Abstract: The invention relates to a method of cell culture where the cells are modified to reduce the level of synthesis of growth and/or productivity inhibitors by the cell. The invention also relates to a method of cell culture for improving cell growth and productivity, in particular in fed-batch culture of mammalian cells at high cell density. The invention further relates to a method of producing cells with improved cell growth and/or productivity in cell culture and to cells obtained or obtainable by such methods.

Abstract: A serving board is disclosed for supporting an edible product. The serving board comprises a first board defining a lower surface, an upper surface and a first edge. A second board defines a lower surface, an upper surface and a second edge. A spacing layer extends between the lower surface of the first board and the upper surface of the second board. The spacing layer distances the first board from the second board for defining a chamber. An integrated circuit is positioned in the chamber. An electrical power source is positioned in the chamber and electrically coupled to the integrated circuit. An output device electrically is coupled to the integrated circuit for producing a sensatory output. The first board, the second board and the spacing layer are constructed from a biodegradable material.

Abstract: Analyzing a design of a hardware device includes obtaining a computer-aided design assembly depicting the design and automatically creating a bill of materials based on the computer-aided design assembly, wherein the bill of materials lists in a hierarchical manner a plurality of components making up the design. In another embodiment, analyzing a design of a hardware device includes automatically creating a bill of materials based on a computer-aided design assembly depicting the design and automatically updating the bill of materials to include business and technical information retrieved from a database, wherein the automatically updating results in an updated bill of materials.

Abstract: A system for analyzing a design of a hardware device includes a database that stores business and technical information related to a plurality of components included in the design and a hardware design assistant coupled to the database and including a processor for automatically creating a bill of materials based on a computer-aided design assembly of the design and on the business and technical information. Another embodiment of a system for analyzing a design of a hardware device includes a processor and a computer readable storage medium that stores instructions which, when executed, cause the processor to perform operations including obtaining a computer-aided design assembly depicting the design and automatically creating a bill of materials based on the computer-aided design assembly, wherein the bill of materials lists in a hierarchical manner a plurality of components making up the design.

Abstract: A pair of thickness-shear mode resonators, one smooth and one with a textured surface, allows fluid density and viscosity to be independently resolved. A textured surface, either randomly rough or regularly patterned, leads to trapping of liquid at the device surface. The synchronous motion of this trapped liquid with the oscillating device surface allows the device to weigh the liquid; this leads to an additional response that depends on liquid density. This additional response enables a pair of devices, one smooth and one textured, to independently resolve liquid density and viscosity; the difference in responses determines the density while the smooth device determines the density-viscosity product, and thus, the pair determines both density and viscosity.

Abstract: A pair of thickness-shear mode resonators, one smooth and one with a textured surface, allows fluid density and viscosity to be independently resolved. A textured surface, either randomly rough or regularly patterned, leads to trapping of liquid at the device surface. The synchronous motion of this trapped liquid with the oscillating device surface allows the device to weigh the liquid; this leads to an additional response that depends on liquid density. This additional response enables a pair of devices, one smooth and one textured, to independently resolve liquid density and viscosity; the difference in responses determines the density while the smooth device determines the density-viscosity product, and thus, the pair determines both density and viscosity.