Patents by Inventor Mary E. Klotman

Mary E. Klotman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of inhibiting viral infection
    Patent number: 7754687
    Abstract: The present invention is directed to methods of preventing and/or treating infectious disease. In a particular aspect, the invention is directed to treating viral infections by administering an isolated Prothymosin alpha molecule (SEQ ID NO: 2) to a subject in a therapeutically effective amount that reduces the symptoms associated with the viral infection. In a more particular embodiment, the viral infection is caused by a retrovirus, a lentivirus, or a hepatitis virus. In a particular aspect, the viral infection is caused by human immunodeficiency virus-1.
    Type: Grant
    Filed: February 23, 2006
    Date of Patent: July 13, 2010
    Assignee: Mount Sinai School of Medicine
    Inventors: Arevik Mosoian, Mary E. Klotman, Avelino Teixeira
  • TREATMENT AND PREVENTION OF RENAL DISEASE
    Publication number: 20090220515
    Abstract: The present invention is directed to a method of treating or preventing renal disease in a subject. This method involves administering the subject an agent which inhibits FAT10 expression in the subject under conditions effective to prevent or treat renal disease. Also disclosed is a method of screening for agents effective in treating or preventing renal disease.
    Type: Application
    Filed: February 13, 2007
    Publication date: September 3, 2009
    Applicant: MOUNT SINAI SCHOOL OF MEDICINE
    Inventors: Michael J. Ross, Paul E. Klotman, Mary E. Klotman
  • Inhibitors of HIV infection
    Patent number: 6358511
    Abstract: The present invention is directed to novel inhibitory compounds which are capable of reducing, eliminating, or preventing human immunodeficiency virus (HIV) infection. These compounds may be polypeptides or peptides comprising particular sequences that inhibit HIV-1 infection. These compounds may be derived from CD8+ lymphocytes. The invention is also directed to novel CD8+ cell lines which secrete these novel inhibitors. The invention is further directed to compositions comprising an inhibitor of the invention and to methods for the use of such compositions in the prevention and/or treatment of HIV infection.
    Type: Grant
    Filed: May 3, 1999
    Date of Patent: March 19, 2002
    Assignee: Mount Sinai School of Medicine of the City University of New York
    Inventors: Mary E. Klotman, Mosoian Arevik, Teixeira Avelino