Patents by Inventor Mary Ann Lila

Mary Ann Lila has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for attenuating allergenicity in protein products
    Patent number: 11452706
    Abstract: The invention relates to a low sugar or sugar free concentrated polyphenolic extract comprising at least about 30% polyphenols (w/w) and a protein-polyphenol aggregate matrix comprising at least about 15% polyphenols (w/w). The invention further relates to methods of producing a low sugar or sugar free concentrated polyphenolic extract comprising (a) extracting a low sugar or sugar free plant tissue with an aqueous solvent to produce an extract having an aqueous portion and a solids portion; (b) filtering the extract to separate the aqueous portion from the solids portion; and (c) reducing the volume of the separated aqueous portion, and methods of producing a protein-polyphenol aggregate matrix comprising about 1% to about 40% polyphenols (w/w) using the low sugar or sugar free concentrated polyphenolic extract of the invention.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: September 27, 2022
    Assignee: NORTH CAROLINA STATE UNIVERSITY
    Inventors: Mary Ann Lila, Mary H. Grace
  • Polyphenol-protein compositions
    Patent number: 11172699
    Abstract: The invention relates to a composition having polyphenols, protein and a final moisture content of at least about 0.1% by weight and methods of making the same. In some aspects, a composition of the invention includes about 5% to about 40% polyphenols by weight and about 60% to about 90% protein by weight. In other aspects, methods of producing compositions including polyphenols and protein are provided.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: November 16, 2021
    Assignees: NORTH CAROLINA STATE UNIVERSITY, SINNOVATEK, INC.
    Inventors: Mary Ann Lila, Josip Simunovic, Michael Druga, Amanda Vargochik
  • POLYPHENOL-PROTEIN COMPOSITIONS AND METHODS OF MAKING
    Publication number: 20200029611
    Abstract: The invention relates to a composition comprising polyphenols, protein and a final moisture content of at least about 0.1% by weight and methods of making the same. In some aspects, a composition of the invention comprises about 5% to about 40% polyphenols by weight and about 60% to about 90% protein by weight. In other aspects, methods of producing compositions comprising polyphenols and protein are provided.
    Type: Application
    Filed: December 21, 2017
    Publication date: January 30, 2020
    Inventors: Mary Ann Lila, Josip Simunovic, Michael Druga, Amanda Vargochik
  • METHODS AND COMPOSITIONS FOR ATTENUATING ALLERGENICITY IN PROTEIN PRODUCTS
    Publication number: 20170333386
    Abstract: The invention relates to a low sugar or sugar free concentrated polyphenolic extract comprising at least about 30% polyphenols (w/w) and a protein-polyphenol aggregate matrix comprising at least about 15% polyphenols (w/w). The invention further relates to methods of producing a low sugar or sugar free concentrated polyphenolic extract comprising (a) extracting a low sugar or sugar free plant tissue with an aqueous solvent to produce an extract having an aqueous portion and a solids portion; (b) filtering the extract to separate the aqueous portion from the solids portion; and (c) reducing the volume of the separated aqueous portion, and methods of producing a protein-polyphenol aggregate matrix comprising about 1% to about 40% polyphenols (w/w) using the low sugar or sugar free concentrated polyphenolic extract of the invention.
    Type: Application
    Filed: November 5, 2015
    Publication date: November 23, 2017
    Inventors: Mary Ann Lila, Mary H. Grace
  • HYPOALLERGENIC FOOD-GRADE PROTEIN MATRICES AND USES THEREOF
    Publication number: 20150173406
    Abstract: This invention relates generally to the discovery of improved food-grade protein matrices with reduced allergeiiicity and uses thereof including immunotherapy.
    Type: Application
    Filed: July 9, 2013
    Publication date: June 25, 2015
    Applicants: North Carolina State University, The University of North Carolina at Chapel Hill, The United States of America, as represented by the Secretary of Agriculture
    Inventors: Mary Ann Lila, Mary H. Grace, Jack P. Davis, Wesley Burks, Michael D. Kulis
  • Methods for isolation of proanthocyanidins from flavonoid-producing cell culture
    Publication number: 20030100082
    Abstract: A method for isolation of proanthocyanidins from flavonoid-producing cell cultures is disclosed. More specifically, the invention relates to the isolation of catechin, epicatechin, proanthocyanidin B-2, and other proanthocyanidins from Vaccinium pahalae Skottsberg cultures. The invention also provides a method for modifying the content of proanthocyanidins in a flavonoid-producing culture. Further, the invention relates to a method of performing metabolic studies with proanthocyanidins.
    Type: Application
    Filed: October 25, 2002
    Publication date: May 29, 2003
    Inventors: Mary Ann Lila, David S. Seigler