Patents by Inventor Martina Malatesta

Martina Malatesta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING PROSTATE CANCER
    Publication number: 20230241063
    Abstract: The present application relates generally to methods for treating prostate cancer with a lysine specific demethylase-1 (LSD-1) inhibitor, wherein the lysine specific demethylase-1 (LSD-1) inhibitor resensitizes the prostate cancer cells to androgen receptor pathway inhibitor (ARPI) treatment.
    Type: Application
    Filed: June 4, 2021
    Publication date: August 3, 2023
    Applicant: Celgene Quanticel Research, Inc.
    Inventors: JUAN DE ALVARO, JOSEP LLUIS PARRA-PALAU, ZARIANA NIKOLOVA, JORGE DI MARTINO, ELLEN FILVAROFF, IDA ARONCHIK, MARTINA MALATESTA
  • COMPOSITIONS AND METHODS OF TREATING GLIOMA
    Publication number: 20230193250
    Abstract: The present disclosure relates generally to detection of long noncoding RNA (lncRNA) molecules in a sample or diagnosis of subject based upon detection of long noncoding RNAs in a sample, specifically to identify and use of molecular biomarkers or cancer including malignant glioma. Also provided are compositions and methods for treating malignant glioma in a subject, as well as human brain organoid models of malignant glioma and methods of generating and using the same.
    Type: Application
    Filed: March 15, 2021
    Publication date: June 22, 2023
    Inventors: Daniel A. Lim, Martina Malatesta, Siyuan John Liu
  • METHODS OF TREATING PROSTATE CANCER
    Publication number: 20220296574
    Abstract: The present application relates generally to methods for treating prostate cancer with substituted tricyclic derivative is 2-[3-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-5-[(S)-(oxan-4-yl)(phenyl)methyl]-5H-pyrido[3,2-b]indol-7-yl]propan-2-ol as a bromodomain inhibitor, or the pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 7, 2022
    Publication date: September 22, 2022
    Inventors: Martina Malatesta, Ellen Hope Filvaroff
  • METHODS OF TREATING PROSTATE CANCER
    Publication number: 20220265618
    Abstract: The present application relates generally to methods for treating prostate cancer with substituted heterocyclic derivative 4-[2-(cyclopropylmethoxy)-5-methylsulfonylphenyl]-2- methylisoquinolin-1-one as a bromodomain inhibitor, or the pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: February 18, 2022
    Publication date: August 25, 2022
    Applicant: Celgene Quanticel Research, Inc.
    Inventors: Martina Malatesta, Ellen Filvaroff