Patents by Inventor Mary Lee Ciolkowski

Mary Lee Ciolkowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multifunctional Ophthalmic Compositions
    Publication number: 20090239836
    Abstract: An multifunctional ophthalmic composition includes a nonionic oxygen-containing polymer and a surfactant. The composition can be used to treat or control ophthalmic diseases, conditions, or disorders. The composition can be a drug delivery vehicle for medicaments having low solubility in water.
    Type: Application
    Filed: March 5, 2009
    Publication date: September 24, 2009
    Inventors: Mary Lee Ciolkowski, Yan Huang, Martin J. Coffey
  • Bi-directional oligonucleotides that bind thrombin
    Patent number: 5668265
    Abstract: The present invention relates to bi-directional nucleic acid ligand compounds wherein at least two oligonucleotides of opposite sequence polarity are linked to a connecting compound at their same respective terminii; either the 5' terminii or the 3 ' terminii. These compounds are useful for binding protein or small molecule targets and thus may be used as diagnostic or therapeutic agents.
    Type: Grant
    Filed: March 12, 1996
    Date of Patent: September 16, 1997
    Assignee: Becton Dickinson and Company
    Inventors: James G. Nadeau, Mary Lee Ciolkowski, Erwin A. Vogler
  • Bi-directional oligonucleotides that bind thrombin
    Patent number: 5658738
    Abstract: The present invention relates to bi-directional nucleic acid ligand compounds wherein at least two oligonucleotides of opposite sequence polarity are linked to a connecting compound at their same respective terminii; either the 5' terminii or the 3' terminii. These compounds are useful for binding protein or small molecule targets and thus may be used as diagnostic or therapeutic agents.
    Type: Grant
    Filed: December 11, 1995
    Date of Patent: August 19, 1997
    Assignee: Becton Dickinson and Company
    Inventors: James G. Nadeau, Mary Lee Ciolkowski, Erwin A. Vogler