Patents by Inventor Martin von Janta-Lipinski

Martin von Janta-Lipinski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Beta-L-N4-Hydroxycytosine Deoxynucleosides and their use as Pharmaceutical Agents in the Prophylaxis or Therapy of Viral Diseases
    Publication number: 20090105186
    Abstract: The invention relates to ?-L-N4-hydroxycytosine nucleo-sides, pharmaceutical agents comprising same, and to the use of said ?-L-N4-hydroxycytosine nucleosides and pharmaceutical agents in the prophylaxis or therapy of an infection caused by hepatitis B virus (HBV) or human immunodeficiency virus (HIV). The invention also relates to a method for the preparation of said ?-L-nucleoside analogs.
    Type: Application
    Filed: October 21, 2005
    Publication date: April 23, 2009
    Applicant: MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN
    Inventors: Eckart Matthes, Martin von Janta-Lipinski, Hans Will, Huseyin Sirma, Anneke Funk
  • Chimeric oligonucleotides and the use thereof
    Publication number: 20010039263
    Abstract: The invention relates to novel chimeric oligonucleotides and their use, especially to bind and inhibit the enzyme telomerase. The oligonucleotides were prepared in view of RNA's non-binding activity to phosphorothioates and the primer binding site of the enzyme. The oligonucleotides bind to the primer binding site thereby resulting in maximum inhibition of the enzyme.
    Type: Application
    Filed: March 26, 2001
    Publication date: November 8, 2001
    Applicant: Max-Delbruck-Centrum fur Molekulare Medizin
    Inventors: Eckart Matthes, Martin Von Janta-Lipinski
  • 2',3'-dideoxynucleoside pyrimidine compounds and carbocyclic analogs
    Patent number: 5496935
    Abstract: 2',3'-dideoxynucleoside pyrimidine compounds and 2-thiothymidine carbocyclic derivatives with antiviral activity are disclosed. These compounds are expected to exhibit antiviral activity recognized for 2',3'-dideoxynucleoside compounds and analogs thereof.
    Type: Grant
    Filed: April 14, 1994
    Date of Patent: March 5, 1996
    Assignee: Max-Delbru/ ck-Centrum
    Inventors: Eckart Matthes, Martin von Janta-Lipinski, Dieter Scholz, Klaus Gaertner, Juergen Schildt, Christine Lehmann, Peter Langen, Hans A. Rosenthal
  • Fluorinated nucleosides and process for treating retrovirus infections therewith
    Patent number: 5153180
    Abstract: A process for treating AIDS, which comprises administering to a patient in need therefor a pharmaceutical composition comprising a therapeutically effective amount of a compound having the formula ##STR1## wherein: R.sub.1 is an adenine, cytosine, guanine, thymidine, uracil, 5-substituted uracil, 5-substituted cytosine derivative, 2-fluoroadenine, 2.6-diaminopurine, 2-aminopurine, 6-thioguanine, or 7-deazaadenine group;R.sub.2 is H, or a OH group;R.sub.3 is a OH, O-acyl, O-palmitoyl group or phosphates (as free acid, or its alkali, ammonium or alkyl ammonium salts), or any other precursor group for the hydroxyl group;or a physiologically acceptable salt thereof.
    Type: Grant
    Filed: August 13, 1990
    Date of Patent: October 6, 1992
    Inventors: Eckart Matthes, Christine Lehmann, Dieter Scholz, Martin von Janta-Lipinski, Klaus Gaertner, Peter Langen, Hans-Alfred Rosenthal
  • Fluorinated nucleosides and method for treating retrovirus infections therewith
    Patent number: 4963662
    Abstract: A method for treating AIDS, which comprises administering to a patient in need therefor a pharmaceutical composition comprising a therapeutically effective amount of a compound having the formula ##STR1## wherein R.sub.1 is an adenine, cytosine, guanine, thymidine, uracil, 5-substituted uracil, 5-substituted cytosine derivative, 2-fluoroadenine, 2.6-diaminopurine, 2-aminopurine, 6-thioguanine, or 7-deazaadenine group;R.sub.2 is H, or a OH group;R.sub.3 is a OH, O-acyl, O-palmitoyl group, or phosphates (as free acid, or its alkali, ammonium or alkyl ammonium salts), or any other precursor group for the hydroxyl group;or a physiologically acceptable salt thereof.
    Type: Grant
    Filed: July 15, 1988
    Date of Patent: October 16, 1990
    Assignee: Akademie der Wissenschaften der DDR
    Inventors: Eckart Matthes, Christine Lehmann, Dieter Scholz, Martin von Janta-Lipinski, Klaus Gaertner, Peter Langen, Hans-Alfred Rosenthal