Patents by Inventor Martina Junius-Comer

Martina Junius-Comer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Redox-active compounds and their use
    Patent number: 6057120
    Abstract: The invention concerns the use of redox-active compounds for the production of detection reagents for a method for the determination of an analyte as well as reagent kits that contain these redox-active compounds. In addition new redox-active compounds are disclosed.
    Type: Grant
    Filed: September 22, 1997
    Date of Patent: May 2, 2000
    Assignee: Roche Diagnostics GmbH
    Inventors: Dieter Heindl, Rupert Herrmann, Joachim Hones, Hans-Peter Josel, Martina Junius-Comer, Hartmut Merdes, Axel Schmidt, Ernst Selbertinger
  • Stabilization of bilirubin in control sera and calibrators
    Patent number: 5854073
    Abstract: The invention concerns a stable control serum or calibration serum containing bilirubin to analytically examine the methodical accuracy of individual parameters in human sera or patients. The control serum or calibration serum according to the invention is used to stabilize bilirubin in solutions and to generally increase the stability of control sera or calibration sera.
    Type: Grant
    Filed: March 21, 1997
    Date of Patent: December 29, 1998
    Assignee: Bohringer Mannheim GmbH
    Inventors: Geoffrey Burns, Martina Junius-Comer
  • Indophenol substituted maltooligosides as .alpha.-amylase substrates
    Patent number: 5654163
    Abstract: The invention concerns new indophenyl-substituted maltose derivatives, their use for the determination of the enzymatic activity of .alpha.-amylase and reagents for the determination of .alpha.-amylase which contain the new indophenyl-substituted maltose derivatives as the enzyme substrate.
    Type: Grant
    Filed: July 24, 1995
    Date of Patent: August 5, 1997
    Assignee: Boehringer Mannheim GmbH
    Inventors: Martina Junius-Comer, Axel Schmidt, Elli Rauscher
  • Process for the determination of phospholipase A in body fluids
    Patent number: 5244789
    Abstract: The present invention provides a process for the determination of phospholipase A in body fluids, wherein the body fluid is incubated with a mixture containing a substrate having a fatty acid residue for the phospholipase and at least two emulsifiers of different chemical classes, namely, at least one neutral emulsifier and a bile acid salt, and the amount of the free fatty acids formed by the cleavage of the substrate is determined in known manner.
    Type: Grant
    Filed: September 9, 1991
    Date of Patent: September 14, 1993
    Assignee: Boehringer Mannheim GmbH
    Inventors: Ulrich Neumann, Gudrun Schmidt, Martina Junius-Comer
  • Substituted phenols
    Patent number: 5204242
    Abstract: The present invention provides a colorimetric process for the detection of an oxidative coupling reaction in which a coupling component is reacted with a developer component in the presence of an oxidation agent to give a colored material, wherein, as coupling component, there is used a compound of the general formula: ##STR1## in which X is a bromine or chlorine atom, n is 1, 2 or 3, Y is COOR, CONRR', SO.sub.3 R, SO.sub.2 NRR', OR, NRR' or NRR'R".sym. and R, R' and R", independently of one another, are hydrogen atoms or C.sub.1 -C.sub.3 -alkyl radicals.The present invention also provides a reagent which contains the above compound, as well as new substituted phenols and a process for the preparation thereof.
    Type: Grant
    Filed: September 17, 1991
    Date of Patent: April 20, 1993
    Assignee: Boehringer Mannheim GmbH
    Inventors: Martina Junius-Comer, Bernd Vogt, Rupert Herrmann
  • Method for increasing the enzymatic reactivity of .beta.-galactosidase by addition of a cyanate, thiocyanate, azide, or thiosulfate compound
    Patent number: 5194382
    Abstract: In order to increase the enzymatic reactivity of .beta.-galactosidase, an azide, thiocyanate, cyanate and/or thiosulphate is added to the reaction mixture.
    Type: Grant
    Filed: November 5, 1990
    Date of Patent: March 16, 1993
    Assignee: Boehringer Mannheim GmbH
    Inventors: Rupert Herrmann, Hans-Joachim Guder, Martina Junius-Comer