Abstract: A method of selectively providing access to an inventory of pre-pandemic vaccines is disclosed. The method includes identifying at least two Influenza Viruses of Pandemic Potential (IVPP) to provide available vaccines; determining a stockpile requirement for vaccines against selected IVPPs among the at least two IVPPs; obtaining finished vaccines against each of the selected IVPPs; storing an inventory of finished vaccines against each of the selected IVPPs; providing the finished vaccines against at least one of the selected IVPPs in response to an access request; and periodically obtaining further finished vaccines against one or more of the selected IVPPs and adding the further finished vaccines to the inventory of finished vaccines. Additionally disclosed are methods of selecting the inventory of finished vaccines for an adaptive vaccine stockpile.