Patents by Inventor Mary Ellexson

Mary Ellexson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Class I sequence based typing of HLA-A, -B, and -C alleles by direct DNA sequencing
    Publication number: 20070128629
    Abstract: There is provided a method for directly typing or sequencing HLA-A, -B, or -C alleles from a tissue sample wherein exons 2 and 3 of the HLA-A, -B, or -C alleles from the sample are amplified together in a locus specific manner and then separated out and individually amplified in a locus specific manner. After the two amplifications, the amplified exons are directly sequenced, the sequences are recombined, and a comparison is made between the derived HLA allele sequence and an HLA allele database, thereby giving an exact HLA-A, -B, or -C type for the sample being tested.
    Type: Application
    Filed: September 20, 2006
    Publication date: June 7, 2007
    Inventors: William Hildebrand, Mary Ellexson, Pierre Chretlen, R. Duthie
  • Class I sequence based typing of HLA-A, -B, and -C alleles by direct DNA sequencing
    Publication number: 20040110192
    Abstract: There is provided a method for directly typing or sequencing HLA-A, -B, or -C alleles from a tissue sample wherein exons 2 and 3 of the HLA-A, -B, or -C alleles from the sample are amplified together in a locus specific manner and then separated out and individually amplified in a locus specific manner. After the two amplifications, the amplified exons are directly sequenced, the sequences are recombined, and a comparison is made between the derived HLA allele sequence and an HLA allele database, thereby giving an exact HLA-A, -B, or -C type for the sample being tested.
    Type: Application
    Filed: July 28, 2003
    Publication date: June 10, 2004
    Inventors: William H. Hildebrand, Mary Ellexson, Pierre Chretien, R. Scott Duthie
  • Class I sequence based typing of HLA-A, -B, and -C alleles by direct DNA sequencing
    Publication number: 20030017458
    Abstract: There is provided a method for directly typing or sequencing HLA-A, -B, or -C alleles from a tissue sample wherein exons 2 and 3 of the HLA-A, -B, or -C alleles from the sample are amplified together in a locus specific manner and then separated out and individually amplified in a locus specific manner. After the two amplifications, the amplified exons are directly sequenced, the sequences are recombined, and a comparison is made between the derived HLA allele sequence and an HLA allele database, thereby giving an exact HLA-A, -B, or -C type for the sample being tested.
    Type: Application
    Filed: May 1, 2001
    Publication date: January 23, 2003
    Inventors: William H. Hildebrand, Mary Ellexson, Pierre Chretien, R. Scott Duthie
  • Class I sequence based typing of HLA-A, -B, and -C alleles by direct DNA sequencing
    Patent number: 6287764
    Abstract: There is provided a method for directly typing or sequencing HLA-A, -B, or -C alleles from a tissue sample wherein exons 2 and 3 of the HLA-A, -B, or -C alleles from the sample are amplified together in a locus specific manner and then separated out and individually amplified in a locus specific manner. After the two amplifications, the amplified exons are directly sequenced, the sequences are recombined, and a comparison is made between the derived HLA allele sequence and an HLA allele database, thereby giving an exact HLA-A, -B, or -C type for the sample being tested.
    Type: Grant
    Filed: February 11, 1998
    Date of Patent: September 11, 2001
    Inventors: William H. Hildebrand, Mary Ellexson, Pierre Chretien, R. Scott Duthie