Patents by Inventor Martina Hermannova

Martina Hermannova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DENTAL PREPARATION COMPRISING FIBERS BASED ON HYALURONIC ACID WITH REGULATED BIODEGRADABILITY
    Publication number: 20230069878
    Abstract: A biodegradable dental preparation comprising at least one water-soluble fiber from hyaluronic acid or a physiologically acceptable salt thereof and at least one fiber from a non-polar derivative of hyaluronic acid is disclosed. The dental preparation may comprise an antimicrobial agent. The dental preparation may be useful in the treatment of periodontal disease or in the treatment of injuries in the periodontium and oral mucosa. Methods of preparing the dental preparations, fibers thereof, and related compositions thereto, are also disclosed.
    Type: Application
    Filed: January 5, 2021
    Publication date: March 9, 2023
    Applicant: CONTIPRO A.S.
    Inventors: Tomas PITUCHA, Jakub SUCHANEK, Kristyna CHMELICKOVA, Lucie HORACKOVA, Jana MATONOHOVA, Tomas MEDEK, Jozef ROSA, Romana SULAKOVA, Lida GRUSOVA, Radovan BUFFA, Martina HERMANNOVA, Jarmila HUSBY, Vladimir VELEBNY
  • Chlorinated derivative of hyaluronic acid, method of preparation thereof, a composition containing the derivative, and use thereof
    Patent number: 11427652
    Abstract: A chlorinated derivative of hyaluronic acid or of a modified hyaluronic acid (chloramide) is provided. The chloramide has an amidic group (—NH—CO—). The hydrogen of the amidic group is substituted by a chlorine atom, according to the structural formula —NCl—CO—. The substitution degree of the hyaluronic acid or of the modified hyaluronic acid by chlorine is in an amount of from 50 to 100 %.
    Type: Grant
    Filed: August 17, 2019
    Date of Patent: August 30, 2022
    Assignee: CONTIPRO A.S.
    Inventors: Radovan Buffa, Ivana Basarabova, Martina Hermannova, Katerina Knotkova, Jaromir Kulhanek, Josef Chmelar, Tomá{hacek over (s)} Pitucha, Drahomira Chladkova, Helena Krejci, Hana Vagnerova, Martin Sojka, Lubos Sobotka, Vladimir Velebny
  • CHLORINATED DERIVATIVE OF HYALURONIC ACID, METHOD OF PREPARATION THEREOF, A COMPOSITION CONTAINING THE DERIVATIVE, AND USE THEREOF
    Publication number: 20210332161
    Abstract: A chlorinated derivative of hyaluronic acid or of a modified hyaluronic acid (chloramide) is provided. The chloramide has an amidic group (—NH—CO—). The hydrogen of the amidic group is substituted by a chlorine atom, according to the structural formula —NCl—CO—. The substitution degree of the hyaluronic acid or of the modified hyaluronic acid by chlorine is in an amount of from 50 to 100 %.
    Type: Application
    Filed: August 17, 2019
    Publication date: October 28, 2021
    Inventors: Radovan BUFFA, Ivana BASARABOVA, Martina HERMANNOVA, Katerina KNOTKOVA, Jaromir KULHANEK, Josef CHMELAR, Tomás PITUCHA, Drahomira CHLADKOVA, Helena KREJCI, Hana VAGNEROVA, Martin SOJKA, Lubos SOBOTKA, Vladimir VELEBNY
  • Fluorescent Cypate Conjugate of Hyaluronic Acid or Salt Thereof, Hydrophobized Conjugate, Methods of Preparation and Use Thereof
    Publication number: 20190001000
    Abstract: The present invention relates to the fluorescent conjugate of hyaluronic acid containing cypate or salts thereof, the hydrophobized conjugate, methods of the preparation and use thereof in medicinal applications for in vivo imaging and the treatment of neoplasms.
    Type: Application
    Filed: December 22, 2016
    Publication date: January 3, 2019
    Inventors: Eva Achbergerova, Daniela Smejkalova, Gloria Huerta-Angeles, Karel Soucek, Martina Hermannova, Vladimir Velebny
  • C-C-acylated derivative of hyaluronic acid and method of preparation thereof
    Patent number: 9999678
    Abstract: The invention relates to a method of preparation hydrophobized hyaluronic acid (Formula I) and further to a method of encapsulating biologically active substances into the nanomicelles of hydrophobized hyaluronan serving as carriers of biologically active hydrophobic substances. The hydrophobization of hyaluronan is carried out through an esterification reaction of hyaluronan with long-chain carboxylic acids, the latter being activated by a halogenide derivative of 2,4,6-trichlorobenzoic acid or by another organic chloride. In an aqueous environment, water-soluble hydrophobized derivatives can form nanomicelles in which nonpolar substances can be bound by means of non-covalent physical interactions. The core of a nanomicelle is formed by hydrophobic acyl functional groups while the shell of a nanomicelle is formed by hyaluronic acid. The encapsulation of the substances into nanomicelles can be performed by means of the solvent exchange method or by means of sonication.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: June 19, 2018
    Assignee: Contipro a.s.
    Inventors: Daniela Smejkalova, Gloria Huerta-Angeles, Martin Bobek, Martina Hermannova, Lucie Vistejnova, Jaroslav Novotny, Eva Prikopova, Kristina Nesporova, Miroslava Nemcova, Klara Slezingrova, Jaromir Kulhanek, Dagmar Cozikova, Jana Sogorkova, Jan Kucera, Pavel Klein, Vladimir Velebny
  • C6-C18-Acylated Derivative of Hyaluronic Acid, Method of Preparation Thereof, Nanomicellar Composition on its Basis, Method of Preparation Thereof and Method of Preparation Stabilized Nanomicellar Composition, and Use Thereof
    Publication number: 20150320873
    Abstract: The invention relates to a method of preparation hydrophobized hyaluronic acid (Formula I) and further to a method of encapsulating biologically active substances into the nanomicelles of hydrophobized hyaluronan serving as carriers of biologically active hydrophobic substances. The hydrophobization of hyaluronan is carried out through an esterification reaction of hyaluronan with long-chain carboxylic acids, the latter being activated by a halogenide derivative of 2,4,6-trichlorobenzoic acid or by another organic chloride. In an aqueous environment, water-soluble hydrophobized derivatives can form nanomicelles in which nonpolar substances can be bound by means of non-covalent physical interactions. The core of a nanomicelle is formed by hydrophobic acyl functional groups while the shell of a nanomicelle is formed by hyaluronic acid. The encapsulation of the substances into nanomicelles can be performed by means of the solvent exchange method or by means of sonication.
    Type: Application
    Filed: November 26, 2013
    Publication date: November 12, 2015
    Inventors: Daniela Smejkalova, Gloria Huerta-Angeles, Martin Bobek, Martina Hermannova, Lucie Vistejnova, Jaroslav Novotny, Eva Prikopova, Kristina Nesporova, Miroslava Nemcova, Klara Slezingrova, Jaromir Kulhanek, Dagmar Cozikova, Jana Sogorkova, Jan Kucera, Pavel Klein, Vladimir Velebny