Patents by Inventor Martine Gilleron

Martine Gilleron has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8268801
    Abstract: The present invention relates to compounds of the following general formula (I) their process of preparation and their use in the treatment or the prophylaxis of tuberculosis.
    Type: Grant
    Filed: January 11, 2008
    Date of Patent: September 18, 2012
    Assignee: Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Germain Puzo, Jacques Prandi, Martine Gilleron, Gennaro De Libero, Julie Guiard, Lucia Mori, Samantha Paoletti
  • Patent number: 8153610
    Abstract: The present invention relates to compounds of the following general formula: (I) wherein R1 and R2 are fatty acyl groups, a process to extract them from Mycobacterium tuberculosis, and their use in the treatment or the prophylaxis of tuberculosis.
    Type: Grant
    Filed: April 9, 2004
    Date of Patent: April 10, 2012
    Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), University Hospital of Basel, University of Erlangen
    Inventors: Germain Puzo, Martine Gilleron, Steffen Stenger, Gennaro De Libero
  • Publication number: 20100255015
    Abstract: The present invention relates to the therapeutic use of actinomycete glycerol monomycolate derivatives as antigens, their process of extraction, and their use in the treatment or the prophylaxis of tuberculosis.
    Type: Application
    Filed: October 13, 2008
    Publication date: October 7, 2010
    Inventors: Germain Puzo, Emilie Layre, Martine Gilleron, Jacques Prandi, Gennaro De Libero, Steffen Stenger
  • Publication number: 20100166801
    Abstract: The present invention relates to compounds of the following general formula (I) their process of preparation and their use in the treatment or the prophylaxis of tuberculosis.
    Type: Application
    Filed: January 11, 2008
    Publication date: July 1, 2010
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
    Inventors: Germain Puzo, Jacques Prandi, Martine Gilleron, Gennaro De Libero, Julie Guiard, Lucia Mori, Samantha Paoletti
  • Publication number: 20100048492
    Abstract: The present invention relates to a pharmaceutical composition comprising at least one compound of formula (I): or one of its pharmaceutically acceptable salts in which R1, R2 and R3 are independently a hydrogen or an R7—CO— group where R7 is an alkyl, alkene or alkyne group, linear, branched or cyclic, comprising 2 to 24 carbon atoms; R4 is a hydrogen atom or a mannosyl group substituted in position 6 by an R6 residue chosen from the group comprising a hydrogen atom and an R7—CO— group; and R5 is chosen from the group comprising a hydrogen atom, a mono-, di-, tri-, tetra- and penta-mannosyl; and the use of such a composition for manufacturing a medication intended for the prevention or treatment of an illness associated with the over-expression of TNF and/or IL-12 in a subject.
    Type: Application
    Filed: November 20, 2007
    Publication date: February 25, 2010
    Inventors: Valérie Quesniaux Ryffel, Germain Puzo, Jérôme Nigou, Martine Gilleron
  • Publication number: 20080176818
    Abstract: The present invention relates to compounds of the following general formula: (I) wherein R1 and R2 are fatty acyl groups, a process to extract them from Mycobacterium tuberculosis, and their use in the treatment or the prophylaxis of tuberculosis.
    Type: Application
    Filed: April 9, 2004
    Publication date: July 24, 2008
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Germain Puzo, Martine Gilleron, Steffen Stenger, Gennaro De Libero