Patents by Inventor Mary-Margaret O'Donnell

Mary-Margaret O'Donnell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 1-Benzyl-4-Substituted Piperazine Analogues
    Publication number: 20070249616
    Abstract: Compounds of Formula I are provided, in which variables are as described herein: Such compounds may be used to modulate MCH binding to MCH receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of metabolic, feeding and sexual disorders in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting MCH receptors (e.g., receptor localization studies).
    Type: Application
    Filed: June 15, 2007
    Publication date: October 25, 2007
    Applicant: NEUROGEN CORPORATION
    Inventors: Alan Hutchison, Bertrand Chenard, James Tarrant, Guiying Li, Manuka Ghosh, George Luke, John Peterson, Wallace Pringle, Mary-Margaret O'Donnell, Kyungae Lee, Linda Gustavson, Dario Doller
  • Substituted 1-benzyl-4-substituted piperazine analogues
    Publication number: 20060142301
    Abstract: Compounds of Formula I are provided, in which variables are as described herein: Such compounds may be used to modulate MCH binding to MCH receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of metabolic, feeding and sexual disorders in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting MCH receptors (e.g., receptor localization studies).
    Type: Application
    Filed: April 6, 2005
    Publication date: June 29, 2006
    Inventors: Alan Hutchison, Bertrand Chenard, James Tarrant, Guiying Li, Manuka Ghosh, George Luke, John Peterson, Wallace Pringle, Mary-Margaret O'Donnell, Kyungae Lee, Linda Gustavson, Dario Doller
  • Aryl-substituted piperazine derivatives
    Publication number: 20060009456
    Abstract: Aryl-substituted piperazine derivatives are provided. Such compounds may be used to modulate MCH receptor activity in vivo or in vitro, and are particularly useful in the treatment of a variety of metabolic, feeding and sexual disorders in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting MCH receptors (e.g., receptor localization studies).
    Type: Application
    Filed: June 16, 2005
    Publication date: January 12, 2006
    Inventors: Alan Hutchinson, Bertrand Chenard, Guiying Li, Manuka Ghosh, James Tarrant, Taeyoung Yoon, George Luke, Kyungae Lee, Mary-Margaret O'Donnell, Wallace Pringle, John Peterson, Kevin Hodgetts, Cheryl Steenstra, Dario Doller