Patents by Inventor Mary E. Gerritsen

Mary E. Gerritsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of dry eye
    Patent number: 9572811
    Abstract: The present disclosure provides a method of treating dry eye by inhibition of Bruton's tyrosine kinase (hereinafter “BTK”) inhibitors, pharmaceutical formulations comprising the same, and processes for preparing such compounds.
    Type: Grant
    Filed: July 31, 2013
    Date of Patent: February 21, 2017
    Assignee: PRINCIPIA BIOPHARMA INC.
    Inventors: Martin Babler, Mary E. Gerritsen
  • Formulations and methods for vascular permeability-related diseases or conditions
    Patent number: 9452156
    Abstract: Described herein are formulations and methods for treating, inhibiting, preventing, delaying onset, or causing regression of a disease or condition relating to vascular permeability.
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: September 27, 2016
    Assignee: SANTEN PHARMACEUTICAL CO., LTD.
    Inventors: David M. Kleinman, Thierry Nivaggioli, Mary E. Gerritsen, David A. Weber
  • FORMULATIONS AND METHODS FOR VASCULAR PERMEABILITY-RELATED DISEASES OR CONDITIONS
    Publication number: 20150265581
    Abstract: Described herein are formulations and methods for treating, inhibiting, preventing, delaying onset, or causing regression of a disease or condition relating to vascular permeability.
    Type: Application
    Filed: April 30, 2013
    Publication date: September 24, 2015
    Inventors: David M. KLEINMAN, Thierry NIVAGGIOLI, Mary E. GERRITSEN, David A. WEBER
  • TREATMENT OF DRY EYE
    Publication number: 20150182530
    Abstract: The present disclosure provides a method of treating dry eye by inhibition of Bruton's tyrosine kinase (hereinafter “BTK”) inhibitors, pharmaceutical formulations comprising the same, and processes for preparing such compounds.
    Type: Application
    Filed: July 31, 2013
    Publication date: July 2, 2015
    Applicant: PRINCIPIA BIOPHARMA INC.
    Inventors: Martin Babler, Mary E. Gerritsen
  • Formulations and methods for vascular permeability-related diseases or conditions
    Patent number: 8486960
    Abstract: Described herein are formulations and methods for treating, inhibiting, preventing, delaying onset, or causing regression of a disease or condition relating to vascular permeability.
    Type: Grant
    Filed: June 21, 2012
    Date of Patent: July 16, 2013
    Assignee: Santen Pharmaceutical Co., Ltd.
    Inventors: David M. Kleinman, Thierry Nivaggioli, Mary E. Gerritsen, David A. Weber
  • FORMULATIONS AND METHODS FOR VASCULAR PERMEABILITY-RELATED DISEASES OR CONDITIONS
    Publication number: 20120329759
    Abstract: Described herein are formulations and methods for treating, inhibiting, preventing, delaying onset, or causing regression of a disease or condition relating to vascular permeability.
    Type: Application
    Filed: June 21, 2012
    Publication date: December 27, 2012
    Applicant: Santen Pharmaceutical Co., Ltd.
    Inventors: David M. KLEINMAN, Thierry NIVAGGIOLI, Mary E. GERRITSEN, David A. WEBER
  • Formulations and methods for vascular permeability-related diseases or conditions
    Patent number: 8222271
    Abstract: Described herein are formulations and methods for treating, inhibiting, preventing, delaying onset, or causing regression of a disease or condition relating to vascular permeability.
    Type: Grant
    Filed: March 23, 2007
    Date of Patent: July 17, 2012
    Assignee: Santen Pharmaceutical Co., Ltd.
    Inventors: David M. Kleinman, Thierry Nivaggioli, Mary E. Gerritsen, David A. Weber
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20100261217
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: December 19, 2006
    Publication date: October 14, 2010
    Inventors: Kevin P. Baker, Luc Desnoyers, Mary E. Gerritsen, Audrey Goddard, Paul J. Godowski, J. Christopher Grimaldi, Austin L. Gurney, Victoria Smith, Jean-Philippe F. Stephan, Colin K. Watanabe, William I. Wood
  • PRO9907 antibodies
    Patent number: 7777007
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: August 14, 2002
    Date of Patent: August 17, 2010
    Assignee: Genentech, Inc.
    Inventors: Kevin P. Baker, Luc Desnoyers, Mary E. Gerritsen, Audrey Goddard, Paul J. Godowski, J. Christopher Grimaldi, Austin L. Gurney, Victoria Smith, Jean-Philippe F. Stephan, Colin K. Watanabe, William I. Wood
  • Antibodies to human ErbB4
    Publication number: 20100190964
    Abstract: The present invention concerns methods and means for controlling excessive proliferation and/or migration of smooth muscle cells, and in particular for treating stenosis, by using antagonists of a native ErbB4 receptor. The invention further concerns a method for the identification of ErbB4 agonists and antagonists capable of inhibiting or enhancing the proliferation or migration of smooth muscle cells.
    Type: Application
    Filed: April 2, 2010
    Publication date: July 29, 2010
    Inventors: Mary E. Gerritsen, Mark X. Sliwkowski
  • ErbB4 antagonists
    Patent number: 7704498
    Abstract: The present invention concerns methods and means for controlling excessive proliferation and/or migration of smooth muscle cells, and in particular for treating stenosis, by using antagonists of a native ErbB4 receptor. The invention further concerns a method for the identification of ErbB4 agonists and antagonists capable of inhibiting or enhancing the proliferation or migration of smooth muscle cells.
    Type: Grant
    Filed: June 24, 2008
    Date of Patent: April 27, 2010
    Assignee: Genentech, Inc.
    Inventors: Mary E. Gerritsen, Mark X. Sliwkowski
  • PRO350 antibodies
    Patent number: 7700736
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: April 15, 2002
    Date of Patent: April 20, 2010
    Assignee: Genetech, Inc.
    Inventors: Kevin P. Baker, Maureen Beresini, Laura DeForge, Luc Desnoyers, Ellen Filvaroff, Wei-Qiang Gao, Mary E. Gerritsen, Audrey Goddard, Paul J. Godowski, Austin L. Gurney, Steven Sherwood, Victoria Smith, Timothy A. Stewart, Daniel Tumas, Colin K. Watanabe, William I. Wood, Zemin Zhang
  • SECRETED AND TRANSMEMBRANE POLYPEPTIDES AND NUCLEIC ACIDS ENCODING THE SAME
    Publication number: 20090226953
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: November 13, 2008
    Publication date: September 10, 2009
    Applicant: Genentech, Inc.
    Inventors: Kevin P. Baker, Luc Desnoyers, Mary E. Gerritsen, Audrey Goddard, Paul J. Godowski, J. Christopher Grimaldi, Austin L. Gurney, Victoria Smith, Jean-Philippe F. Stephan, Colin K. Watanabe, William I. Wood
  • Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same
    Publication number: 20090209732
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: October 4, 2006
    Publication date: August 20, 2009
    Applicant: Genentech, Inc.
    Inventors: Kevin P. Baker, Maureen Beresini, Laura DeForge, Luc Desnoyers, Ellen Filvaroff, Wei-Qiang Gao, Mary E. Gerritsen, Audrey Goddard, Paul J. Godowski, Austin L. Gurney, Steven Sherwood, Victoria Smith, Timothy A. Stewart, Daniel Tumas, Colin K. Watanabe, William I. Wood, Zemin Zhang
  • Methods and compositions for selective modulation of vascularization
    Patent number: 7572447
    Abstract: The invention provides methods and compositions for modulating vascularization and angiogenesis, including selective modulation of stages of multi-step vascularization and angiogenesis.
    Type: Grant
    Filed: March 12, 2008
    Date of Patent: August 11, 2009
    Assignee: Genentech, Inc.
    Inventors: Mary E. Gerritsen, Jo-Anne S. Hongo, Constance H. Zlot
  • Anti-PRO335 antibodies
    Patent number: 7557192
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: July 12, 2001
    Date of Patent: July 7, 2009
    Assignee: Genentech, Inc.
    Inventors: Avi Ashkenazi, David Botstein, Luc Desnoyers, Dan L. Eaton, Napoleone Ferrara, Ellen Filvaroff, Sherman Fong, Wei-Giang Gao, Hanspeter Gerber, Mary E. Gerritsen, Audrey Goddard, Paul J. Godowski, J. Christopher Grimaldi, Austin L. Gurney, Kenneth J. Hillan, Ivar J. Kljavin, Jennie P. Mather, James Pan, Nicholas F. Paoni, Margaret Ann Roy, Timothy A. Stewart, Daniel Tumas, P. Mickey Williams, William I. Wood
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20090170158
    Abstract: The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: March 25, 2008
    Publication date: July 2, 2009
    Inventors: Kevin P. Baker, David Botstein, Dan L. Eaton, Napoleone Ferrara, Ellen Filvaroff, Mary E. Gerritsen, Audrey Goddard, Paul J. Godowski, J. Christopher Grimaldi, Austin L. Gurney, Kenneth J. Hillan, Ivar J. Kljavin, Mary A. Napier, Margaret Ann Roy, Daniel Tumas, William I. Wood
  • SECRETED AND TRANSMEMBRANE POLYPEPTIDES AND NUCLEIC ACIDS ENCODING THE SAME
    Publication number: 20090142786
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: February 2, 2009
    Publication date: June 4, 2009
    Applicant: GENENTECH, INC.
    Inventors: KEVIN P. BAKER, MAUREEN BERESINI, LAURA DEFORGE, LUC DESNOYERS, ELLEN FILVAROFF, WEI-QIANG GAO, MARY E. GERRITSEN, AUDREY GODDARD, PAUL J. GODOWSKI, AUSTIN L. GURNEY, STEVEN SHERWOOD, VICTORIA SMITH, TIMOTHY A. STEWART, DANIEL TUMAS, COLIN K. WATANABE, WILLIAM I. WOOD, ZEMIN ZHANG
  • PRO1550 POLYPEPTIDES AND NUCLEIC ACIDS ENCODING THE SAME
    Publication number: 20090136997
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: October 30, 2007
    Publication date: May 28, 2009
    Applicant: Genentech, Inc.
    Inventors: Dan L. Eaton, Ellen Filvaroff, Mary E. Gerritsen, Audrey Goddard, Paul J. Godowski, J. Christopher Grimaldi, Austin L. Gurney, Colin K. Watanabe, William I. Wood
  • PRO10275 polypeptides
    Patent number: 7504480
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: March 17, 2009
    Assignee: Genentech, Inc.
    Inventors: Kevin P. Baker, Audrey Goddard, Austin L. Gurney, William I. Wood, Mary E. Gerritsen, Paul J. Godowski