Abstract: An in situ reconstitutable biological ampoule package is provided which includes an open-ended container having non-frangible, deformable wall structure for receiving a quantity of lyophylized bacteria. An ampoule within the container stores a quantity of a liquid medium for reconstituting the bacterial product. Application of pressure to the ampoule by squeezing of the container effects deformation of the side wall of the ampoule thereby releasing the liquid for reconstitution of the biological product. The ampoule may be either of glass which breaks when subjected to pressure, or of synthetic resin material which collapses when squeezed, thereby causing the stored liquid to be ejected from the ampoule through an aperture in the side wall thereof. A dropper cap closing the open end of the container allows the user to apply the reconstituted bacterial product in a drop-wise fashion to a target medium.