Patents by Inventor Martina Delbeck

Martina Delbeck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted perhydropyrrolo[3,4-c]pyrrole derivatives and the use of same
    Patent number: 10414765
    Abstract: The present application relates to novel (2-phenylimidazo[1,2-a]pyridin-3-yl)methyl-substituted perhydropyrrolo[3,4-c]pyrrole derivatives, to methods for the preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of respiratory disorders including sleep-related respiratory disorders such as obstructive sleep apneas and central sleep apneas and snoring.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: September 17, 2019
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Martina Delbeck, Michael Hahn, Thomas Müller, Heinrich Meier, Klemens Lustig, Johanna Mosig, Luisella Toschi, Udo Albus, Doris Gehring, Björn Rosenstein
  • 2-PHENYL-3-(PIPERAZINOMETHYL)IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS BLOCKERS OF TASK-1 AND TASK-2 CHANNELS, FOR THE TREATMENT OF SLEEP-RELATED BREATHING DISORDERS
    Publication number: 20190062326
    Abstract: The present application relates to novel 2-phenyl-3-(piperazinomethyl)imidazo[1,2-a]pyridine derivatives, to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases, and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for treatment and/or prevention of respiratory disorders including, sleep-related respiratory disorders such as obstructive sleep apnoeas and central sleep apnoeas and snoring.
    Type: Application
    Filed: December 7, 2016
    Publication date: February 28, 2019
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Martina DELBECK, Michael HAHN, Thomas MÜLLER, Heinrich MEIER, Klemens LUSTIG, Johanna MOSIG, Luisella TOSCHI, Udo ALBUS, Doris GEHRING, Björn ROSENSTEIN
  • Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents
    Patent number: 10189788
    Abstract: The present application relates to novel substituted N,2-diarylquinoline-4-carboxamide derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of fibrotic and/or inflammatory disorders.
    Type: Grant
    Filed: September 7, 2015
    Date of Patent: January 29, 2019
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Hartmut Beck, Tobias Thaler, Raimund Kast, Daniel Meibom, Mark Meininghaus, Carsten Terjung, Martina Delbeck, Klemens Lustig, Uwe Muenster, Britta Olenik
  • SUBSTITUTED N,2-DIARYLQUINOLINE-4-CARBOXAMIDES AND THE USE THEREOF AS ANTI-INFLAMMATORY AGENTS
    Publication number: 20190002409
    Abstract: The present application relates to novel substituted N,2-diarylquinoline-4-carboxamide derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of fibrotic and/or inflammatory disorders.
    Type: Application
    Filed: September 7, 2018
    Publication date: January 3, 2019
    Inventors: Hartmut BECK, Tobias THALER, Raimund KAST, Daniel MEIBOM, Mark MEININGHAUS, Carsten TERJUNG, Martina DELBECK, Klemens LUSTIG, Uwe MUENSTER, Britta OLENIK
  • SUBSTITUTED PERHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AND THE USE OF SAME
    Publication number: 20180370965
    Abstract: The present application relates to novel (2-phenylimidazo[1,2-a]pyridin-3-yl)methyl-substituted perhydropyrrolo[3,4-c]pyrrole derivatives, to methods for the preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of respiratory disorders including sleep-related respiratory disorders such as obstructive sleep apneas and central sleep apneas and snoring.
    Type: Application
    Filed: December 2, 2016
    Publication date: December 27, 2018
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Martina DELBECK, Michael HAHN, Thomas MÜLLER, Heinrich MEIER, Klemens LUSTIG, Johanna MOSIG, Luisella TOSCHI, Udo ALBUS, Doris GEHRING, Björn ROSENSTEIN
  • 5-aminotetrahydroquinoline-2-carboxylic acids and their use
    Patent number: 10053428
    Abstract: The present application relates to novel 5-amino-5,6,7,8-tetrahydroquinoline-2-carboxylic acids, to processes for their preparation, to their use for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular and cardiopulmonary disorders.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: August 21, 2018
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Michael Hahn, Markus Follmann, Eva-Maria Becker, Johannes-Peter Stasch, Joerg Keldenich, Martina Delbeck, Hanna Tinel, Frank Wunder, Joachim Mittendorf, Ildiko Terebesi, Dieter Lang, René Martin, Walter Hübsch
  • Use of cathepsin K inhibition for the treatment and/or prophylaxis of pulmonary hypertension and/or heart failure
    Patent number: 9943522
    Abstract: The present invention relates to the use of cathepsin K and/or cathepsin S inhibitors in a method for the treatment and/or prophylaxis of pulmonary hypertension and/or heart failure.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: April 17, 2018
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Stefan Golz, Martina Delbeck, Heinrich Meier, Andreas Geerts, Thomas Mondritzki, Hubert Trübel
  • HETEROCYCLYLMETHYL-THIENOURACILE AS ANTAGONISTS OF THE ADENOSINE-A2B-RECEPTOR
    Publication number: 20180065981
    Abstract: The present application relates to novel thieno[2,3-d]pyrimidine-2,4-dione (“thienouracil”) derivatives bearing a particular type of (azaheterocyclyl)methyl substituent, to processes for the preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of pulmonary and cardiovascular disorders and of cancer.
    Type: Application
    Filed: March 21, 2016
    Publication date: March 8, 2018
    Inventors: Michael HÄRTER, Dirk KOSEMUND, Martina DELBECK, Bernd KALTHOF, Pierre WASNAIRE, Frank SÜßMEIER, Klemens LUSTIG
  • SUBSTITUTED N,2-DIARYLQUINOLINE-4-CARBOXAMIDES AND THE USE THEREOF AS ANTI-INFLAMMATORY AGENTS
    Publication number: 20170260140
    Abstract: The present application relates to novel substituted N,2-diarylquinoline-4-carboxamide derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of fibrotic and/or inflammatory disorders.
    Type: Application
    Filed: September 7, 2015
    Publication date: September 14, 2017
    Applicant: Bayer Pharma Aktiengesekkschaft
    Inventors: Hartmut BECK, Tobias THALER, Raimund KAST, Daniel MEIBOM, Mark MEININGHAUS, Carsten TERJUNG, Martina DELBECK, Klemens LUSTIG, Uwe MUENSTER, Britta OLENIK
  • NOVEL 5-AMINOTETRAHYDROQUINOLINE-2-CARBOXYLIC ACIDS AND THEIR USE
    Publication number: 20170260139
    Abstract: The present application relates to novel 5-amino-5,6,7,8-tetrahydroquinoline-2-carboxylic acids, to processes for their preparation, to their use for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular and cardiopulmonary disorders.
    Type: Application
    Filed: May 19, 2017
    Publication date: September 14, 2017
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: MICHAEL HAHN, MARKUS FOLLMANN, EVA-MARIA BECKER, JOHANNES-PETER STASCH, JOERG KELDENICH, MARTINA DELBECK, HANNA TINEL, FRANK WUNDER, JOACHIM MITTENDORF, ILDIKO TEREBESI, DIETER LANG, RENÉ MARTIN, WALTER HÜBSCH
  • 5-aminotetrahydroquinoline-2-carboxylic acids and their use
    Patent number: 9688636
    Abstract: The present application relates to novel 5-amino-5,6,7,8-tetrahydroquinoline-2-carboxylic acids, to processes for their preparation, to their use for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular and cardiopulmonary disorders.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: June 27, 2017
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Michael Hahn, Markus Follmann, Walter Hübsch, Eva-Maria Becker, Johannes-Peter Stasch, Joerg Keldenich, Martina Delbeck, Hanna Tinel, Frank Wunder, Joachim Mittendorf, Ildiko Terebesi, Dieter Lang, René Martin
  • Bisaryl-bonded aryltriazolones and use thereof
    Patent number: 9687476
    Abstract: The present application relates to novel bisaryl-linked 5-aryl-1,2,4-triazolone derivatives, to processes for preparing them, to their use alone or in combinations for the treatment and/or prevention of diseases and also to their use for the production of medicaments for the treatment and/or prevention of diseases, more particularly for the treatment and/or prevention of cardiovascular disorders.
    Type: Grant
    Filed: November 2, 2015
    Date of Patent: June 27, 2017
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Chantal Fürstner, Jörg Keldenich, Martina Delbeck, Peter Kolkhof, Axel Kretschmer, Ingo Pluschkell, Elisabeth Pook, Carsten Schmeck, Hubert Trübel
  • CYCLIC THIENOURACIL-CARBOXAMIDES AND USE THEREOF
    Publication number: 20170145029
    Abstract: The present application relates to novel 2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxamide derivatives (“thienouracil”-carboxamides), to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases and to their use for the preparation of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of pulmonary and cardiovascular disorders.
    Type: Application
    Filed: February 2, 2017
    Publication date: May 25, 2017
    Inventors: Michael HÄRTER, Martina DELBECK, Bernd KALTHOF, Klemens LUSTIG, Niels LINDNER, Raimund KAST, Pierre WASNAIRE, Frank SÜßMEIER
  • Cyclic thienouracil-carboxamides and use thereof
    Patent number: 9604996
    Abstract: The present application relates to novel 2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxamide derivatives (“thienouracil”-carboxamides), to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases and to their use for the preparation of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of pulmonary and cardiovascular disorders.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: March 28, 2017
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Michael Härter, Martina Delbeck, Bernd Kalthof, Klemens Lustig, Niels Lindner, Raimund Kast, Pierre Wasnaire, Frank Süβmeier
  • CYCLIC THIENOURACIL-CARBOXAMIDES AND USE THEREOF
    Publication number: 20160244461
    Abstract: The present application relates to novel 2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxamide derivatives (“thienouracil”-carboxamides), to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases and to their use for the preparation of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of pulmonary and cardiovascular disorders.
    Type: Application
    Filed: October 2, 2014
    Publication date: August 25, 2016
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Michael HÄRTER, Martina DELBECK, Bernd KALTHOF, Klemens LUSTIG, Niels LINDNER, Raimund KAST, Pierre WASNAIRE, Frank SÜßMEIER
  • Triazolo and tetrazolo pyrimidine derivatives as HNE inhibitors for treating COPD
    Patent number: 9359362
    Abstract: The present invention relates to novel heterocyclically fused diaryldihydropyrimidine derivatives, to processes for their preparation, to their use alone or in combination for the treatment and/or prevention of diseases and also to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of disorders of the lung and the cardiovascular system.
    Type: Grant
    Filed: October 7, 2013
    Date of Patent: June 7, 2016
    Assignee: Bayer Intellectual Property Gmbh
    Inventors: Franz Von Nussbaum, Dagmar Karthaus, Sonja Anlauf, Martina Delbeck, Volkhart Min-Jian Li, Daniel Meibom, Klemens Lustig
  • BISARYL-BONDED ARYLTRIAZOLONES AND USE THEREOF
    Publication number: 20160051518
    Abstract: The present application relates to novel bisaryl-linked 5-aryl-1,2,4-triazolone derivatives, to processes for preparing them, to their use alone or in combinations for the treatment and/or prevention of diseases and also to their use for the production of medicaments for the treatment and/or prevention of diseases, more particularly for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: November 2, 2015
    Publication date: February 25, 2016
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Chantal FÜRSTNER, Jörg KELDENICH, Martina DELBECK, Peter KOLKHOF, Axel KRETSCHMER, Ingo PLUSCHKELL, Elisabeth POOK, Carsten SCHMECK, Hubert TRÜBEL
  • Bisaryl-bonded aryltriazolones and use thereof
    Patent number: 9187466
    Abstract: The present invention relates to bisaryl-linked 5-aryl-1,2,4-triazolone derivatives according to the following formula: wherein Ar1, Ar2, R1, R2, L1, L2, Q and n are defined herein. The invention further related to the process of making the bisaryl-linked 5-aryl-1,2,4-triazolone derivatives.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: November 17, 2015
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Chantal Furstner, Joerg Keldenich, Martina Delbeck, Peter Kolkhof, Axel Kretschmer, Ingo Pluschkell, Elisabeth Pook, Carsten Schmeck, Hubert Trubel
  • Substituted -phenethyltriazoloneacetamides and use thereof
    Patent number: 9180120
    Abstract: The present application relates to novel substituted N-phenethyltriazoloneacetamides, to processes for preparing them, to their use alone or in combinations for the treatment and/or prevention of diseases and also to their use for the production of medicaments for the treatment and/or prevention of diseases, more particularly for the treatment and/or prevention of cardiovascular disorders.
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: November 10, 2015
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Chantal Fürstner, Joerg Keldenich, Martina Delbeck, Peter Kolkhof, Axel Kretschmer, Elisabeth Pook, Carsten Schmeck, Hubert Trübel
  • 4-(4-cyano-2-thioaryl)dihydropyrimidinones and use thereof
    Patent number: 9174997
    Abstract: The present invention relates to novel 4-(4-cyano-2-thioaryl)dihydropyrimidin-2-one derivatives, to processes for their preparation, to their use alone or in combination for the treatment and/or prevention of diseases and also to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of disorders of the lung and the cardiovascular system.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: November 3, 2015
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Franz Von Nussbaum, Dagmar Karthaus, Sonja Anlauf, Martina Delbeck, Volkhart Min-Jian Li, Daniel Meibom, Klemens Lustig, Jens Schamberger