Patents by Inventor Martina Hensel

Martina Hensel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Group of novel enantioselective microbial nitrile hydratases with broad substrate specificity
    Patent number: 8470576
    Abstract: The present invention provides a polynucleotide or a pair of polynucleotides encoding an enzyme having nitrile hydratase (NHase) [E.C. 4.2.1.84] activity. Furthermore, a vector and a host comprising the disclosed polynucleotide or pair of polynucleotides and methods for the production of the same are provided. Moreover, the invention relates to a pair of polypeptides or a fusion protein having NHase activity, an antibody specifically binding to the pair of polypeptides or fusion protein, a primer or probe, which specifically hybridizes under stringent conditions to the disclosed polynucleotide or either one of the pair of polynucleotides, a composition comprising the polynucleotide or pair of polynucleotides, the pair of polypeptides or fusion protein, the antibody and/or one or more primers or probes of the invention and a method for the production of amides comprising the enantioselective conversion of nitriles.
    Type: Grant
    Filed: April 5, 2007
    Date of Patent: June 25, 2013
    Assignee: B.R.A.I.N. AG
    Inventors: Jürgen Eck, Klaus Liebeton, Lutz Fischer, Sabine Lutz-Wahl, Martina Hensel, Christian Ewert, Marcus Wälz
  • GROUP OF NOVEL ENANTIOSLEECTIVE MICROBIAL NITRILE HYDRATASES WITH BROAD SUBSTRATE SPECIFICITY
    Publication number: 20100047863
    Abstract: The present invention provides a polynucleotide or a pair of polynucleotides encoding an enzyme having nitrile hydratase (NHase) [E.C. 4.2.1.84] activity. Furthermore, a vector and a host comprising the disclosed polynucleotide or pair of polynucleotides and methods for the production of the same are provided. Moreover, the invention relates to a pair of polypeptides or a fusion protein having NHase activity, an antibody specifically binding to the pair of polypeptides or fusion protein, a primer or probe, which specifically hybridizes under stringent conditions to the disclosed polynucleotide or either one of the pair of polynucleotides, a composition comprising the polynucleotide or pair of polynucleotides, the pair of polypeptides or fusion protein, the antibody and/or one or more primers or probes of the invention and a method for the production of amides comprising the enantioselective conversion of nitrites.
    Type: Application
    Filed: April 5, 2007
    Publication date: February 25, 2010
    Applicant: B.R.A.I.N. AG
    Inventors: Jürgen Eck, Klaus Liebeton, Lutz Fischer, Sabine Lutz-Wahl, Martina Hensel, Christian Ewert, Marcus Wälz