Patents by Inventor Mary Bossard

Mary Bossard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymer-factor VIII moiety conjugates
    Publication number: 20080058504
    Abstract: Conjugates of a Factor VIII moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided are compositions comprising the conjugates, methods of making the conjugates, and methods of administering compositions comprising the conjugates to a patient.
    Type: Application
    Filed: February 5, 2007
    Publication date: March 6, 2008
    Inventors: Mary Bossard, Michael Bentley, Ping Zhang
  • Conjugates of a G-CSF moiety and a polymer
    Publication number: 20070092482
    Abstract: Conjugates of a G-CSF moiety and one or more nonpeptidic water-soluble polymers are provided. Typically, the nonpeptidic water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided, among other things, are compositions comprising conjugates, methods of making conjugates, and methods of administering compositions comprising conjugates to a patient.
    Type: Application
    Filed: August 4, 2006
    Publication date: April 26, 2007
    Inventors: Mary Bossard, Ping Zhang
  • Modified protease inhibitors
    Publication number: 20070020252
    Abstract: DX-890 inhibits elastase. DX-890 can be attached a single polyethylene glycol moiety. The polyethylene glycol is at least 18 kDa in molecular weight and is attached to the polypeptide by a single covalent bond to the N-terminus of the polypeptide.
    Type: Application
    Filed: August 30, 2004
    Publication date: January 25, 2007
    Inventors: Robert Ladner, Aaron Sato, Arthur Ley, Michelle Amaral, Mary Bossard, Michael Roberts, Yan Zhang
  • Polymer-based compositions and conjugates of antimicrobial agents
    Publication number: 20060239960
    Abstract: Provided herein are water-soluble polymer conjugates and polymer-based compositions of antimicrobial agents. Also provided are methods for synthesizing and administering such conjugates and compositions.
    Type: Application
    Filed: April 11, 2006
    Publication date: October 26, 2006
    Applicant: Nektar Therapeutics AL, Corporation
    Inventors: Mary Bossard, Stacy Mitchell
  • Conjugates of an hGH moiety and a polymer
    Publication number: 20060233740
    Abstract: Conjugates of an hGH moiety and one or more non-peptidic water-soluble polymers are provided. Typically, the non-peptidic water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided are compositions comprising such conjugates, methods of making the conjugates, and methods of administering compositions comprising such conjugates to a mammalian subject.
    Type: Application
    Filed: March 23, 2006
    Publication date: October 19, 2006
    Inventors: Mary Bossard, Ping Zhang
  • Conjugates of an EPO moiety and a polymer
    Publication number: 20060182711
    Abstract: Conjugates of an EPO moiety and one or more non-peptidic water-soluble polymers are provided. Typically, the non-peptidic water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided are compositions comprising such conjugates, methods of making conjugates, and methods of administering compositions comprising such conjugates to a patient.
    Type: Application
    Filed: February 16, 2006
    Publication date: August 17, 2006
    Inventors: Mary Bossard, Gayle Stephenson
  • Polymer factor IX moiety conjugates
    Publication number: 20060052302
    Abstract: Conjugates of a Factor IX moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided (among other things) are compositions comprising the conjugates, methods of making the conjugates, and methods of administering to a patient compositions comprising the conjugates.
    Type: Application
    Filed: June 30, 2005
    Publication date: March 9, 2006
    Inventors: Mary Bossard, Gayle Stephenson
  • Conjugates of GM-CSF moiety and a polymer
    Publication number: 20060036080
    Abstract: Conjugates of a GM-CSF moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided are compositions comprising conjugates, methods of making conjugates, and methods of administering compositions comprising conjugates to a patient.
    Type: Application
    Filed: July 14, 2005
    Publication date: February 16, 2006
    Inventors: Mary Bossard, Ping Zhang
  • Method for universal enzymatic production of bioactive peptides
    Publication number: 20060008870
    Abstract: The invention provides methods for making peptides from a polypeptide containing at least one copy of the peptide using clostripain to excise the peptide from the polypeptide. The methods enable the use of a single, highly efficient enzymatic cleavage to produce any desired peptide sequence.
    Type: Application
    Filed: November 24, 2004
    Publication date: January 12, 2006
    Inventors: Fred Wagner, Peng Luan, Yuannan Xia, Daniel Strydom, Edwin Merrifield, Mary Bossard, Barton Holmquist, Jin Seo
  • Method for enzymatic production of GLP-1 (7-36) amide peptides
    Publication number: 20050260701
    Abstract: The invention provides methods for making peptides from a polypeptide containing at least one copy of the peptide using clostripain to excise the peptide from the polypeptide. The methods enable the use of a single, highly efficient enzymatic cleavage to produce any desired peptide sequence.
    Type: Application
    Filed: November 24, 2004
    Publication date: November 24, 2005
    Inventors: Fred Wagner, Peng Luan, Yuannan Xia, Mary Bossard, Barton Holmquist, Edwin Merrifield, Daniel Strydom
  • Compositions comprising two different populations of polymer-active agent conjugates
    Publication number: 20050186174
    Abstract: Compositions comprising two different populations of polymer-active agent conjugates, wherein the weight average molecular weight of the polymers associated with each population is different, are provided. Also provided are methods preparing such compositions and methods for administering such compositions.
    Type: Application
    Filed: December 10, 2004
    Publication date: August 25, 2005
    Inventor: Mary Bossard