Patents by Inventor Mary Marovich

Mary Marovich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Truncated HIV envelope proteins (ENV), methods and compositions related thereto
    Patent number: 10081658
    Abstract: The instant application provides methods and related compositions pertaining to novel HIV envelope proteins. In some embodiments, the invention relates to methods and compositions for the preparation, production, and administration of isolated novel HIV envelope nucleic acid and protein sequences suitable, for example, as vaccines against HIV.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: September 25, 2018
    Assignees: Advanced BioScience Laboratories, Inc., The United States of America as Represented by the Secretary of the Army, The Henry M. Jackson Foundation for the Advancement of Military Medicines, Inc.
    Inventors: Vaniambadi Kalyanaraman, Stephen Whitney, Thomas C. VanCott, Victoria Polonis, Carl Alving, Gary R. Matyas, Mangala Rao, Mary Marovich, Francine McCutchan, Sodsai Tovanabutra, Eric Sanders-Buell
  • TRUNCATED HIV ENVELOPE PROTEINS (ENV), METHODS AND COMPOSITIONS RELATED THERETO
    Publication number: 20140220107
    Abstract: The instant application provides methods and related compositions pertaining to novel HIV envelope proteins. In some embodiments, the invention relates to methods and compositions for the preparation, production, and administration of isolated novel HIV envelope nucleic acid and protein sequences suitable, for example, as vaccines against HIV.
    Type: Application
    Filed: April 25, 2012
    Publication date: August 7, 2014
    Applicants: ADVANCED BIOSCIENCE LABORATORIES, INC., HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, THE GOVERNMENT OF THE USA, AS REPRESENTED BY THE SECRETARY
    Inventors: Vaniambadi Kalyanaraman, Stephen Whitney, Thomas C. Vancott, Victoria Polonis, Carl Alving, Gary R. Matyas, Mangala Rao, Mary Marovich, Francine McCutchan, Sodsai Tovanabutra, Eric Sanders-Buell
  • Method for the measurement of dengue virus binding inhibition
    Publication number: 20070134694
    Abstract: The invention concerns a method of detecting dengue infection by detecting anti-dengue neutralizing substances including anti-dengue antibody by measuring inhibition of dengue binding to dentritic cell-specific intracellular adhesion molecule (ICAM) 3-grabbing nonintegrin (DC-SIGN) or liver/lymph node-specific intracellular adhesion molecule (ICAM) 3-grabbing nonintegrin (L-SIGN). DC-SIGN or L-SIGN can be used expressed in transfected cell lines that normally are not infected by dengue virus. The invention also concerns a method of detecting anti-dengue drugs by their ability to inhibit binding of dengue virus to DC-SIGN or L-SIGN.
    Type: Application
    Filed: October 26, 2006
    Publication date: June 14, 2007
    Inventors: Timothy Burgess, Jeffrey Tjaden, Kevin Porter, Nicole Martin, Mary Marovich
  • Dengue virus detection measured by immunocytometry in a dendritic cell surrogate
    Publication number: 20070134695
    Abstract: The invention concerns a method for diagnosing dengue invention early after dengue virus infection. The method comprises binding dengue virus contained in sera from infected patients with dentritic cell-specific intracellular adhesion molecule (ICAM) 3-grabbing nonintegrin (DC-SIGN) or liver/lymph node-specific intracellular adhesion molecule (ICAM) 3-grabbing nonintegrin (L-SIGN). DC-SIGN or L-SIGN can be expressed in transfected B cells or adhered to other surfaces. Measurement of binding is by immunocytometry, microscopy or other antibody based methods.
    Type: Application
    Filed: October 26, 2006
    Publication date: June 14, 2007
    Inventors: Timothy Burgess, Jeffrey Tjaden, Kevin Porter, Mary Marovich