Patents by Inventor Mary C. Guttieri

Mary C. Guttieri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLUBLE AND MEMBRANE-ANCHORED FORMS OF LASSA VIRUS SUBUNIT PROTEINS
    Publication number: 20140377740
    Abstract: Soluble and membrane-anchored forms of Lassa virus (LASV) glycoprotein 1 (GP1), glycoprotein 2 (GP2), the glycoprotein precursor (GPC), the nucleocapsid protein (NP), and the nucleic acids encoding these proteins are disclosed, as well as diagnostic and preventative methods using these compositions. Also disclosed are methods including preparation of vaccines, factors (e.g. small molecules) that inhibit LASV infectivity, and diagnostic and therapeutic antibodies including neutralizing antibodies for the prevention and treatment of infection by LASV and other arenaviruses.
    Type: Application
    Filed: January 30, 2014
    Publication date: December 25, 2014
    Applicants: BIOFACTURA, INC., THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND
    Inventors: Luis M. BRANCO, Alexander MATSCHINER, Megan M. ILLICK, Darryl B. SAMPEY, Robert F. GARRY, Daniel G. BAUSCH, Joseph N. FAIR, Mary C. GUTTIERI, Kathleen A. CASHMAN, Russell B. WILSON, Peter C. KULAKOSKY, F. Jon GESKE
  • SOLUBLE AND MEMBRANE ANCHORED FORMS OF LASSA VIRUS SUBUNIT PROTEINS
    Publication number: 20100261640
    Abstract: The invention discloses compositions comprising soluble and membrane-anchored forms of Lassa virus (LASV) glycoprotein 1 (GP1), glycoprotein 2 (GP2), the glycoprotein precursor (GPC), the nucleocapsid protein (NP), and the nucleic acids encoding these proteins. This invention further relates to diagnostic and preventative methods using these compositions. Preventative methods include preparation of vaccines, as well as factors (e.g. small molecules) that inhibit LASV infectivity. Further, the invention relates to diagnostic and therapeutic antibodies including neutralizing antibodies for the prevention and treatment of infection by LASV and other arenaviruses.
    Type: Application
    Filed: April 10, 2008
    Publication date: October 14, 2010
    Inventors: Luis M. Branco, Alexander Matschiner, Megan M. Illick, Darryl B. Sampey, Robert F. Garry, Daniel G. Bausch, Joseph N. Fair, Mary C. Guttieri, Kathleen A. Cashman, Russell B. Wilson, Peter C. Kulakosky, F. Jon Geske
  • Antibodies expressed in insect cells
    Patent number: 7795015
    Abstract: Three vectors are described which allow the conversion of Fab fragments into or single chain Fv fragments into full-length antibody molecules. Methods for using the vectors and the resulting antibodies are also described.
    Type: Grant
    Filed: March 8, 2002
    Date of Patent: September 14, 2010
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Mary C. Guttieri, Connie S. Schmaljohn
  • Antibodies expressed in insect cells
    Publication number: 20020197677
    Abstract: Three vectors are described which allow the conversion of Fab fragments into or single chain Fv fragments into full-length antibody molecules. Methods for using the vectors and the resulting antibodies are also described.
    Type: Application
    Filed: March 8, 2002
    Publication date: December 26, 2002
    Inventors: Mary C. Guttieri, Connie S. Schmaljohn