Patents by Inventor Mary Simcox

Mary Simcox has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF
    Publication number: 20220096640
    Abstract: Conjugates of an active agent attached to a targeting moiety, such as an HSP90 binding moiety, via a linker, and particles comprising such conjugates have been designed. Such conjugates and particles can provide improved temporospatial delivery of the active agent, improved biodistribution and penetration in tumor, and/or decreased toxicity. Methods of making the conjugates, the particles, and the formulations thereof are provided. Methods of administering the formulations to a subject in need thereof are provided, for example, to treat or prevent cancer.
    Type: Application
    Filed: December 9, 2021
    Publication date: March 31, 2022
    Inventors: Benoît Moreau, Brian H. White, Mark T. Bilodeau, Mary Simcox, Kerry Whalen, Leila Alland, Richard Wooster, Rajesh R. Shinde
  • HSP90-targeting conjugates and formulations thereof
    Patent number: 11241500
    Abstract: Conjugates of an active agent attached to a targeting moiety, such as an HSP90 binding moiety, via a linker, and particles comprising such conjugates have been designed. Such conjugates and particles can provide improved temporospatial delivery of the active agent, improved biodistribution and penetration in tumor, and/or decreased toxicity. Methods of making the conjugates, the particles, and the formulations thereof are provided. Methods of administering the formulations to a subject in need thereof are provided, for example, to treat or prevent cancer.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: February 8, 2022
    Assignee: TARVEDA THERAPEUTICS, INC.
    Inventors: Benoît Moreau, Brian H. White, Mark T. Bilodeau, Mary Simcox, Kerry Whalen, Leila Alland, Richard Wooster, Rajesh R. Shinde
  • COMBINATION THERAPIES COMPRISING TARGETED THERAPEUTICS
    Publication number: 20200230247
    Abstract: The invention generally relates to a combination therapy for treating cancer comprising administering at least two distinct therapeutic agents. Components of the combination therapy and methods of using the combination therapy are provided.
    Type: Application
    Filed: June 19, 2018
    Publication date: July 23, 2020
    Inventors: Richard Wooster, Kerry Whalen, Mary Simcox, Leila Alland, Mark T. Bilodeau, Sudhakar Kadiyala, Samantha Perino
  • HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF
    Publication number: 20200085960
    Abstract: Conjugates of an active agent attached to a targeting moiety, such as an HSP90 binding moiety, via a linker, and particles comprising such conjugates have been designed. Such conjugates and particles can provide improved temporospatial delivery of the active agent, improved biodistribution and penetration in tumor, and/or decreased toxicity. Methods of making the conjugates, the particles, and the formulations thereof are provided. Methods of administering the formulations to a subject in need thereof are provided, for example, to treat or prevent cancer.
    Type: Application
    Filed: December 14, 2017
    Publication date: March 19, 2020
    Inventors: Benoît Moreau, Brian H. White, Mark T. Bilodeau, Mary Simcox, Kerry Whalen, Leila Alland, Richard Wooster, Rajesh R. Shinde
  • NEUROTENSIN RECEPTOR BINDING CONJUGATES AND FORMULATIONS THEREOF
    Publication number: 20200078468
    Abstract: Conjugates of an active agent attached to a neurotensin receptor-binding targeting moiety via a linker have been designed. Nanoparticles and microparticles comprising such conjugates can provide improved temporospatial delivery of the active agent and/or improved biodistribution. Methods of making the conjugates, the particles, and the formulations thereof are provided. Methods of administering the formulations to a subject in need thereof are provided, for example, to treat or prevent cancer or other diseases.
    Type: Application
    Filed: April 13, 2017
    Publication date: March 12, 2020
    Inventors: Mark T. Bilodeau, Mary Simcox, Brian H. White, Sudhakar Kadiyala, Richard Wooster