Patents by Inventor Mary Elizabeth Patti

Mary Elizabeth Patti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF POST-BARIATRIC HYPOGLYCEMIA USING MINI-DOSE STABLE GLUCAGON
    Publication number: 20210030847
    Abstract: Post-bariatric hypoglycemia (PBH) is an increasingly-recognized complication of gastric bypass surgery. Current therapeutic options have suboptimal efficacy. Small doses of stable liquid glucagon can be used to treat or prevent post-bariatric hypoglycemia.
    Type: Application
    Filed: January 23, 2019
    Publication date: February 4, 2021
    Applicants: XERIS PHARMACEUTICALS, INC., Joslin Diabetes Center, Inc.
    Inventors: Brett NEWSWANGER, Steven J. PRESTRELSKI, Mary-Elizabeth PATTI
  • METHODS AND COMPOSITIONS FOR TREATING HYPOGLYCEMIA
    Publication number: 20190351017
    Abstract: The invention provides methods and compositions relating to molecular targets associated with treating or preventing hypoglycemia. Included in the invention are methods and compositions relating to inhibiting the expression or activity of a glucose modulating agent associated with hypoglycemia e.g., Fibroblast Growth Factor 19 (FGF19). Also included in the invention are methods and compositions for increasing the blood glucose level of a subject. Additional aspects of the invention relate to methods for determining whether a subject has or is at risk for developing hypoglycemia, for example, post-bariatric hypoglycemia.
    Type: Application
    Filed: February 1, 2019
    Publication date: November 21, 2019
    Inventors: Mary-Elizabeth Patti, Allison Goldfine
  • Inhibiting striated muscle activator of RHO (stars) to improve glycemic control
    Patent number: 8815799
    Abstract: Described are methods of improving glycemic control/improving insulin sensitivity by administering an inhibitor of Striated Muscle Activator of Rho Signaling (STARS) activity, and methods of identifying new compounds for use in the described methods of treatment.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: August 26, 2014
    Assignee: Joslin Diabetes Center, Inc.
    Inventors: Mary Elizabeth Patti, Wanzhu Jin, Allison B. Goldfine
  • Inhibiting serum response factor (SRF) to improve glycemic control
    Patent number: 8524661
    Abstract: Described are methods of improving glycemic control/improving insulin sensitivity by administering an inhibitor of serum response factor (SRF) activity, and methods of identifying new compounds for use in the described methods of treatment.
    Type: Grant
    Filed: July 11, 2011
    Date of Patent: September 3, 2013
    Assignee: Joslin Diabetes Center, Inc.
    Inventors: Mary Elizabeth Patti, Wanzhu Jin, Allison B. Goldine
  • INHIBITING STRIATED MUSCLE ACTIVATOR OF RHO (STARS) TO IMPROVE GLYCEMIC CONTROL
    Publication number: 20130197058
    Abstract: Described are methods of improving glycemic control/improving insulin sensitivity by administering an inhibitor of Striated Muscle Activator of Rho Signaling (STARS) activity, and methods of identifying new compounds for use in the described methods of treatment.
    Type: Application
    Filed: June 3, 2011
    Publication date: August 1, 2013
    Applicant: JOSLIN DIABETES CENTER, INC.
    Inventors: Mary Elizabeth Patti, Wanzhu Jin, Allison B. Goldfine
  • Inhibiting Serum Response Factor (SRF) to Improve Glycemic Control
    Publication number: 20120028895
    Abstract: Described are methods of improving glycemic control/improving insulin sensitivity by administering an inhibitor of serum response factor (SRF) activity, and methods of identifying new compounds for use in the described methods of treatment.
    Type: Application
    Filed: July 11, 2011
    Publication date: February 2, 2012
    Applicant: Joslin Diabetes Center, Inc.
    Inventors: Mary Elizabeth Patti, Wanzhu Jin, Allison B. Goldfine
  • Inhibiting serum response factor (SRF) to improve insulin sensitivity
    Patent number: 8003606
    Abstract: Described are methods of improving glycemic control/improving insulin sensitivity by administering an inhibitor of serum response factor (SRF) activity, and methods of identifying new compounds for use in the described methods of treatment.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: August 23, 2011
    Assignee: Joslin Diabetes Center, Inc.
    Inventors: Mary Elizabeth Patti, Wanzhu Jin, Allison B. Goldfine
  • Inhibiting Serum Response Factor (SRF) to Improve Glycemic Control
    Publication number: 20100010074
    Abstract: Described are methods of improving glycemic control/improving insulin sensitivity by administering an inhibitor of serum response factor (SRF) activity, and methods of identifying new compounds for use in the described methods of treatment.
    Type: Application
    Filed: June 5, 2009
    Publication date: January 14, 2010
    Applicant: Joslin Diabetes Center, Inc.
    Inventors: Mary Elizabeth Patti, Wanzhu Jin, Allison B. Goldfine