Patents by Inventor MARUTA BUNKA

MARUTA BUNKA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODUCTION OF 43SC RADIONUCLIDE AND ITS USE IN POSITRON EMISSION TOMOGRAPHY
    Publication number: 20190307909
    Abstract: The radionuclide 43Sc is produced at commercially significant yields and at specific activities and radionuclidic purities which are suitable for use in radiodiagnostic agents including imaging agents. In a method, a solid target having an isotopically enriched target layer prepared on an inert substrate is positioned in a specially configured target holder and irradiated with a charged-particle beam of protons or deuterons. The beam is generated using an accelerator such as a biomedical cyclotron at energies ranging from 3 to about 22. MeV. The method includes the use of three different nuclear reactions: a) irradiation of enriched 43Ca targets with protons to generate the radionuclide 43Scin the nuclear reaction 43Ca (p,n)43Sc, b) irradiation of enriched 42Ca targets with deuterons to generate the radionuclide 43Sc in the nuclear reaction 42Ca(d,n)43Sc, and c) irradiation of enriched 46Ti targets with protons to generate the radionuclide 43Sc in the nuclear reaction 46Ti (p,a) 43Sc.
    Type: Application
    Filed: May 21, 2019
    Publication date: October 10, 2019
    Inventors: ANDREAS TUERLER, NICHOLAS VAN DER MEULEN, MARUTA BUNKA
  • Production of 43SC radionuclide and radiopharmaceuticals thereof for use in positron emission tomography
    Patent number: 10357578
    Abstract: The radionuclide 43Sc is produced at commercially significant yields and at specific activities and radionuclidic purities which are suitable for use in radiodiagnostic agents including imaging agents. In a method, a solid target having an isotopically enriched target layer prepared on an inert substrate is positioned in a specially configured target holder and irradiated with a charged-particle beam of protons or deuterons. The beam is generated using an accelerator such as a biomedical cyclotron at energies ranging from 3 to about 22 MeV. The method includes the use of three different nuclear reactions: a) irradiation of enriched 43Ca targets with protons to generate the radionuclide 43Scin the nuclear reaction 43Ca (p,n)43Sc, b) irradiation of enriched 42Ca targets with deuterons to generate the radionuclide 43Sc in the nuclear reaction 42Ca(d,n)43Sc, and c) irradiation of enriched 46Ti targets with protons to generate the radionuclide 43Sc in the nuclear reaction 46Ti (p,a)43Sc.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: July 23, 2019
    Assignee: Paul Scherrer Institut
    Inventors: Andreas Tuerler, Nicholas Van Der Meulen, Maruta Bunka
  • PRODUCTION OF 43SC RADIONUCLIDE AND RADIOPHARMACEUTICALS THEREOF FOR USE IN POSITRON EMISSION TOMOGRAPHY
    Publication number: 20170087260
    Abstract: The radionuclide 43Sc is produced at commercially significant yields and at specific activities and radionuclidic purities which are suitable for use in radiodiagnostic agents including imaging agents. In a method, a solid target having an isotopically enriched target layer prepared on an inert substrate is positioned in a specially configured target holder and irradiated with a charged-particle beam of protons or deuterons. The beam is generated using an accelerator such as a biomedical cyclotron at energies ranging from 3 to about 22 MeV. The method includes the use of three different nuclear reactions: a) irradiation of enriched 43Ca targets with protons to generate the radionuclide 43Scin the nuclear reaction 43Ca (p,n)43Sc, b) irradiation of enriched 42Ca targets with deuterons to generate the radionuclide 43Sc in the nuclear reaction 42Ca(d,n)43Sc, and c) irradiation of enriched 46Ti targets with protons to generate the radionuclide 43Sc in the nuclear reaction 46Ti (p,a)43Sc.
    Type: Application
    Filed: May 7, 2015
    Publication date: March 30, 2017
    Inventors: ANDREAS TUERLER, NICHOLAS VAN DER MEULEN, MARUTA BUNKA