Patents by Inventor Mary M. Hitt

Mary M. Hitt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of growing anchorage-dependent cells
    Patent number: 4335215
    Abstract: Anchorage-dependent cells are grown in agitated microcarrier suspension in which the cells and microcarriers are aggregated by periodically providing a temporary residence of said microcarriers and cells outside the main cell culture reactor agitation zone and in a separate compartment wherein they are subjected to a gentle tumbling action within a confined space having substantially the same environmental conditions as in the main cell culture reactor.
    Type: Grant
    Filed: August 27, 1980
    Date of Patent: June 15, 1982
    Assignee: Monsanto Company
    Inventors: William R. Tolbert, Mary M. Hitt, Joseph Feder, Richard C. Kimes
  • Cell culture method and apparatus
    Patent number: 4289854
    Abstract: A cell culture system and apparatus is provided for the agitated suspension culturing of mammalian cells in a flask assembly in which the culture medium and cells are gently agitated by the slow rotation of agitator means suspended downwardly in the culture medium and having at least one flexible sheet with a relatively large surface area which is positioned on the agitator in a manner to allow it to billow like a sail as liquid spills from its trailing edge during said rotation of the agitator means.
    Type: Grant
    Filed: June 20, 1980
    Date of Patent: September 15, 1981
    Assignee: Monsanto Company
    Inventors: William R. Tolbert, Mary M. Hitt, Joseph Feder
  • Production of angiogenic factor by cell culture
    Patent number: 4273871
    Abstract: Process for the production of human angiogenic factor in vitro comprising growing cells of human foreskin fibroblast cell line on support surface in nutrient culture medium at about 35.degree.-38.degree. C. for a sufficient time to elaborate angiogenic factor and recovering the resulting angiogenic factor from the cells or cell product.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: June 16, 1981
    Assignee: Monsanto Company
    Inventors: William R. Tolbert, Mary M. Hitt, Joseph Feder