Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: This application relates to ink compositions, in particular ink compositions for use in continuous inkjet printing. The ink compositions are suitable for producing printed images for example with reduced printer error and good adhesion to low surface energy substrates, in particular, low energy substrates such as polypropylene, LDPE and HDPE. The ink composition contains a liquid carrier and carbon black. The ink composition has a surface resistance of at least 2 M?/sq after washing the printed deposit with the liquid carrier and an adhesion of 50% or more after applying an adhesive tape to the printed deposit and removing the adhesive tape.

Abstract: The present invention relates to compositions comprising novel (per)fluoropolyether polymers, endowed with antimicrobial properties, to methods for the manufacture thereof and to their use to provide compositions having antimicrobial properties.

Abstract: The present invention relates to compositions comprising novel (per)fluoropolyether polymers, endowed with antimicrobial properties, to methods for the manufacture thereof and to their use to provide compositions having antimicrobial properties.

Abstract: This application relates to an ink composition, in particular an ink composition for use in continuous inkjet printing. The ink composition for use in continuous inkjet printing, contains a siloxane surfactant and a metal conductivity salt. The ink composition is suitable for producing printed images with good adhesion to low surface energy substrates, in particular, low energy substrates such as polypropylene, LDPE and HDPE. The ink composition has a liquid carrier, a colourant, a siloxane surfactant and a metal conductivity salt. The siloxane surfactant is present in an amount greater than 0.1% by weight of the ink composition.

Abstract: An oligomeric resin adduct, compositions comprising the oligomeric resinadduct, and process for making oligomeric resin adduct, wherein the the process includes charging into a reactor a mixture including a vinylic monomer that includes a styrenic monomer, a (meth)acrylic monomer, or a mixture thereof; a polymerization initiator; and optionally a reaction solvent; maintaining the reactor at a temperature sufficient to produce an oligomeric resin from the vinylic monomer; maintaining the vinylic monomer, the polymerization initiator, and optionally the reaction solvent at a sufficient amount to produce the oligomeric resin, wherein the oligomeric resin contains at least one terminal olefinic unsaturation; and reacting the oligomeric resin with a compound of Formula I, Formula II, or a mixture thereof as defined herein.

Abstract: Provided is an inkjet composition for printing an indelible colorant onto a substrate. Also provided is a method of printing using the inkjet composition, and a printed substrate obtainable and obtained from the method of printing. The inkjet composition has an indelible colorant, one or more solvents, and a binder. The migration distance of the indelible colorant in the substrate is less than 0.85 mm after 7 days at 25° C. The composition may be used to provide indelible markings in the surface of the substrate, and these markings do not significantly disperse over time.

Abstract: This application relates to ink compositions, in particular ink compositions for use in continuous inkjet printing. The ink compositions are suitable for producing printed images for example with reduced printer error and good adhesion to low surface energy substrates, in particular, low energy substrates such as polypropylene, LDPE and HDPE. The ink composition contains a liquid carrier and carbon black. The ink composition has a surface resistance of at least 2M?/sq after washing the printed deposit with the liquid carrier and an adhesion of 50 % or more after applying an adhesive tape to the printed deposit and removing the adhesive tape.

Abstract: This application relates to an ink composition, in particular an ink composition for use in continuous inkjet printing. The ink composition for use in continuous inkjet printing, contains a siloxane surfactant and a metal conductivity salt. The ink composition is suitable for producing printed images with good adhesion to low surface energy substrates, in particular, low energy substrates such as polypropylene, LDPE and HDPE. The ink composition has a liquid carrier, a colourant, a siloxane surfactant and a metal conductivity salt. The siloxane surfactant is present in an amount greater than 0.1% by weight of the ink composition.

Abstract: Disclosed herein is a latex paint containing i) a multistage carboxylated polymer latex binder, ii) a titanium dioxide pigment, and iii) a polymeric dispersant PD having a number average molecular weight, as determined by GPC, of at most 5500 Dalton. Also disclosed are methods for preparing the latex paint, and coatings containing the latex paint.

Abstract: The present invention relates to a composition, comprising a binder resin, a block copolymer which comprises at least a block A and a block B, wherein the block A comprises monomer units derived from a compound selected from (meth)acrylic acid, a (meth)acrylic acid ester, a (meth)acrylamide, a vinyl aromatic compound, or any mixture thereof, the block B comprises monomer units derived from a compound selected from a fluorinated (meth)acrylic ester having the following formula (I): H2C?C(R1)(C(O)ORF-1)??(I) wherein R1 is H or methyl; and RF-1 is an organic residue containing a perfluorinated C4-6 alkyl group, a fluorinated alpha-olefin having the following formula (II): H2C?CH(RF-2)??(II) wherein RF-2 is an organic residue containing a perfluorinated C4-6 alkyl group, i.e., —(CF2)3-5—CF3 or any mixture thereof.

Abstract: The present invention relates to a composition, comprising a binder resin, a block copolymer which comprises at least a block A and a block B, wherein the block A comprises monomer units derived from a compound selected from (meth)acrylic acid, a (meth)acrylic acid ester, a (meth)acrylamide, a vinyl aromatic compound, or any mixture thereof, the block B comprises monomer units derived from a compound selected from a fluorinated (meth)acrylic ester having the following formula (I): H2C?C(R1)(C(0)ORF-1), wherein R1 is H or methyl; and RF-1 is an organic residue containing a perfluorinated C4-6 alkyl group, a fluorinated alpha-olefin having the following formula (II): H2C?CH(RF-2) (II) wherein RF-2 is an organic residue containing a perfluorinated C4-6 alkyl group, i.e. —(CF2)3-5—CF3 or any mixture thereof.

Abstract: The present invention relates to a composition, comprising a binder resin, a block copolymer which comprises at least a block A and a block B, wherein the block A comprises monomer units derived from a compound selected from (meth)acrylic acid, a (meth)acrylic acid ester, a (meth)acrylamide, a vinyl aromatic compound, or any mixture thereof, the block B comprises monomer units derived from a compound selected from a fluorinated (meth)acrylic ester having the following formula (I): H2C?C(R1)(C(O)ORF?1)??(I) wherein R1 is H or methyl; and RF?1 is an organic residue containing a perfluorinated C4-6 alkyl group, a fluorinated alpha-olefin having the following formula (II): H2C?CH(RF?2)??(II) wherein RF?2 is an organic residue containing a perfluorinated C4-6 alkyl group, i.e., —(CF2)3-5—CF3 or any mixture thereof.

Abstract: The present invention relates to a composition, comprising a binder resin, a block copolymer which comprises at least a block A and a block B, wherein the block A comprises monomer units derived from a compound selected from (meth)acrylic acid, a (meth)acrylic acid ester, a (meth)acrylamide, a vinyl aromatic compound, or any mixture thereof, the block B comprises monomer units derived from a compound selected from a fluorinated (meth)acrylic ester having the following formula (I): H2C?C(R1)(C(0)ORF-1), wherein R1 is H or methyl; and RF-1 is an organic residue containing a perfluorinated C4-6alkyl group, a fluorinated alpha-olefin having the following formula (II): H2C?CH(RF-2) (II) wherein RF-2 is an organic residue containing a perfluorinated C4-6 alkyl group, i.e. —(CF2)3-5—CF3 or any mixture thereof.

Abstract: A spectroscopic method is disclosed for detecting and measuring contaminants in fluids such as water or oil, where the hydrophilicity of the contaminant is substantially different from that of the contaminated fluid. Good calibrations can be obtained at very low concentrations using infrared spectroscopy with ATR crystals that have not been additionally coated or otherwise modified.

Abstract: A spectroscopic method is disclosed for detecting and measuring contaminants in fluids such as water or oil, where the hydrophilicity of the contaminant is substantially different from that of the contaminated fluid. Good calibrations can be obtained at very low concentrations using infrared spectroscopy with ATR crystals that have not been additionally coated or otherwise modified.

Abstract: A locking mechanism to secure both a zipper used to seal an opening of a bag in a closed configuration and a cable integrated into the bag to secure the bag to an object is disclosed. The locking mechanism may include a pin housing to receive a pin secured to an end of the cable, a thumb tab to secure a zipper head thereto, and a lock to lock the thumb tab and the pin housing in a secure configuration. The locking mechanism may provide a single control to conveniently release both the zipper and the cable. The lock may disengage the thumb tab and the thumb tab may disengage the pin housing. The lock may disengage the thumb tab or the pin housing based on the way the lock is unlocked. The bag may be made of a material that is resistant to cutting and gouging.

Abstract: A bag comprising a lockable pouch and a lockable handle is disclosed. The bag comprises a locking mechanism that secures the contents of the bag by securing a sliding fastener in place. In one embodiment, the handle and sliding fastener are both secured via a common key-operated mechanism. A handle that is removal at one end allows the handle to be placed around a stationary object as to secure the bag to that object while unattended. A single control is provided conveniently to release both the sliding fastener and the handle. The handle is comprised of a flexible yet strong material, such as a metal cable.

Abstract: A bag comprising a lockable pouch and a lockable handle is disclosed. The bag comprises a locking mechanism that secures the contents of the bag by securing a sliding fastener in place. In one embodiment, the handle and sliding fastener are both secured via a common key-operated mechanism. A handle that is removal at one end allows the handle to be placed around a stationary object as to secure the bag to that object while unattended. A single control is provided conveniently to release both the sliding fastener and the handle. The handle is comprised of a flexible yet strong material, such as a metal cable.

Abstract: A bag comprising a lockable pouch and a lockable handle is disclosed. The bag comprises a locking mechanism that secures the contents of the bag by securing a sliding fastener in place. In one embodiment, the handle and sliding fastener are both secured via a common key-operated mechanism. A handle that is removal at one end allows the handle to be placed around a stationary object as to secure the bag to that object while unattended. A single control is provided conveniently to release both the sliding fastener and the handle. The handle is comprised of a flexible yet strong material, such as a metal cable.