Patents by Inventor Martine Simonelig

Martine Simonelig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL PFAR-INHIBITING COMPOUNDS
    Publication number: 20220273637
    Abstract: The invention relates to novel compounds which are inhibitors of the ribosome protein chaperone activity (“protein folding activity of the ribosome” or “PFAR”). More particularly, the invention relates to their use as PFAR-inhibitors, to compositions comprising them and to methods for treating proteinopathies.
    Type: Application
    Filed: July 9, 2020
    Publication date: September 1, 2022
    Inventors: MARTINE SIMONELIG, FRÉDÉRIC BIHEL, CÉCILE VOISSET, CAPUCINE TROLLET
  • PROTEASOME INHIBITORS FOR TREATING A DISORDER RELATED TO AN ACCUMULATION OF NON-DEGRADED ABNORMAL PROTEIN OR A CANCER
    Publication number: 20170368134
    Abstract: The invention relates to a proteasome inhibitor for use for treating and/or preventing a disorder related to an accumulation of a non-degraded abnormal protein, particularly a premature ageing disorder. The invention also relates to the use of proteasome inhibitors for attenuating physiological ageing. The invention also relates to the use of proteasome inhibitors in the treatment and/or prevention of age-related disorders and their metabolic consequences. The invention also relates to the dermato logical, dermo cosmetic or cosmetic use of a proteasome inhibitor for preventing and/or attenuating skin ageing. The invention also relates to the use of proteasome inhibitors in the treatment of cancer.
    Type: Application
    Filed: January 14, 2016
    Publication date: December 28, 2017
    Inventors: Nicolas Levy, Pierre Cau, Annachiara De Sandre-Giovannoli, Karim Harhouri, Sophie Perrin, Claire Navarro, Aymeric Chartier, Martine Simonelig