions comprising the crystalline forms.
    Type: Application
    Filed: October 1, 2002
    Publication date: July 3, 2003
    Inventors: Paul Adriaan Van Der Schaaf, Heinz Wolleb, Annemarie Wolleb, Claudia Marcolli, Martin Szelagiewicz, Andreas Burkhard, Beat Freiermuth
  • Publication number: 20030125568
    Abstract: The invention relates to the novel modification A or A′ of the compound 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide of the formula 1
    Type: Application
    Filed: November 14, 2002
    Publication date: July 3, 2003
    Inventors: Robert Portmann, Urs Christoph Hofmeier, Andreas Burkhard, Walter Scherrer, Martin Szelagiewicz
  • Publication number: 20030114686
    Abstract: The present invention is directed to new crystalline forms of Atorvastatin calcium (2:1), referred to hereinafter as polymorphic Forms X, A, B1, B2, C, D and E. Furthermore, the present invention is directed to processes for the preparation of these crystalline forms and pharmaceutical compositions comprising the crystalline forms.
    Type: Application
    Filed: October 7, 2002
    Publication date: June 19, 2003
    Inventors: Paul Adriaan Van Der Schaaf, Fritz Blatter, Martin Szelagiewicz, Kai-Uwe Schoning
  • Publication number: 20030105359
    Abstract: Crystalline forms of Venlafaxine hydrochloride were found, referred to hereinafter as polymorphic Forms A, B and D. Furthermore, the present invention is directed to processes for the preparation of these crystalline forms and pharmaceutical compositions comprising the crystalline forms.
    Type: Application
    Filed: October 1, 2002
    Publication date: June 5, 2003
    Inventors: Paul Adriaan Van Der Schaaf, Claudia Marcolli, Martin Szelagiewicz, Beat Freiermuth
  • Publication number: 20030032666
    Abstract: Novel crystalline forms of Fluvastatin sodium hydrates were found, referred to hereinafter as polymorphic Forms C, D, E and F. Furthermore, the present invention is directed to processes for the preparation of these crystalline forms, a process for the preparation of highly crystalline Fluvastatin sodium Form A, and pharmaceutical compositions comprising the crystalline forms.
    Type: Application
    Filed: July 30, 2002
    Publication date: February 13, 2003
    Inventors: Paul Adriaan Van Der Schaaf, Claudia Marcolli, Martin Szelagiewicz, Andreas Burkhard, Heinz Wolleb, Annemarie Wolleb
  • Patent number: 6455556
    Abstract: The invention relates to the novel modifications B and C of the compound 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide of the formula their use and pharmaceutical preparations comprising this crystal modifications.
    Type: Grant
    Filed: May 31, 2001
    Date of Patent: September 24, 2002
    Assignee: Novartis AG
    Inventors: Robert Portmann, Urs Christoph Hofmeier, Andreas Burkhard, Walter Scherrer, Martin Szelagiewicz