Patents by Inventor MARY G. GUTIERREZ

MARY G. GUTIERREZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • G PROTEIN-COUPLED RECEPTORS INCORPORATED INTO REHYDRATED POLYMER VESICLES RETAIN FUNCTIONALITY
    Publication number: 20180177729
    Abstract: A G Protein Coupled Receptor (GPCR) is incorporated in polymeric giant unilamellar protein vesicles (pGUPs). By utilizing an agarose rehydration technique, the GPCR is inserted in the biased, physiological orientation with the C-terminus cytosolic and N-terminus extracellular. The GPCR is fully functional within the polymeric bilayer, exhibiting physiological responses to various ligands. The entire population of GPCRs in pGUPs remains fully functional after lyophilization for 120 hours.
    Type: Application
    Filed: December 27, 2017
    Publication date: June 28, 2018
    Inventors: MARY G. GUTIERREZ, NOAH MALMSTADT, CARSON RICHE