Abstract: Embodiments are described of a computer-implemented method. The method receives a geometry of a design space for a design of a physical object based on one or more design parameters and a design objective subjected to design constraints and performs a plurality of topology optimizations according to the design objective to generate two or more structure configurations within the design space of the geometry based on two or more sets of values of the design parameters. Each structure configuration corresponds to a respective set of values of the design parameters.

Abstract: A vehicle interior component configured for response in event of a side impact may comprise an armrest assembly for a door panel. The armrest assembly may comprise a base section and an armrest section and a region configured for response to side impact at the door panel. The region may comprise a movable/deformable structure. Response of the armrest assembly may comprise deformation to partially absorb force and/or movement of the armrest section relative to the base section to partially cover the base section. The armrest assembly may comprise a carrier and/or mechanism to attach the armrest section to the door panel. The carrier/mechanism may be configured to guide/direct movement of the armrest section and/or to partially absorb the side impact force. The mechanism may comprise a set of pins movable within a set of slots to provide for movement of the armrest section.

Abstract: A control device for a first motorized pressure build-up device of a braking system of a vehicle. The control device is designed to output at least one first piece of information to an activation device of a second motorized pressure build-up device of the braking system by, under consideration of the respective first piece of information, a first motor activatable in such a way that a pressure prevailing in at least one partial volume of the braking system is varied in accordance with a pressure change signal, which is interpretable as the respective first piece of information for the activation device using a second pressure sensor unit of the second motorized pressure build-up device.

Abstract: An access device for a heart chamber, a removable hemostatic valve unit, and a system including a cardiac assist unit are disclosed. In examples, the access device) includes an apical base plate and a sealing unit configured to provide a separation of a wet zone from a heart chamber and a dry zone with a gaseous environment outside of said heart chamber inside a patient body at the same time.

Abstract: An access device for a heart chamber, a removable hemostatic valve unit, and a system including a cardiac assist unit are disclosed. In examples, the access device) includes an apical base plate and a sealing unit configured to provide a separation of a wet zone from a heart chamber and a dry zone with a gaseous environment outside of said heart chamber inside a patient body at the same time.

Abstract: An access device for a heart chamber, a removable hemostatic valve unit, and a system including a cardiac assist unit are disclosed. In examples, the access device) includes an apical base plate and a sealing unit configured to provide a separation of a wet zone from a heart chamber and a dry zone with a gaseous environment outside of said heart chamber inside a patient body at the same time.

Abstract: An access device for a heart chamber, a removable hemostatic valve unit, and a system including a cardiac assist unit are disclosed. In examples, the access device) includes an apical base plate and a sealing unit configured to provide a separation of a wet zone from a heart chamber and a dry zone with a gaseous environment outside of said heart chamber inside a patient body at the same time.

Abstract: An access device for a heart chamber, a removable hemostatic valve unit, and a system including a cardiac assist unit are disclosed. In examples, the access device) includes an apical base plate and a sealing unit configured to provide a separation of a wet zone from a heart chamber and a dry zone with a gaseous environment outside of said heart chamber inside a patient body at the same time.

Abstract: A control device for a first motorized pressure build-up device of a braking system of a vehicle. The control device is designed to output at least one first piece of information to an activation device of a second motorized pressure build-up device of the braking system by, under consideration of the respective first piece of information, a first motor activatable in such a way that a pressure prevailing in at least one partial volume of the braking system is varied in accordance with a pressure change signal, which is interpretable as the respective first piece of information for the activation device using a second pressure sensor unit of the second motorized pressure build-up device.

Abstract: An access device for a heart chamber, a removable hemostatic valve unit, and a system and a method of creating a transapical passage on a beating heart are disclosed. In examples, the access device (1) includes an apical base plate (100) and a sealing unit (3) configured to provide a separation of a wet zone from a heart chamber and a dry zone with a gaseous environment outside of said heart chamber inside a patient body at the same time.

Abstract: An at least partial annuloplasty ring for transcatheter cardiac valve treatment is disclosed. The annuloplasty ring has a plurality of separate chain segments serially interlinked and articulated to a chain. The chain has a substantially elongate delivery configuration and a curved deployment configuration. At least one of said chain segments has at least one tissue anchor attached to it, wherein the tissue anchor is movably arranged at least partly within the chain segment in the delivery configuration and protrudes from the chain segment in the deployment configuration in order to anchor with cardiac tissue.

Abstract: The invention relates to a polyamide polymer; to a polymer composition comprising the polyamide polymer and a fibrous reinforcing agent or a filler, or a combination thereof; to a molded part made of the polymer composition; and to an automotive vehicle comprising a load-bearing structural part made of the molded part. Herein the polyamide polymer has a glass transition temperature (Tg) of at least 145° C. and a dynamic modulus (E?), measured at a temperature (Tmod) equal to Tg+15° C., in the range of 100 MPa-700 MPa.

Abstract: An implantable medical device for transcatheter delivery is disclosed including: an anchor unit configured to be permanently anchored at a cardiac valve of a patient. At least one locking unit is provided for fixation of tissue of the cardiac valve and/or fixation of at least a part of a shape of the anchor unit and/or for connection to a further unit via the at least one coupling unit. The further unit is preferably a cardiac valve replacement or repair unit and/or a driving unit such as of a cardiac assist device. The device further includes at least one coupling unit of fixed permanent length or non-reversibly adjustable length before locking the coupling unit to the fixed permanent length for connecting the anchor unit to at least one of the locking unit. The coupling unit has a first end portion and a second end portion. The first end portion is connectable to the anchor unit, and the second end portion includes the locking unit.

Abstract: An implantable medical device for transcatheter delivery is disclosed including: an anchor unit configured to be permanently anchored at a cardiac valve of a patient. At least one locking unit is provided for fixation of tissue of the cardiac valve and/or fixation of at least a part of a shape of the anchor unit and/or for connection to a further unit via the at least one coupling unit. The further unit is preferably a cardiac valve replacement or repair unit and/or a driving unit such as of a cardiac assist device. The device further includes at least one coupling unit of fixed permanent length or non-reversibly adjustable length before locking the coupling unit to the fixed permanent length for connecting the anchor unit to at least one of the locking unit. The coupling unit has a first end portion and a second end portion. The first end portion is connectable to the anchor unit, and the second end portion includes the locking unit.

Abstract: An implantable medical device for transcatheter delivery is disclosed including: an anchor unit configured to be permanently anchored at a cardiac valve of a patient. At least one locking unit is provided for fixation of tissue of the cardiac valve and/or fixation of at least a part of a shape of the anchor unit and/or for connection to a further unit via the at least one coupling unit. The further unit is preferably a cardiac valve replacement or repair unit and/or a driving unit such as of a cardiac assist device. The device further includes at least one coupling unit of fixed permanent length or non-reversibly adjustable length before locking the coupling unit to the fixed permanent length for connecting the anchor unit to at least one of the locking unit. The coupling unit has a first end portion and a second end portion. The first end portion is connectable to the anchor unit, and the second end portion includes the locking unit.

Abstract: An implantable medical device is disclosed including an anchor unit configured to be permanently anchored at a cardiac valve of a patient, at least one locking unit, such as for fixation of tissue of the cardiac valve and/or fixation of at least a part of a shape of the anchor unit, and at least one coupling unit for connecting the anchor unit to at least one of the locking unit. The coupling unit has a first end portion and a second end portion, wherein the first end portion is connectable to the anchor unit, and the second end portion includes the locking unit.

Abstract: An at least partial annuloplasty ring for transcatheter cardiac valve treatment is disclosed. The annuloplasty ring has a plurality of separate chain segments serially interlinked and articulated to a chain. The chain has a substantially elongate delivery configuration and a curved deployment configuration. At least one of said chain segments has at least one tissue anchor attached to it, wherein the tissue anchor is movably arranged at least partly within the chain segment in the delivery configuration and protrudes from the chain segment in the deployment configuration in order to anchor with cardiac tissue.

Abstract: An implantable medical device is disclosed including an anchor unit configured to be permanently anchored at a cardiac valve of a patient, at least one locking unit, such as for fixation of tissue of the cardiac valve and/or fixation of at least a part of a shape of the anchor unit, and at least one coupling unit for connecting the anchor unit to at least one of the locking unit. The coupling unit has a first end portion and a second end portion, wherein the first end portion is connectable to the anchor unit, and the second end portion includes the locking unit.

Abstract: The present invention relates to a semi-crystalline semi-aromatic polyamide consisting of 95-100 mole % of monomeric units derived from diamine comprising aliphatic diamine comprising 5-40 mole % of a cycloaliphatic diamine, and dicarboxylic acid comprising at least 50 mole % of naphthalene dicarboxylic acid (N), or biphenyl dicarboxylic acid (B), or a combination thereof.

Abstract: The invention relates to a process for the preparation of a PA XY/XZ polyamide, more particular a copolyamide having alternating XY units and XZ units and a process for the manufacture thereof. Further, the present invention relates to compositions and articles comprising said copolyamide. Furthermore, the present invention relates to diamines and salts which are intermediary products of the process for the manufacture of said copolyamide.