Patents by Inventor Mary Elizabeth Yacyshyn

Mary Elizabeth Yacyshyn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of diagnosing infection or recurrence in a subject
    Patent number: 11085912
    Abstract: Methods are described for identifying CDI patients as well as CDI patients at risk for recurrence. Embodiments include: (1) flow cytometry of circulating peripheral blood mononuclear cells (PBMC) to phenotype for the less efficient immunoglobulin response to bacterial toxins and surface antigens that characterizes patients who will become recurrent; (2) stratification by means of complete blood count (CBC) using a Coulter counter to detect the differences in lower angle light scatter (LAL), which has a larger range in the recurrent population; and (3) stratification by means of complete blood count (CBC) using a Coulter counter to detect the lower axial light loss (AL2) exhibited in recurrent patients.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: August 10, 2021
    Assignee: University of Cincinnati
    Inventors: Mary Elizabeth Yacyshyn, Bruce R. Yacyshyn, Julianne Qualtieri
  • METHODS OF DIAGNOSING CLOSTRIDIUM DIFFICILE INFECTION OR RECURRENCE IN A SUBJECT
    Publication number: 20180164282
    Abstract: Methods are described for identifying CDI patients as well as CDI patients at risk for recurrence. Embodiments include: (1) flow cytometry of circulating peripheral blood mononuclear cells (PBMC) to phenotype for the less efficient immunoglobulin response to bacterial toxins and surface antigens that characterizes patients who will become recurrent; (2) stratification by means of complete blood count (CBC) using a Coulter counter to detect the differences in lower angle light scatter (LAL), which has a larger range in the recurrent population; and (3) stratification by means of complete blood count (CBC) using a Coulter counter to detect the lower axial light loss (AL2) exhibited in recurrent patients.
    Type: Application
    Filed: December 14, 2017
    Publication date: June 14, 2018
    Inventors: Mary Elizabeth Yacyshyn, Bruce R. Yacyshyn, Julianne Qualtieri