Abstract: The present disclosure relates to methods for treating pancreatic ductal adenocarcinoma comprising administering to a patient in need thereof mirdametinib or a pharmaceutically acceptable salt thereof.

Abstract: An iterative methodology and system (which can also be represented in software), with the option for continual improvement, for the interactive capture, merger, comparison, analysis, cloning and manipulation of anything in the unique universe medium or multiple universes mediums, be it real, virtual or imagined, including thought (of organic or non-organic or other nature), in real time or non-real time, where anything also includes anything infinitely small (or a small base volume of space known as a Senserom), to infinitely large (or a large encapsulating Senseroom volume known as a Senseverse) and can include multiple universes and Senserooms themselves impacting each other, static or dynamic changing over time periods, including the past, present and future. The full set of these infinite Senseroms and Senserooms is considered the Senseverse, which contains anything and/or everything real, virtual and imagined.

Abstract: An iterative methodology and system (which can also be represented in software), with the option for continual improvement, for the interactive capture, merger, comparison, analysis, cloning and manipulation of anything in the unique universe medium or multiple universes mediums, be it real, virtual or imagined, including thought (of organic or non-organic or other nature), in real time or non-real time, where anything also includes anything infinitely small (or a small base volume of space known as a Senserom), to infinitely large (or a large encapsulating Senseroom volume known as a Senseverse) and can include multiple universes and Senserooms themselves impacting each other, static or dynamic changing over time periods, including the past, present and future. The full set of these infinite Senseroms and Senserooms is considered the Senseverse, which contains anything and/or everything real, virtual and imagined.

Abstract: One or more embodiments may include a method for remotely obtaining information about an energy source of a vehicle. Information identifying one or more vehicles and one or more drivers of the vehicles may be received at one or more computing devices remote from a vehicle. Instructions from the one or more remote computing devices may be transmitted requesting information from the identified vehicle(s) about a status of an energy source for the identified vehicle(s). The status information may be received at the remote computing device(s). Based on the energy source status information and the driver identifying information, a vehicle energy source status with respect to one or more attributes of the vehicle drivers may be calculated. Additionally, the vehicle energy source status may be displayed at the one or more devices.

Abstract: An iterative methodology and system (which can also be represented in software), with the option for continual improvement, for the interactive capture, merger, comparison, analysis, cloning and manipulation of anything in the unique universe medium or multiple universes mediums, be it real, virtual or imagined, including thought (of organic or non-organic or other nature), in real time or non-real time, where anything also includes anything infinitely small (or a small base volume of space known as a Senserom), to infinitely large (or a large encapsulating Senseroom volume known as a Senseverse) and can include multiple universes and Senserooms themselves impacting each other, static or dynamic changing over time periods, including the past, present and future. The full set of these infinite Senseroms and Senserooms is considered the Senseverse, which contains anything and/or everything real, virtual and imagined.

Abstract: One or more embodiments may include a method for remotely obtaining information about an energy source of a vehicle. Information identifying one or more vehicles and one or more drivers of the vehicles may be received at one or more computing devices remote from a vehicle. Instructions from the one or more remote computing devices may be transmitted requesting information from the identified vehicle(s) about a status of an energy source for the identified vehicle(s). The status information may be received at the remote computing device(s). Based on the energy source status information and the driver identifying information, a vehicle energy source status with respect to one or more attributes of the vehicle drivers may be calculated. Additionally, the vehicle energy source status may be displayed at the one or more devices.

Abstract: One or more embodiments may include a method for remotely obtaining information about an energy source of a vehicle. Information identifying one or more vehicles and one or more drivers of the vehicles may be received at one or more computing devices remote from a vehicle. Instructions from the one or more remote computing devices may be transmitted requesting information from the identified vehicle(s) about a status of an energy source for the identified vehicle(s). The status information may be received at the remote computing device(s). Based on the energy source status information and the driver identifying information, a vehicle energy source status with respect to one or more attributes of the vehicle drivers may be calculated. Additionally, the vehicle energy source status may be displayed at the one or more devices.

Abstract: A mattress or surface protector is provided. The mattress or surface protector comprises a generally non-absorbent top layer and a waterproof/breathable bottom layer. The top layer and bottom layer are connected by borders providing a mechanism to inhibit spills from traversing the edges of the protector. The borders have straps that can be secured about the corners of the mattress or surface to anchor the protector.

Abstract: An expandable notebook for retaining and displaying papers or other materials includes a binder having a pair of decorative front and back covers connected to each other by an expandable spine. The spine is made of a plicated material for expansion and contraction, and has opposing slots on each side for receiving flexible, self-locking retainer straps which are adjustable for retaining various thicknesses of material. In a preferred embodiment each retainer strap is mounted through a pair of opposing slots formed on each side of the plicated spine, thereby surrounding the spine, and when locked in place the strap forms an adjustable loop which lies between the inner surfaces of the covers, to accommodate varied thicknesses of bound material within the loop and protected within the binder covers.

Abstract: This invention relates to a semidry or dry cherry product that retains the flavor and nutraceutical ingredients of the original cherries and also has extended shelf life.

Abstract: A pocket insert for a book includes at least one pocket to receive and retain supplemental media such as a diskette. The pocket insert is bound with pages of the book along an edge that faces openings of the pocket.