Patents by Inventor Martyna Simutyte

Martyna Simutyte has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thermophilic DNA polymerase mutants
    Patent number: 11560553
    Abstract: This disclosure relates to thermophilic family B DNA polymerases comprising a neutral amino acid residue at a certain position near the C-terminus of the catalytic domain, which corresponds to a position occupied by a basic amino acid residue in wild-type Pfu polymerase. Related uses, methods, and compositions are also provided. In some embodiments, the polymerases comprise a 3?-5? exonuclease domain and/or a sequence non-specific dsDNA binding domain.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: January 24, 2023
    Assignee: THERMO FISHER SCIENTIFIC BALTICS UAB
    Inventors: Remigijus Skirgaila, Renata Rimseliene, Rasa Sukackaite, Martyna Simutyte, Skaiste Valinskyte, Karolis Matjosaitis, Mindaugas Ukanis
  • THERMOPHILIC DNA POLYMERASE MUTANTS
    Publication number: 20200325460
    Abstract: This disclosure relates to thermophilic family B DNA polymerases comprising a neutral amino acid residue at a certain position near the C-terminus of the catalytic domain, which corresponds to a position occupied by a basic amino acid residue in wild-type Pfu polymerase. Related uses, methods, and compositions are also provided. In some embodiments, the polymerases comprise a 3?-5? exonuclease domain and/or a sequence non-specific dsDNA binding domain.
    Type: Application
    Filed: April 8, 2020
    Publication date: October 15, 2020
    Inventors: Remigijus SKIRGAILA, Renata RIMSELIENE, Rasa SUKACKAITE, Martyna SIMUTYTE, Skaiste VALINSKYTE, Karolis MATJOSAITIS, Mindaugas UKANIS
  • Thermophilic DNA polymerase mutants
    Patent number: 10626383
    Abstract: This disclosure relates to thermophilic family B DNA polymerases comprising a neutral amino acid residue at a certain position near the C-terminus of the catalytic domain, which corresponds to a position occupied by a basic amino acid residue in wild-type Pfu polymerase. Related uses, methods, and compositions are also provided. In some embodiments, the polymerases comprise a 3?-5? exonuclease domain and/or a sequence non-specific dsDNA binding domain.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: April 21, 2020
    Assignee: THERMO FISHER SCIENTIFIC BALTICS UAB
    Inventors: Remigijus Skirgaila, Renata Rimseliene, Rasa Sukackaite, Martyna Simutyte, Skaiste Valinskyte, Karolis Matjosaitis, Mindaugas Ukanis
  • THERMOPHILIC DNA POLYMERASE MUTANTS
    Publication number: 20170204384
    Abstract: This disclosure relates to thermophilic family B DNA polymerases comprising a neutral amino acid residue at a certain position near the C-terminus of the catalytic domain, which corresponds to a position occupied by a basic amino acid residue in wild-type Pfu polymerase. Related uses, methods, and compositions are also provided. In some embodiments, the polymerases comprise a 3?-5? exonuclease domain and/or a sequence non-specific dsDNA binding domain.
    Type: Application
    Filed: January 13, 2017
    Publication date: July 20, 2017
    Applicant: Thermo Fisher Scientific Baltics UAB
    Inventors: Remigijus Skirgaila, Renata Rimseliene, Rasa Sukackaite, Martyna Simutyte, Skaiste Valinskyte, Karolis Matjosaitis, Mindaugas Ukanis