Patents by Inventor Mary Marmion Dyszlewski

Mary Marmion Dyszlewski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilized radiopharmaceutical kits
    Patent number: 6428768
    Abstract: The present invention relates to the stabilization of radiopharmaceutical preparations and to the stabilization of components of radiopharmaceutical kits. In particular, the present invention relates to stabilization of lyophilized components of radiopharmaceutical kits by the addition of a cyclic oligosaccharide, such as, a modified or unmodified cyclodextrin, to the kit.
    Type: Grant
    Filed: May 15, 1995
    Date of Patent: August 6, 2002
    Assignee: MallincKrodt Medical, Inc.
    Inventors: Mark A. DeRosch, Edward A. Deutsch, Mary Marmion Dyszlewski, Dennis L. Nosco
  • Radiolabeled peptide compositions for site-specific targeting
    Patent number: 5830431
    Abstract: This invention relates to radiolabeled peptide compositions for radiopharmaceutical use and, more specifically, to radiolabeled peptides for diagnostic or therapeutic use having an unmodified carboxy terminal amino acid. The radiopharmaceutical composition may be used for targeting a selected biological site. The radiolabeled peptide is characterized by having its carboxy terminal amino acid in its carboxylic acid form and the peptide is coupled to a diagnostic or therapeutic radionuclide by a chelating agent. The radiopharmaceutical composition preferably comprises a radiolabeled peptide selected from the group consisting of somatostatin, an analog of somatostatin, a derivative of somatostatin and peptides capable of binding to the somatostatin receptor, where the peptide is coupled to a diagnostic or therapeutic radionuclide by a chelating agent has its carboxy terminal amino acid in its carboxylic acid form.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 3, 1998
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: Ananthachari Srinivasan, Mary Marmion Dyszlewski, Joseph E. Bugaj, Jack L. Erion
  • Peptide compositions and method of radiolabeling
    Patent number: 5804157
    Abstract: This invention relates to radiolabeled peptide compositions for radiopharmaceutical use and, more specifically, to radiolabeled peptides for diagnostic or therapeutic use having an unmodified carboxy terminal amino acid. The radiopharmaceutical composition may be used for targeting a selected biological site. The radiolabeled peptide is characterized by having its carboxy terminal amino acid in its carboxylic acid form and the peptide is coupled to a diagnostic or therapeutic radionuclide by a chelating agent. The radiopharmaceutical composition preferably comprises a radiolabeled peptide selected from the group consisting of somatostatin, an analog of somatostatin, a derivative of somatostatin and peptides capable of binding to the somatostatin receptor, where the peptide is coupled to a diagnostic or therapeutic radionuclide by a chelating agent has its carboxy terminal amino acid in its carboxylic acid form.
    Type: Grant
    Filed: December 12, 1997
    Date of Patent: September 8, 1998
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: Ananthachari Srinivasan, Mary Marmion Dyszlewski, Joseph E. Bugaj
  • Radiopharmaceutical formulations having non-stannous reductants
    Patent number: 5662882
    Abstract: The present invention relates to novel radiopharmaceutical imaging agents having non-stannous reductants. The present invention further relates to kits for forming radiopharmaceutical imaging agents, such kits including non-stannous reducing agents.
    Type: Grant
    Filed: March 23, 1995
    Date of Patent: September 2, 1997
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: James W. Brodack, Mark A. DeRosch, Edward A. Deutsch, Mary Marmion Dyszlewski