Patents by Inventor Mary Nesline

Mary Nesline has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230085564
    Abstract: A method for generating an immune score, the method comprising the steps of: (i) determining a qualitative and/or quantitative assessment of tumor infiltrating lymphocytes in a sample; (ii) determining a qualitative and/or quantitative assessment of T-cell receptor signaling in the sample; (iii) determining a qualitative and/or quantitative assessment of mutation burden in the sample; (iv) generating, using a predictive algorithm, an immune score based on the determined qualitative and/or quantitative assessment of tumor infiltrating lymphocytes, the determined qualitative and/or quantitative assessment of T-cell receptor signaling, and the determined qualitative and/or quantitative assessment of mutation burden.
    Type: Application
    Filed: September 14, 2022
    Publication date: March 16, 2023
    Applicant: OmniSeq, Inc.
    Inventors: Carl Morrison, Sarabjot Pabla, Jeffrey Conroy, Mary Nesline, Mark Gardner, Ji He, Sean Glenn
  • Patent number: 11515008
    Abstract: A method for generating an immune score, the method comprising the steps of: (i) determining a qualitative and/or quantitative assessment of tumor infiltrating lymphocytes in a sample; (ii) determining a qualitative and/or quantitative assessment of T-cell receptor signaling in the sample; (iii) determining a qualitative and/or quantitative assessment of mutation burden in the sample; (iv) generating, using a predictive algorithm, an immune score based on the determined qualitative and/or quantitative assessment of tumor infiltrating lymphocytes, the determined qualitative and/or quantitative assessment of T-cell receptor signaling, and the determined qualitative and/or quantitative assessment of mutation burden.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: November 29, 2022
    Assignee: OMNISEQ, INC.
    Inventors: Carl Morrison, Sarabjot Pabla, Jeffrey Conroy, Mary Nesline, Mark Gardner, Ji He, Sean Glenn
  • Publication number: 20180107786
    Abstract: A method for generating an immune score, the method comprising the steps of: (i) determining a qualitative and/or quantitative assessment of tumor infiltrating lymphocytes in a sample; (ii) determining a qualitative and/or quantitative assessment of T-cell receptor signaling in the sample; (iii) determining a qualitative and/or quantitative assessment of mutation burden in the sample; (iv) generating, using a predictive algorithm, an immune score based on the determined qualitative and/or quantitative assessment of tumor infiltrating lymphocytes, the determined qualitative and/or quantitative assessment of T-cell receptor signaling, and the determined qualitative and/or quantitative assessment of mutation burden.
    Type: Application
    Filed: October 6, 2017
    Publication date: April 19, 2018
    Applicant: OMNISEQ, INC.
    Inventors: Carl Morrison, Sarabjot Pabla, Jeffrey Conroy, Mary Nesline, Mark Gardner, Ji He, Sean Glenn
  • Publication number: 20160319347
    Abstract: The invention relates to the detection of genomic variants using next generation sequencing platforms, and increasing the positive predictive value and/or sensitivity of detection. The invention relates to methods and systems for detecting the presence or absence of at least one specific genetic variant, including an allelic variant, in a biological sample. Accurately detecting genetic variants can lead to more accurate diagnosis, prognosis, treatment, and/or prevention of various conditions and disease, including cancer.
    Type: Application
    Filed: November 10, 2014
    Publication date: November 3, 2016
    Applicant: Health Research Inc.
    Inventors: Carl MOrrison, Mary Nesline, Jeffrey Conroy, Christopher Darlak