Patents by Inventor Mary B. Rucker

Mary B. Rucker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment for pompe disease
    Publication number: 20030223966
    Abstract: Serotype 1 recombinant adeno-associated virus (rAAV) vectors were used to deliver functional acid alpha-glucosidase genes in vitro and in vivo to muscle cells deficient in acid alpha-glucosidase. The vector-treated cells overexpressed acid alpha-glucosidase. Vector-treated animals displayed restored enzymatic activity and muscle function. Serotype 1 rAAV vectors induced significantly greater acid alpha-glucosidase expression compared to serotype 2 rAAV vectors.
    Type: Application
    Filed: April 30, 2003
    Publication date: December 4, 2003
    Inventors: Thomas J. Fraites, Mary B. Rucker, Barry J. Byrne