Patents by Inventor Mary L. Thiesse

Mary L. Thiesse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FORMULATIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES
    Publication number: 20110044929
    Abstract: The present inventors have developed a novel composition and method for inhibiting inflammation and treating of symptoms of tissue ischemia, including that associated with peripheral and cardiac vascular disease by local administration of a pharmaceutical composition including an effective amount of a poloxamer.
    Type: Application
    Filed: August 24, 2010
    Publication date: February 24, 2011
    Applicant: Vical Incorporated
    Inventors: John Joseph REDDINGTON, Mary L. THIESSE, Isabella PIESLAK
  • GENE DELIVERY FORMULATIONS AND METHODS FOR TREATMENT OF ISCHEMIC CONDITIONS
    Publication number: 20090209630
    Abstract: The present inventors have developed a novel approach for efficient delivery of angiogenic factors to the cardiac and peripheral vasculature that avoids problems with toxicity inherent to existing delivery technologies. Vectors carrying coding sequences for angiogenic agents including Del-1 or VEGF, or both, can be formulated with poloxamers or other polymers for delivery into ischemic tissue and delivered to areas of peripheral ischemia in a flow to no-flow pattern and to the heart by retrograde venous perfusion.
    Type: Application
    Filed: May 2, 2008
    Publication date: August 20, 2009
    Applicant: Vical Incorporated
    Inventors: Michael E. Coleman, Fiona MacLaughlin, Jijun Wang, Mary L. Thiesse, Stuart Young, Jeffrey Nordstrom
  • Gene delivery formulations and methods for treatment of ischemic conditions
    Publication number: 20040009940
    Abstract: The present inventors have developed a novel approach for efficient delivery of angiogenic factors to the cardiac and peripheral vasculature that avoids problems with toxicity inherent to existing delivery technologies. Vectors carrying coding sequences for angiogenic agents including Del-1 or VEGF, or both, can be formulated with poloxamers or other polymers for delivery into ischemic tissue and delivered to areas of peripheral ischemia in a flow to no-flow pattern and to the heart by retrograde venous perfusion.
    Type: Application
    Filed: April 18, 2003
    Publication date: January 15, 2004
    Inventors: Michael E. Coleman, Fiona MacLaughlin, Jijun Wang, Mary L. Thiesse, Stuart Young, Jeffrey L. Nordstrom