Patents by Inventor Maruyama Toshiaki

Maruyama Toshiaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
    Publication number: 20090017046
    Abstract: Cancer treatments use a therapy that: 1) interferes with the interaction between CD200 and its receptor to block immune suppression thereby promoting eradication of the cancer cells; and 2) directly kills the cancer cells either by complement-mediated or antibody-dependent cellular cytotoxicity or by targeting cells using a fusion molecule that includes a CD200-targeting portion. The therapy includes the administration of novel antibodies, functional fragments thereof or fusion molecules containing portions thereof.
    Type: Application
    Filed: July 30, 2008
    Publication date: January 15, 2009
    Applicant: Alexion Pharmaceuticals, Inc.
    Inventors: Katherine S. Bowdish, John McWhirter, Anke Kretz-Rommel, Maruyama Toshiaki
  • Nested oligonucleotides containing a hairpin for nucleic acid amplification
    Patent number: 6919189
    Abstract: Templates that are engineered to contain a predetermined sequence and a hairpin structure are provided by a nested oligonucleotide extension reaction. The engineered template allows Single Primer Amplification (SPA) to amplify a target sequence within the engineered template. In particularly useful embodiments, the target sequences from the engineered templates are cloned into expression vehicles to provide a library of polypeptides or proteins, such as, for example, an antibody library.
    Type: Grant
    Filed: December 10, 2001
    Date of Patent: July 19, 2005
    Assignee: Alexion Pharmaceuticals, Inc.
    Inventors: Katherine S. Bowdish, Shana Frederickson, John McWhirter, Maruyama Toshiaki
  • NESTED OLIGONUCLEOTIDES CONTAINING A HAIRPIN FOR NUCLEIC ACID AMPLIFICATION
    Publication number: 20050079489
    Abstract: Templates that are engineered to contain a predetermined sequence and a hairpin structure are provided by a nested oligonucleotide extension reaction. The engineered template allows Single Primer Amplification (SPA) to amplify a target sequence within the engineered template. In particularly useful embodiments, the target sequences from the engineered templates are cloned into expression vehicles to provide a library of polypeptides or proteins, such as, for example, an antibody library.
    Type: Application
    Filed: December 10, 2001
    Publication date: April 14, 2005
    Inventors: Katherine Bowdish, Shana Frederickson, John McWhirter, Maruyama Toshiaki
  • Nested oligonucleotides containing a hairpin for nucleic acid amplification
    Publication number: 20040101886
    Abstract: Templates that are engineered to contain a predetermined sequence and a hairpin structure are provided by a nested oligonucleotide extension reaction. The engineered template allows Single Primer Amplification (SPA) to amplify a target sequence within the engineered template. In particularly useful embodiments, the target sequences from the engineered templates are cloned into expression vehicles to provide a library of polypeptides or proteins, such as, for example, an antibody library.
    Type: Application
    Filed: July 28, 2003
    Publication date: May 27, 2004
    Inventors: Katherine S. Bowdish, Shana Frederickson, John McWhirter, Maruyama Toshiaki