Patents by Inventor Martti Lauri Antero Marvola

Martti Lauri Antero Marvola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peroral composition for controlled release in the lower gastrointestinal tract
    Patent number: 5962024
    Abstract: The invention relates to a peroral composition providing controlled release of a drug, the composition comprising a) a core comprising the drug and a drug release controlling agent and b) an enteric coating comprising the drug release controlling agent, wherein the drug release controlling agent consists substantially of a pH-sensitive enteric polymer. Preferably the pH-sensitive enteric polymer has a pH dissolving point of at least 6.5. The composition is preferably in the form of granules. Preferably, the composition is in the form of enteric matrix granules coated with an enteric coating. The composition releases the drug gradually in the lower gastrointestinal tract. The composition is especially suitable for the administration of 3-(3-cyanophenyl)methylene-2,4-pentanedione into the colon.
    Type: Grant
    Filed: December 2, 1997
    Date of Patent: October 5, 1999
    Assignee: Orion-Yhtyma OY
    Inventors: Martti Lauri Antero Marvola, Esko Veikko Marttila, Reija Tuulikki Yrjola, Esa Petteri Lahdenpaa
  • Controlled release pharmaceutical
    Patent number: 5849330
    Abstract: The invention relates to long-acting pharmaceutical compositions from which the release of the active compound increases exponentially, and to a process for their preparation. The composition, preferably a tablet, comprises a rapid releasing core and a slow-releasing coat surrounding that core.
    Type: Grant
    Filed: March 6, 1996
    Date of Patent: December 15, 1998
    Assignee: Orion-yhtyma Oy
    Inventors: Martti Lauri Antero Marvola, Taina Sirkia