Patents by Inventor Martins Katkevics

Martins Katkevics has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel Process for Preparing Nucleotide P(V) Monomers
    Publication number: 20220194976
    Abstract: The present invention relates to an optimized method for preparing a P(V) monomer of formula (IIIa) or (IIIb) from a nucleoside using DBU as a base at about 0.8 equivalent to nucleoside.
    Type: Application
    Filed: April 14, 2020
    Publication date: June 23, 2022
    Inventors: Dace Katkevica, Martins Katkevics, Erik Funder, Nanna Albaek
  • Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors
    Publication number: 20130035358
    Abstract: There is provided compounds of formula I, wherein E1, E2a, E2b, E2c, E4, D1, D2, D3, L1, Y1, L2 and Y2 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of a respiratory disorder and/or inflammation.
    Type: Application
    Filed: March 14, 2011
    Publication date: February 7, 2013
    Inventors: Peter Nilsson, Benjamin Pelcman, Martins Katkevics, Robert Ronn, Christian Krog-Jensen
  • Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors
    Publication number: 20120035217
    Abstract: There is provided compounds of formula I, wherein Y, ring A, D1, D2a, D2b, D3, L1, Y1, L2 and Y2 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of a respiratory disorder and/or inflammation.
    Type: Application
    Filed: March 12, 2010
    Publication date: February 9, 2012
    Applicant: BIOLIPOX AB
    Inventors: Peter Nilsson, Benjamin Pelcman, Martins Katkevics, Edgars Suna, Ilya Popovs
  • Indoles useful in the treatment of inflammation
    Patent number: 8097623
    Abstract: There is provided compounds of formula (I), wherein X1, Q, T, Y, R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: January 17, 2012
    Assignee: Biolipox AB
    Inventors: Benjamin Pelcman, Kristofer Olofsson, Martins Katkevics, Vita Ozola, Edgars Suna, Ivars Kalvins, Peteris Trapencieris, Dace Katkevica, Wesley Schaal
  • Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors
    Publication number: 20120004244
    Abstract: There is provided compounds of formula I, wherein E1, E2a, E2b, E2c, E4, D1, D2, D3, L1, Y1, L2 and Y2 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of a respiratory disorder and/or inflammation.
    Type: Application
    Filed: March 12, 2010
    Publication date: January 5, 2012
    Applicant: BIOLIPOX AB
    Inventors: Peter Nilsson, Benjamin Pelcman, Martins Katkevics
  • Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors
    Publication number: 20120004228
    Abstract: There is provided compounds of formula I, wherein Y, ring A, Da, Db, D2, D3, L1, Y1, L2, Y2, L3 and Y3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of a respiratory disorder and/or inflammation.
    Type: Application
    Filed: March 12, 2010
    Publication date: January 5, 2012
    Applicant: BIOLIPOX AB
    Inventors: Peter Nilsson, Benjamin Pelcman, Martins Katkevics
  • Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors
    Publication number: 20110319431
    Abstract: There is provided compounds of formula I, wherein Y, ring A, D1, D2a, D2b, D3, L1, Y1, L3 and Y3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of a respiratory disorder and/or inflammation.
    Type: Application
    Filed: March 15, 2010
    Publication date: December 29, 2011
    Applicant: BIOLIPOX AB
    Inventors: Peter Nilsson, Benjamin Pelcman, Martins Katkevics
  • Bis Aromatic Compounds for Use in the Treatment of Inflammation
    Publication number: 20110294853
    Abstract: There is provided compounds of formula (I), wherein ring A, D1, D2a, D2b, D3, Y, Y1, L3 and Y3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of a respiratory disorder and/or inflammation.
    Type: Application
    Filed: September 10, 2009
    Publication date: December 1, 2011
    Inventors: Benjamin Pelcman, Maria Almeida, Martins Katkevics, Peter Nilsson, Wesley Schaal, Kristofer Olofsson
  • BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS
    Publication number: 20110112193
    Abstract: There is provided compounds of formula (I), wherein ring A, D1, D2a, D2b, D3, L1, Y1, L3 and Y3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of a respiratory disorder and/or inflammation.
    Type: Application
    Filed: May 5, 2009
    Publication date: May 12, 2011
    Inventors: Peter Nilsson, Benjamin Pelcman, Martins Katkevics
  • BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS
    Publication number: 20110071197
    Abstract: There is provided compounds of formula I, wherein ring A, D1, D2a, D2b, D3, L1, Y1, L3 and Y3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of a respiratory disorder and/or inflammation.
    Type: Application
    Filed: April 16, 2009
    Publication date: March 24, 2011
    Inventors: Peter Nilsson, Martins Katkevics, Benjamin Pelcman
  • BIS-AROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION
    Publication number: 20100286215
    Abstract: There is provided compounds of formula (I): wherein Y, ring A, D1, D2, D3, L1, Y1, L2, Y2, L3 and Y3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of a respiratory disorder and/or inflammation.
    Type: Application
    Filed: September 3, 2008
    Publication date: November 11, 2010
    Inventors: Benjamin Pelcman, Peter Nilsson, Martins Katkevics
  • Indoles Useful in the Treatment of Inflammation
    Publication number: 20100197687
    Abstract: There is provided compounds of formula I, wherein T, Y, X1, R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.
    Type: Application
    Filed: December 22, 2005
    Publication date: August 5, 2010
    Inventors: Benjamin Pelcman, Kristofer Olofsson, Martins Katkevics, Vita Ozola, Edgars Suna, Ivars Kalvins, Peteris Trapencieris, Dace Katkevica, Wesley Schaal
  • Indoles useful in the treatment of inflammation
    Patent number: 7705023
    Abstract: There is provided a compound of formula: (I), wherein X, R1, R2, R3, R4, R5 and R6 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of microsomal prostaglandin E synthase-1 is desired and/or required, and particularly in the treatment of inflammation.
    Type: Grant
    Filed: June 17, 2005
    Date of Patent: April 27, 2010
    Assignee: Biolipox AB
    Inventors: Kristofer Olofsson, Benjamin Pelcman, Ivars Kalvins, Edgars Suna, Vita Ozola, Martins Katkevics
  • Benzoxazoles Useful in the Treatment of Inflammation
    Publication number: 20090258917
    Abstract: There is provided the use of a compound of formula I, wherein Y, W1 to W4, Z1 to Z4 and R have meanings given in the description, and pharmaceutically-acceptable salts thereof, for the manufacture of a medicament for the treatment of a disease in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.
    Type: Application
    Filed: October 12, 2006
    Publication date: October 15, 2009
    Inventors: Benjamin Pelcman, Kristofer Olofsson, Wesley Schaal, Ivars Kalvins, Martins Katkevics, Vita Ozola, Edgars Suna
  • Indoles Useful in the Treatment of Inflammation
    Publication number: 20090076004
    Abstract: There is provided compounds of formula (I), wherein X1, Q, T, Y, R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.
    Type: Application
    Filed: December 22, 2005
    Publication date: March 19, 2009
    Inventors: Benjamin Pelcman, Kristofer Olofsson, Martins Katkevics, Vita Ozola, Edgars Suna, Ivars Kalvins, Peteris Trapencieris, Dace Katkevica, Wesley Schaal
  • Pyrrolopyridines Useful in the Treatment of Inflammation
    Publication number: 20090048285
    Abstract: There is provided compounds of formula (I), wherein X1, R1, R2, Y1, Y2, Y3 and Y4 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.
    Type: Application
    Filed: January 19, 2006
    Publication date: February 19, 2009
    Inventors: Benjamin Pelcman, Kristofer Olofsson, Pavels Arsenjans, Ivars Kalvins, Edgars Suna, Martins Katkevics, Marina Madre, Vita Ozola
  • Indoles Useful in the Treatment of Inflammation
    Publication number: 20090042949
    Abstract: There is provided compounds of formula I, wherein X1, T, Y, R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.
    Type: Application
    Filed: December 22, 2005
    Publication date: February 12, 2009
    Inventors: Benjamin Pelcman, Kristofer Olofsson, Martins Katkevics, Vita Ozola, Edgars Suna, Ivars Kalvins, Wesley Schaal
  • Indoles Useful in the Treatment of Inflammation
    Publication number: 20080249091
    Abstract: There is provided compounds of formula I, wherein X1, R1, R2, R3, R4, R5 and R6 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.
    Type: Application
    Filed: December 22, 2005
    Publication date: October 9, 2008
    Inventors: Benjamin Pelcman, Kristofer Olofsson, Martins Katkevics, Vita Ozola, Edgars Suna, Ivars Kalvins, Peteris Trapencieris
  • Indoles Useful in the Treatment of Inflammation
    Publication number: 20080188473
    Abstract: There is provided a compound of formula: (I) wherein X, R1, R2, R3, R4, R5, R6, R7 and R8 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of microsomal prostaglandin E synthase-1 is desired and/or required, and particularly in the treatment of inflammation.
    Type: Application
    Filed: June 17, 2005
    Publication date: August 7, 2008
    Inventors: Kristofer Olofsson, Benjamin Pelcman, Wesley Schaal, Ivars Kalvins, Edgars Suna, Vita Ozola, Martins Katkevics
  • Indoles Useful in the Treatment of Inflammation
    Publication number: 20080146616
    Abstract: There is provided a compound of formula (I), wherein X, R1, R2, R3, R4, R5 and R6 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of microsomal prostaglandin E synthase-1 is desired and/or required, and particularly in the treatment of inflammation.
    Type: Application
    Filed: June 17, 2005
    Publication date: June 19, 2008
    Inventors: Kristofer Olofsson, Benjamin Pelcman, Wesley Schaal, Ivars Kalvins, Edgars Suna, Vita Ozola, Martins Katkevics