Patents by Inventor Maryam HABIBIAN

Maryam HABIBIAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HYBRIDIZED GUIDE NUCLEIC ACIDS FOR USE WITH TEMPLATE-BASED GENE EDITORS
    Publication number: 20240011023
    Abstract: Polynucleotides are engineered to hybridize to one another to form a functional guide nucleic acid having an editing template. The hybridized guide nucleic acids may be used with template-based gene editors to write an edit into a target genomic location using the editing template as a template for the edit.
    Type: Application
    Filed: July 7, 2023
    Publication date: January 11, 2024
    Inventors: Vidya Subramanian, Kallanthottathil G. Rajeev, Hariharan Jayaram, Caroline Reiss, Maryam Habibian, Gitali Devi, Allison Baker
  • ELECTROCHEMICAL POLYNUCLEOTIDE SYNTHESIS
    Publication number: 20220323924
    Abstract: Provided herein are compositions, devices, systems and methods for generation and use of biomolecule-based information for storage. Further provided are devices comprising addressable electrodes controlling polynucleotide synthesis (deprotection, extension, or cleavage, etc.) Further provided are compositions for low voltage deprotection of polynucleotides.
    Type: Application
    Filed: March 23, 2022
    Publication date: October 13, 2022
    Inventors: Jeremy LACKEY, Maryam HABIBIAN, YanYou LIN
  • Tuning CRISPR/Cas9 activity with chemically modified nucleotide substitutions
    Patent number: 11306305
    Abstract: The present disclosure provides CRISPR/Cas9 ribonucleoprotein compositions comprising chemically modified CRISPR RNA (crRNA) guide and trans-acting CRISPR RNA (tracrRNA) components. Methods of using the disclosed CRISPR/Cas9 ribonucleoprotein compositions are also provided.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: April 19, 2022
    Assignees: Board of Trustees of Southern Illinois University
    Inventors: Keith Gagnon, Masad Damha, Elise Malek-Adamian, Maryam Habibian, Daniel Timothy O'Reilly, Zachery Kartje
  • DEVICES AND METHODS FOR SYNTHESIS
    Publication number: 20220064206
    Abstract: Provided herein are compositions, devices, systems and methods for electrochemical synthesis. Further provided are devices comprising addressable electrodes controlling polynucleotide synthesis (deprotection, extension, or cleavage, etc.) The compositions, devices, systems and methods described herein provide improved synthesis, storage, density, and retrieval of biomolecule-based information.
    Type: Application
    Filed: August 26, 2021
    Publication date: March 3, 2022
    Inventors: Andres FERNANDEZ, Eugene P. Marsh, Maryam HABIBIAN
  • Tuning CRISPR/CAS9 Activity with Chemically Modified Nucleotide Substitutions
    Publication number: 20190185844
    Abstract: The present disclosure provides CRISPR/Cas9 ribonucleoprotein compositions comprising chemically modified CRISPR RNA (crRNA) guide and trans-acting CRISPR RNA (tracrRNA) components. Methods of using the disclosed CRISPR/Cas9 ribonucleoprotein compositions are also provided.
    Type: Application
    Filed: September 22, 2017
    Publication date: June 20, 2019
    Applicants: Board of Trustees of Southern lllinois University, The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Keith GAGNON, Masad DAMHA, Elise MALEK-ADAMIAN, Maryam HABIBIAN, Daniel O'REILLY, Zachery KARTJE