Abstract: Microbicidal and spermicidal devices, methods, and compositions containing sodium dodecyl sulfate or related anionic surfactants as active ingredients for the prevention and control of pregnancy and sexually transmitted disease, including conditions caused by non-enveloped viruses such as human papilloma virus.

Abstract: Microbicidal and spermicidal devices, methods, and compositions containing sodium dodecyl sulfate or related anionic surfactants as active ingredients for the prevention and control of pregnancy and sexually transmitted disease, including conditions caused by non-enveloped viruses such as human papilloma virus.

Abstract: A method for screening candidate antimicrobial compounds is described that utilizes a human vaginal xenograft engrafted in a non-human host. The method may be performed by using pathogen inoculated human vaginal xenografts in order to screen a wide range of candidate antimicrobials administered topically or systemically.

Abstract: Microbicidal and spermicidal devices, methods, and compositions containing sodium dodecyl sulfate or related anionic surfactants as active ingredients for the prevention and control of pregnancy and sexually transmitted disease, including conditions caused by non-enveloped viruses such as human papilloma virus.

Abstract: A method for screening candidate antimicrobial compounds is described that utilizes a human vaginal xenograft engrafted in a non-human host. The method may be performed by using pathogen inoculated human vaginal xenografts in order to screen a wide range of candidate antimicrobials administered topically or systemically.

Abstract: A method for screening candidate antimicrobial compounds is described that utilizes a human vaginal xenograft engrafted in a non-human host. The method may be performed by using pathogen inoculated human vaginal xenografts in order to screen a wide range of candidate antimicrobials administered topically or systemically.

Abstract: A method for screening candidate antimicrobial compounds is described that utilizes a human vaginal xenograft engrafted in a non-human host. The method may be performed by using pathogen inoculated human vaginal xenografts in order to screen a wide range of candidate antimicrobials administered topically or systemically.

Abstract: Microbicidal and spermicidal methods and topical pharmaceutical compositions containing sodium dodecyl sulfate or its derivatives as active ingredients for the prevention and control of pregnancy and sexually transmitted diseases, including human papilloma viruses. Spermicidal barriers and microbial disinfectants containing the compositions are also provided.

Abstract: Processes for propagating a fastidious human virus in the laboratory and producing purified viral suspensions of such a virus are disclosed. The virus is extracted from tissue which contains it, and the extract is used to infect human tissue known to be susceptible to that virus. The infected tissue is placed beneath the renal capsule of an immuno-compromised animal and allowed to remain in the animal until recoverable quantities of the virus are produced. The virus is then recovered from the infected tissue and is purified. Also disclosed are variations of the process, used for detecting a fastidious human virus, for determining the infectivity of a sample containing a fastidious human virus, or for determining the antiviral activity of a substance. Finally, purified suspensions of fastidious human viruses and compositions useful as vaccines are disclosed.

Abstract: PrU.S. GOVERNMENT RIGHTSThe invention described herein was made in the course of work under a grant or award from the National Institutes of Health. The U.S. Government has certain rights in this invention pursuant to such grant or award.