Abstract: A post-operative pain inhibitor system comprises a controller and leads. Neuro-stimulator circuitry may be included within the patient controller or within one or more prosthetic components for generating a signal. In one example, a hip implant includes a prosthetic component having at least one electrode where the at least one electrode is configured to deliver energy pulses. Topical leads, percutaneous leads, subcutaneous leads, intraosseous leads, or leads can be placed in proximity to the operative field corresponding to the prosthetic component installation. The lead or electrodes can be coupled to neuro-stimulation circuitry to stimulate peripheral nerve fibers to affect body generated action potentials. A transmitter or power source can be housed in a prosthetic hip component. Controller can modify the pulse width, pulse shape, pulse repetition rate, and pulse amplitude of the signal thereby allowing the patient to adapt the signal to minimize their perceived pain.

Abstract: A post-operative pain inhibitor system comprises a controller and leads. Neuro-stimulator circuitry may be included within the patient controller or within one or more prosthetic components for generating a signal. In one example, an electrode is configured to be attached to skin in proximity to an operative field of an implanted joint. Topical leads, percutaneous leads, subcutaneous leads, intraosseous leads, or leads can also be placed in proximity to the operative field corresponding to the prosthetic component installation. The lead or electrodes can be coupled to neuro-stimulation circuitry to stimulate peripheral nerve fibers to affect body generated action potentials. A transmitter or power source can be housed in a prosthetic component. The controller can modify the pulse width, pulse shape, pulse repetition rate, and pulse amplitude of the signal thereby allowing the patient to adapt the signal to minimize their perceived pain.

Abstract: The invention provides a multilayer sleeve liner for application to the skin of a limb before applying a cast or brace. The liner is readily conformable to the limb configuration. It has a first layer that is applied to the skin. This has protective and cushioning functions. A second layer has a mesh structure that encircles the limb. It is constructed so that when its first end is pulled away from its second end, the encirclement of the limb is tightened. When one end of the mesh is attached to one end of the cast, and the other end is attached to another end of the cast, tension on the limb will tighten the liner. Without removing the cast, the liner may be adjusted by releasing one end of the mesh from the cast, and increasing or decreasing tension as necessary, then reattaching the mesh to the cast. A third layer may be provided to prevent adhesion of the cast to the liner.

Abstract: A post-operative pain inhibitor system (100) comprises a controller (32) and leads (25, 27). Neuro-stimulator circuitry may be included within the patient controller 32 or within one or more prosthetic components (12, 13, 14) for generating a signal. The topical leads (27), percutaneous leads (25), subcutaneous leads (26), intraosseous leads (22) or leads placed on or within prosthetic components are coupled to neuro-stimulation circuitry (44) to stimulate peripheral nerve fibers such that the signal blocks body generated action potentials. Controller (32) can modify the pulse width, pulse shape, pulse repetition rate, and pulse amplitude of the signal thereby allowing the patient to adapt the signal to minimize their perceived pain.

Abstract: At least one embodiment is directed to a system (400) to detect a presence of bacteria or other infecting organism in proximity to an implanted device. The system (400) comprises one or more biological sensors (412, 414, 416, 418) a processing unit (420), and a screen (422). Biological sensors (412, 414, 416, 418) detect a presence of bacteria or infecting organisms. Once an infection is detected, the system (400) can activate the release of anti-infective elements local to the implanted device. In one embodiment, nanostructures are used to retain the anti-infective elements until needed. A pulsed electrical field is applied in infected regions proximal to the implanted device. The pulsed electric field initiates electroporation allowing increased cell wall penetration of the anti-infective elements. The system (400) responds to an infection after surgical implantation and eradicates bacteria without the need for surgical intervention or implant removal.