Patents by Inventor Martine Bruley-Rosset

Martine Bruley-Rosset has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ig fractions having immunomodulatory activity
    Patent number: 6932969
    Abstract: The invention concerns a method for preparing Ig fractions from human polyvalent intravenous Immunoglobulins (IV Ig) which are in particular likely to be responsible for the immunomodulatory effect observed during the treatment of certain autoimmune diseases. The invention concerns Ig fractions having reactivity to IgM, IgG F(ab?)2 or DNP hapten and no or little reactivity to non-self antigens, that is Ig fractions which have idiotypic interactions among themselves (connected fraction) or which include natural antibodies reacting with the DNP hapten. Said fractions exhibit a polyreactivity to specific autoantigens.
    Type: Grant
    Filed: June 7, 2000
    Date of Patent: August 23, 2005
    Assignee: Laboratoire Francais du Fractionnement et des Biotechnologies
    Inventors: Dominique Bourel, Martine Bruley-Rosset, Frédéric Dhainaut, Jacky Lirochon
  • Antibody stimulating il-ira production
    Publication number: 20050089520
    Abstract: The invention concerns natural antibodies eventually monoclonal capable of inducing a high production of IL-1Ra with monocytes or macrophages and the use of said antibodies for treating inflammatory or autoimmune diseases.
    Type: Application
    Filed: November 8, 2002
    Publication date: April 28, 2005
    Inventors: Dominique Bourel, Martine Bruley-Rosset, Frederic Dhainaut, Jacky Lirochon