Abstract: A system and method includes determination of a projection axis associated with the two-dimensional projection image, generation of a second two-dimensional image from the three-dimensional image based on the projection axis, registration of the two-dimensional projection image with the second two-dimensional image, combination of the registered two-dimensional projection image with the three-dimensional image in a plane of the three-dimensional image substantially orthogonal to the projection axis, and display of the combined image.

Abstract: A system and method includes detection of a trigger event, automatic injection, in response to detecting the trigger event, of a bolus of contrast medium into a patient volume after expiration of a predetermined injection delay period, automatic acquisition, in response to detecting the trigger event, of a plurality of images after expiration of a predetermined imaging delay period, where two or more of the plurality of images comprise an image of the bolus at respective different locations within vasculature of the patient volume, generation of a composite image based on the plurality of images, the composite image including a representation of the vasculature of the patient volume, and display of the composite image.

Abstract: A system and method includes determination of a projection axis associated with the two-dimensional projection image, generation of a second two-dimensional image from the three-dimensional image based on the projection axis, registration of the two-dimensional projection image with the second two-dimensional image, combination of the registered two-dimensional projection image with the three-dimensional image in a plane of the three-dimensional image substantially orthogonal to the projection axis, and display of the combined image.

Abstract: A system and method includes detection of a trigger event, automatic injection, in response to detecting the trigger event, of a bolus of contrast medium into a patient volume after expiration of a predetermined injection delay period, automatic acquisition, in response to detecting the trigger event, of a plurality of images after expiration of a predetermined imaging delay period, where two or more of the plurality of images comprise an image of the bolus at respective different locations within vasculature of the patient volume, generation of a composite image based on the plurality of images, the composite image including a representation of the vasculature of the patient volume, and display of the composite image.

Abstract: A system and method include reception of 3D imaging data showing blood flow over time in a patient volume including vessels, reception of a user input of a projection angle, generation of a plurality of 3D images based on the 3D imaging data, generation of a 2D digitally reconstructed radiograph (DRR) at the projection angle input by the user for one of the plurality of 3D X-ray images, and display of the 2D DRR image. Numerous other aspects are provided.

Abstract: A system and method includes detection of a trigger event, automatic injection, in response to detecting the trigger event, of a bolus of contrast medium into a patient volume after expiration of a predetermined injection delay period, automatic acquisition, in response to detecting the trigger event, of a plurality of images after expiration of a predetermined imaging delay period, where two or more of the plurality of images comprise an image of the bolus at respective different locations within vasculature of the patient volume, generation of a composite image based on the plurality of images, the composite image including a representation of the vasculature of the patient volume, and display of the composite image.

Abstract: A system and method includes reception of a plurality of fill frames of a patient volume, each of the plurality of fill frames depicting a contrast medium within the patient volume at a respective time, identification, for each pixel location of the fill frames, of a fill frame whose pixel at the pixel location is associated with a pixel value which represents a greater level of contrast medium than the pixel values of pixels at the pixel location within the others of the plurality of fill frames, generation of a peak contrast fill frame corresponding to each fill frame, the peak contrast fill frame corresponding to a given fill frame including, at pixel locations for which the given fill frame was identified, pixels associated with pixel values of the given fill frame, and storage of the plurality of peak contrast fill frames.

Abstract: A system and method includes reception of first two-dimensional projection images of a patient volume, each of the first two-dimensional projection images having been acquired from substantially a respective one of a plurality of projection angles during presence of at least a portion of contrast medium in arteries within the patient volume, reception of second two-dimensional projection images of the patient volume, each of the second two-dimensional projection images having been acquired from substantially a respective one of the plurality of projection angles during presence of at least a portion of the contrast medium in veins within the patient volume, generation, for each of the plurality of projection angles, of a composite two-dimensional image based on one of the first two-dimensional projection images acquired from substantially the projection angle and one of the second two-dimensional projection images acquired from substantially the projection angle, generation of a three-dimensional image based

Abstract: Embodiments relate to a method and system for calculating an optimal position for a valve clip to be placed and/or an optimal type of valve clip to be used for placement in a patient, based upon a simulation of the blood flow for the valve. Parameters that influence the simulation of blood flow for the mitral valve are used to conduct the simulation, the results of which are compared against certain predefined metrics. One or more metrics may be defined to analyze the effective regurgitation resulting from computational fluid dynamics (CFD) calculations. A valve clip and/or a clip position may be selected or determined to be preferred based upon flow characteristics calculated for the valve clip and/or the clip position under the CFD simulation. Appropriate instructions or other guidance information to appropriately place and affix the valve clip into the optimal position is provided via a user interface.

Abstract: A system and method includes reception of a plurality of fill frames of a patient volume, each of the plurality of fill frames depicting a contrast medium within the patient volume at a respective time, identification, for each pixel location of the fill frames, of a fill frame whose pixel at the pixel location is associated with a pixel value which represents a greater level of contrast medium than the pixel values of pixels at the pixel location within the others of the plurality of fill frames, generation of a peak contrast fill frame corresponding to each fill frame, the peak contrast fill frame corresponding to a given fill frame including, at pixel locations for which the given fill frame was identified, pixels associated with pixel values of the given fill frame, and storage of the plurality of peak contrast fill frames.

Abstract: A system and method includes detection of a trigger event, automatic injection, in response to detecting the trigger event, of a bolus of contrast medium into a patient volume after expiration of a predetermined injection delay period, automatic acquisition, in response to detecting the trigger event, of a plurality of images after expiration of a predetermined imaging delay period, where two or more of the plurality of images comprise an image of the bolus at respective different locations within vasculature of the patient volume, generation of a composite image based on the plurality of images, the composite image including a representation of the vasculature of the patient volume, and display of the composite image.

Abstract: A system and method includes reception of first two-dimensional projection images of a patient volume, each of the first two-dimensional projection images having been acquired from substantially a respective one of a plurality of projection angles during presence of at least a portion of contrast medium in arteries within the patient volume, reception of second two-dimensional projection images of the patient volume, each of the second two-dimensional projection images having been acquired from substantially a respective one of the plurality of projection angles during presence of at least a portion of the contrast medium in veins within the patient volume, generation, for each of the plurality of projection angles, of a composite two-dimensional image based on one of the first two-dimensional projection images acquired from substantially the projection angle and one of the second two-dimensional projection images acquired from substantially the projection angle, generation of a three-dimensional image based

Abstract: Embodiments relate to a method and system for calculating an optimal position for a valve clip to be placed and/or an optimal type of valve clip to be used for placement in a patient, based upon a simulation of the blood flow for the valve. Parameters that influence the simulation of blood flow for the mitral valve are used to conduct the simulation, the results of which are compared against certain predefined metrics. One or more metrics may be defined to analyze the effective regurgitation resulting from computational fluid dynamics (CFD) calculations. A valve clip and/or a clip position may be selected or determined to be preferred based upon flow characteristics calculated for the valve clip and/or the clip position under the CFD simulation. Appropriate instructions or other guidance information to appropriately place and affix the valve clip into the optimal position is provided via a user interface.

Abstract: A system and method include reception of 3D imaging data showing blood flow over time in a patient volume including vessels, reception of a user input of a projection angle, generation of a plurality of 3D images based on the 3D imaging data, generation of a 2D digitally reconstructed radiograph (DRR) at the projection angle input by the user for one of the plurality of 3D X-ray images, and display of the 2D DRR image. Numerous other aspects are provided.

Abstract: A method for visualizing a registration quality of medical image datasets is provided. A reference image and an object image are acquired and registered with each other to form a merged image by a registration method having a non-elastic and an elastic registration method section. A deformation field is determined having displacement vectors from image points of the object image to image points of the reference image which are conditioned by the elastic registration method section. One region of the merged image is overlayed with an overlay into which parameters of the deformation field are fed. The region of the merged image and the overlaid overlay is visualized.

Abstract: The invention relates to a method for selecting a volume of interest in one or more digitized images. A geometric structure in the digitized image for selecting a volume of interest is defined. A segmentation of the volume of interest in the digitized image is performed and visualized. The invention further relates to an apparatus, in particular a computer for performing the methods and a computer storage device comprising machine readable and executable program instructions which comprise steps of performing the methods. The invention can be applied for modern imaging developments, such as Computed Tomography, Angiography, and Magnetic Resonance Imaging which have made possible the acquisition of volumes where a volume of interest, e.g. the whole blood vessel tree, can be accurately visualized.