Patents by Inventor Mary Prieve

Mary Prieve has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR CULTURING HEMATOPOIETIC STEM AND PROGENITOR CELLS
    Publication number: 20230017590
    Abstract: The present disclosure provides compositions and methods for culturing hematopoietic stem and progenitor cells, while maintaining or increasing the subpopulation of hematopoietic stem cells (HSCs). The methods and compositions describe us a 3D zwitterionic hydrogel to provide a biocompatible culture microenvironment for culturing encapsulated hematopoietic stem and progenitor cells.
    Type: Application
    Filed: November 27, 2020
    Publication date: January 19, 2023
    Applicant: Deverra Therapeutics Inc.
    Inventors: Tao Bai, Devikha Chandrasekaran, Mary Prieve, Colleen Delaney
  • ORNITHINE TRANSCARBAMYLASE (OTC) CONSTRUCTS AND METHODS OF USING THE SAME
    Publication number: 20230001021
    Abstract: The present disclosure provides, among other things, polynucleotide constructs, compositions, and methods of treating ornithine transcarbamylase deficiency, including administering to a subject in need thereof a composition comprising a polynucleotide construct comprising a 5? UTR, a codon optimized mRNA encoding an ornithine transcarbamylase, and a 3? UTR.
    Type: Application
    Filed: October 22, 2020
    Publication date: January 5, 2023
    Inventors: Owen DALY, Kieu LAM, James HEYES, Richard HOLLAND, Christine ESAU, Ed YAWORSKI, Mary PRIEVE
  • NK CELL COMPOSITIONS AND PREPARATIONS FOR IMMUNOTHERAPY AND METHODS FOR THEIR PRODUCTION
    Publication number: 20220275334
    Abstract: The present invention provides NK cell compositions and/or preparations and methods of using such NK cell compositions and/or preparations for immunotherapy. The NK cell compositions and/or preparations can be used in therapies of a broad range of viral infections, bacterial infections, cancer and leukemia malignancies, and other diseases.
    Type: Application
    Filed: July 29, 2020
    Publication date: September 1, 2022
    Applicant: Deverra Therpaeutics Inc.
    Inventors: Colleen Delaney, Carrie Stoltzman, Elizabeth Dam, Mary Prieve
  • LIPIDS FOR DELIVERY OF THERAPEUTICS
    Publication number: 20180353607
    Abstract: This disclosure provides a range of amino acid lipid compounds and compositions useful for drug delivery, therapeutics, and the diagnosis and treatment of diseases and conditions. The amino acid lipid compounds and compositions can be used for delivery of various agents such as nucleic acid therapeutics to cells, tissues, organs, and subjects.
    Type: Application
    Filed: August 14, 2017
    Publication date: December 13, 2018
    Inventors: Steven C. Quay, Michael E. Houston, Jr., Pierrot Harvie, Roger C. Adami, Renata Fam, Mary Prieve, Kathy Fosnaugh, Shaguna Seth
  • Tyrosine-based lipids for delivery of therapeutics
    Patent number: 9731016
    Abstract: This disclosure provides a range of tyrosine amino acid lipid compounds and compositions useful for drug delivery, therapeutics, and the diagnosis and treatment of diseases and conditions. The amino acid lipid compounds and compositions can be used for delivery of various agents such as nucleic acid therapeutics to cells, tissues, organs, and subjects.
    Type: Grant
    Filed: April 3, 2016
    Date of Patent: August 15, 2017
    Assignee: Marina Biotech, Inc.
    Inventors: Steven C. Quay, Michael E. Houston, Jr., Pierrot Harvie, Roger C. Adami, Renata Fam, Mary Prieve, Kathy Fosnaugh, Shaguna Seth
  • TYROSINE-BASED LIPIDS FOR DELIVERY OF THERAPEUTICS
    Publication number: 20160206739
    Abstract: This disclosure provides a range of tyrosine amino acid lipid compounds and compositions useful for drug delivery, therapeutics, and the diagnosis and treatment of diseases and conditions. The amino acid lipid compounds and compositions can be used for delivery of various agents such as nucleic acid therapeutics to cells, tissues, organs, and subjects.
    Type: Application
    Filed: April 3, 2016
    Publication date: July 21, 2016
    Inventors: Steven C. Quay, Michael E. Houston, JR., Pierrot Harvie, Roger C. Adami, Renata Fam, Mary Prieve, Kathy Fosnaugh, Shaguna Seth
  • Heterogeneous polymeric micelles for intracellular delivery
    Patent number: 9211250
    Abstract: Compositions comprising a heterogeneous polymeric micelle and an agent (e.g., a polynucleotide) associated with the micelle are disclosed, together with methods for intracellular delivery of such agent.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: December 15, 2015
    Assignees: University of Washington, PhaseRx, Inc.
    Inventors: Paul Johnson, Patrick S. Stayton, Allan S. Hoffman, Robert Overell, Anna Gall, Mary Prieve, Amber Paschal, Charbel Diab, Priyadarsi De
  • HETEROGENEOUS POLYMERIC MICELLES FOR INTRACELLULAR DELIVERY
    Publication number: 20120021514
    Abstract: Compositions comprising a heterogeneous polymeric micelle and an agent (e.g., a polynucleotide) associated with the micelle are disclosed, together with methods for intracellular delivery of such agent.
    Type: Application
    Filed: May 13, 2009
    Publication date: January 26, 2012
    Applicants: PHASERX, INC., UNIVERSITY OF WASHINGTON
    Inventors: Paul Johnson, Patrick S. Stayton, Allan S. Hoffman, Robert Overell, Anna Gall, Mary Prieve, Amber Paschal, Charbel Diab, Priyadarsi De
  • MICELLES OF HYDROPHILICALLY SHIELDED MEMBRANE-DESTABILIZING COPOLYMERS
    Publication number: 20110281934
    Abstract: Provided herein are micelles comprising a plurality of copolymers. In certain instances, micelles provided herein are pH sensitive particles.
    Type: Application
    Filed: May 13, 2009
    Publication date: November 17, 2011
    Applicants: PHASERX, INC., UNIVERSITY OF WASHINGTON
    Inventors: Paul Johnson, Patrick S. Stayton, Allan S. Hoffman, Robert Overell, Anna Gall, Mary Prieve, Amber Paschal, Charbel Diab, Priyadarsi De