Patents by Inventor Mary Pat Beavers

Mary Pat Beavers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of Human Cathepsin L, Cathepsin B, and Cathepsin S
    Publication number: 20110207726
    Abstract: The present invention is directed to novel protease inhibitors that are specific for cathepsin L, cathepsin B, and cathepsin S. Accordingly, the present invention encompasses compositions and methods for treating and preventing diseases and disorders associated with cathepsin L, cathepsin B, or cathepsin S function or activity.
    Type: Application
    Filed: April 17, 2009
    Publication date: August 25, 2011
    Inventors: Scott L. Diamond, Mary Pat Beavers, Donna Huryn, Michael C. Myers, Amos B. Smith, Parag P. Shah, Zhuqing Liu
  • Dihydroisoindolones as allosteric modulators of glucokinase
    Patent number: 7928246
    Abstract: The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Grant
    Filed: April 15, 2009
    Date of Patent: April 19, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Hiayan Bian, Joseph Dudash, Mona Patel, Philip Rybczynski, Yongzheng Zhang, Mary Pat Beavers, Maud Urbanski, Min (Amy) Xiang, Roxanne Zeck
  • Substituted indole-O-glucosides
    Patent number: 7820630
    Abstract: Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: October 26, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Mary Pat Beavers, Mona Patel, Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Substituted pyrazoles
    Patent number: 7772236
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Grant
    Filed: July 24, 2008
    Date of Patent: August 10, 2010
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • SUBSTITUTED INDOLE-O-GLUCOSIDES
    Publication number: 20100009900
    Abstract: Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Application
    Filed: September 22, 2009
    Publication date: January 14, 2010
    Inventors: Mary Pat Beavers, Mona Patel, Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Substituted pyrazoles
    Patent number: 7589202
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: September 15, 2009
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • DIHYDROISOINDOLONES AS ALLOSTERIC MODULATORS OF GLUCOKINASE
    Publication number: 20090202525
    Abstract: The present invention relates to compounds of Formula (1), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.
    Type: Application
    Filed: April 15, 2009
    Publication date: August 13, 2009
    Inventors: Haiyan Bian, Joseph Dudash, Mona Patel, Philip Rybczynski, Yongzheng Zhang, Mary Pat Beavers, Maud Urbanski, Min (Amy) Xiang, Roxanne Zeck
  • SUBSTITUTED INDOLE-O-GLUCOSIDES
    Publication number: 20090105164
    Abstract: Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Application
    Filed: December 18, 2008
    Publication date: April 23, 2009
    Inventors: Mary Pat Beavers, Mona Patel, Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Substituted indole-O-glucosides
    Patent number: 7511022
    Abstract: Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Grant
    Filed: June 15, 2006
    Date of Patent: March 31, 2009
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Mary Pat Beavers, Mona Patel, Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Substituted pyrazoles
    Publication number: 20080300255
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Application
    Filed: July 24, 2008
    Publication date: December 4, 2008
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Substituted pyrazoles
    Publication number: 20080293732
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Application
    Filed: July 24, 2008
    Publication date: November 27, 2008
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Substituted pyrazoles
    Patent number: 7452890
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: November 18, 2008
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Substituted pyrazoles
    Patent number: 7429591
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: September 30, 2008
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Substituted pyrazoles
    Patent number: 7417046
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: August 26, 2008
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Substituted pyrazoles
    Patent number: 7393850
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: July 1, 2008
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Substituted pyrazoles
    Patent number: 7388011
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: June 17, 2008
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Substituted pyrazoles
    Patent number: 7309703
    Abstract: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S are described.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: December 18, 2007
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Mary Pat Beavers, J. Guy Breitenbucher, Hui Cai, James P. Edwards, Cheryl A. Grice, Darin J. Gustin, Haripada Khatuya, Steven P. Meduna, Barbara A. Pio, Kevin L. Tays, Jianmei Wei
  • Substituted indole-O-glucosides
    Patent number: 7129220
    Abstract: Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed.
    Type: Grant
    Filed: July 30, 2004
    Date of Patent: October 31, 2006
    Assignee: Janssen Pharmaceutica N.V
    Inventors: Mary Pat Beavers, Mona Patel, Philip Rybczynski, Maud Urbanski, Xiaoyan Zhang
  • Cyclopentene derivatives useful as antagonists of the motilin receptor
    Patent number: 5972939
    Abstract: The compounds of formula I are useful in treating gastrointestinal disorders associated with antagonizing the motilin receptor disorders. The compounds compete with erythromycin and motilin for the motilin receptor. In addition the compounds are antagonists of the contractile smooth muscle response to those ligands.
    Type: Grant
    Filed: October 26, 1998
    Date of Patent: October 26, 1999
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Robert H. Chen, Min Xiang, John B. Moore, Jr., Mary Pat Beavers
  • Nipecotic acid derivatives as antithrombotic compounds
    Patent number: 5770575
    Abstract: Nipecotic acid-derived compounds of formula (I): ##STR1## are disclosed as useful in treating platelet-mediated thrombotic disorders.
    Type: Grant
    Filed: March 6, 1995
    Date of Patent: June 23, 1998
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Mary Pat Beavers, Patricia Andrade-Gordon, William J. Hoekstra