Patents by Inventor Mary Elizabeth FOWLER

Mary Elizabeth FOWLER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220162658
    Abstract: In various aspects and embodiments, the invention provides microbial cells and methods for producing advanced glycosylation products from lower glycosylated intermediates. The microbial cell expresses one or more UDP-dependent glycosyl transferase enzymes in the cytoplasm, for glycosylation of the intermediates. When incubating the microbial strain with a plant extract or fraction thereof comprising the intermediates, these glycosylated intermediates are available for further glycosylation by the cell, and the advanced glycosylation products can be recovered from the media and/or microbial cells.
    Type: Application
    Filed: December 9, 2021
    Publication date: May 26, 2022
    Inventors: Ajikumar Parayil KUMARAN, Christine Nicole S. SANTOS, Jason Eric DONALD, Mary Elizabeth FOWLER, Ryan N. PHILIPPE, Christopher Scott FREI, Aaron LOVE
  • Patent number: 11230724
    Abstract: In various aspects and embodiments, the invention provides microbial cells and methods for producing advanced glycosylation products from lower glycosylated intermediates. The microbial cell expresses one or more UDP-dependent glycosyl transferase enzymes in the cytoplasm, for glycosylation of the intermediates. When incubating the microbial strain with a plant extract or fraction thereof comprising the intermediates, these glycosylated intermediates are available for further glycosylation by the cell, and the advanced glycosylation products can be recovered from the media and/or microbial cells.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: January 25, 2022
    Assignee: MANUS BIO INC.
    Inventors: Ajikumar Parayil Kumaran, Christine Nicole S. Santos, Jason Eric Donald, Mary Elizabeth Fowler, Ryan N. Philippe, Christopher Scott Frei, Aaron Love
  • Publication number: 20200087692
    Abstract: In various aspects and embodiments, the invention provides microbial cells and methods for producing advanced glycosylation products from lower glycosylated intermediates. The microbial cell expresses one or more UDP-dependent glycosyl transferase enzymes in the cytoplasm, for glycosylation of the intermediates. When incubating the microbial strain with a plant extract or fraction thereof comprising the intermediates, these glycosylated intermediates are available for further glycosylation by the cell, and the advanced glycosylation products can be recovered from the media and/or microbial cells.
    Type: Application
    Filed: July 16, 2019
    Publication date: March 19, 2020
    Inventors: Ajikumar Parayil KUMARAN, Christine Nicole S. SANTOS, Jason Eric DONALD, Mary Elizabeth FOWLER, Ryan N. PHILIPPE, Christopher Scott FREI, Aaron LOVE